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Cluster trials

Rare event detection by progressive clustering undersampling

Amr Abuzeid, Elena Jolkver

published 30 Jan 2026

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Power and sample size for reversible linear mixed models with clustering and longitudinality: GLIMMPSE Version 3

Deborah H. Glueck, Qian Li, Alasdair J. Macleod, Elizabeth M. Litkowski, Xi Yang, Jiang Bian, Albert D. Ritzhaupt, Max Sommer, Natercia Valle, Jessica R. Shaw, Keith E. Muller

published 03 Sep 2025

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An ADaptivE PrenaTal (ADEPT) intervention to increase childhood vaccinations: Protocol for a cluster randomized trial and nested mixed methods evaluation

Lavanya Vasudevan, Rachael M. Porter, Ilse Campos, Elizabeth L. Turner, Sandra S. Stinnett, Leah L. Zullig, Emmanuel B. Walter, Geeta K. Swamy, Robert A Bednarczyk, Walter A. Orenstein, Beverly Gray

published 21 Nov 2024

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Researchers’ experiences of the design and conduct challenges associated with parallel-group cluster-randomised trials and views on a novel open-cohort design

Claire Surr, Laura Marsden, Alys Griffiths, Sharon Cox, Jane Fossey, Adam Martin, A. Toby Prevost, Catherine Walshe, Rebecca Walwyn

published 23 Feb 2024

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Effectiveness of online training in improving primary care doctors’ competency in brief tobacco interventions: A cluster-randomized controlled trial of WHO modules in Delta State, Nigeria

Nnamdi Stephen Moeteke, Patrick Oyibo, Oboratare Ochei, Maureen Iru Ntaji, Nyemike Simeon Awunor, Mitchell Oritsewino Adeyemi, Ibobo Mike Enemuwe, Eseoghene Agbatutu, Oluwaseun Opeyemi Adesoye

published 22 Feb 2024

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Evaluating the impact of e-registration and mHealth on institutional delivery in hazard-prone areas of Bangladesh: A protocol for a non-randomized controlled cluster trial

Anika Tasneem Chowdhury, Sabrina Jabeen, Zeeba Zahra Sultana, Ahmed Ehsanur Rahman, Shams El Arifeen, Ahmed Hossain

published 27 Sep 2023

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STIMULATE-ICP: A pragmatic, multi-centre, cluster randomised trial of an integrated care pathway with a nested, Phase III, open label, adaptive platform randomised drug trial in individuals with Long COVID: A structured protocol

Denise Forshaw, Emma C. Wall, Gordon Prescott, Hakim-Moulay Dehbi, Angela Green, Emily Attree, Lyth Hismeh, William D. Strain, Michael G. Crooks, Caroline Watkins, Chris Robson, Rajarshi Banerjee, Paula Lorgelly, Melissa Heightman, Amitava Banerjee, the STIMULATE-ICP trial team

published 15 Feb 2023

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Communication interventions for medically unexplained symptom conditions in general practice: A systematic review and meta-analysis of randomised controlled trials

Ailish Katherine Byrne, Arabella Scantlebury, Katherine Jones, Laura Doherty, David J. Torgerson

published 14 Nov 2022

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Effectiveness of web-based intervention for life-change adaptation in family caregivers of community-dwelling individuals with acquired brain injury: A cluster-randomized controlled trial

Yuka Iwata (Shindo), Etsuko Tadaka

published 18 Aug 2022

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Assessment of a viral load result-triggered automated differentiated service delivery model for people taking ART in Lesotho (the VITAL study): Study protocol of a cluster-randomized trial

Nadine Tschumi, Malebanye Lerotholi, Mathebe Kopo, Mpho Kao, Blaise Lukau, Bienvenu Nsakala, Ntoiseng Chejane, Lipontso Motaboli, Tristan Lee, Ruanne Barnabas, Adrienne E. Shapiro, Alastair van Heerden, Thabo I. Lejone, Alain Amstutz, Jennifer A. Brown, Jesse Heitner, Jennifer M. Belus, Frédérique Chammartin, Niklaus D. Labhardt

published 05 May 2022

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Two-way text message interventions and healthcare outcomes in Africa: Systematic review of randomized trials with meta-analyses on appointment attendance and medicine adherence

Emilie S. Ødegård, Lena S. Langbråten, Andreas Lundh, Ditte S. Linde

published 14 Apr 2022

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Methods for dealing with unequal cluster sizes in cluster randomized trials: A scoping review

Denghuang Zhan, Liang Xu, Yongdong Ouyang, Richard Sawatzky, Hubert Wong

published 29 Jul 2021

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A power approximation for the Kenward and Roger Wald test in the linear mixed model

Sarah M. Kreidler, Brandy M. Ringham, Keith E. Muller, Deborah H. Glueck

published 21 Jul 2021

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