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Clinical research design

Hepatic arterial infusion chemotherapy (HAlC) versus sorafenib for hepatocellular carcinoma (HCC) in Barcelona Clinic Liver Cancer (BCLC) B/C: A systematic review and meta-analysis

Zhengqiang Chen, Yaotian Fan, Yuting Luo, Xiwen Ye, Zhen You

published 18 Feb 2026

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MetaMind: A multi-agent transformer-driven framework for automated network meta-analyses

Achilleas Livieratos, Maria Kudela, Yuxi Zhao, All-shine Chen, Xin Luo, Junjing Lin, Di Zhang, Sai Dharmarajan, Sotirios Tsiodras, Vivek Rudrapatna, Margaret Gamalo

published 13 Feb 2026

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Analysis and mining of adverse events associated with vorapaxar: A FAERS database-based study

Hui Zhang, Minghao Lin, Chaoqun Song, Zheng Nan, Dexi Zhao, Yujuan Fu

published 13 Feb 2026

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Disproportionality analysis of fondaparinux associated adverse events based on the FDA adverse event reporting system

Fengjiao Kang, Yin Wang, Fengqun Cai, Liuyun Wu, Lizhu Han, Qinan Yin, Yuan Bian

published 11 Feb 2026

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Study protocol for a multicenter phase II prospective externally controlled non-inferiority trial of hypofractionated re-irradiation in patients with recurrent high-grade glioma (RISinG)

A. M. de Jong, A. T. J. van der Boog, C. C. B. Post, F. Cialdella, D. B. P. Eekers, J. Hendrikse, M. C. A. Kramer, F. J. Lagerwaard, M. van der Meulen, M. E. P. Philippens, P. A. Robe, T. Rozema, F. Y. F. L. de Vos, J. Vos-Westerman, H. L. van der Weide, G. Wester, J. Zindler, T. J. Snijders, J. J. C. Verhoeff

published 09 Feb 2026

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Protocol: Effects of midazolam on postoperative delirium in elderly patients undergoing spinal surgery: A randomized, double-blind, placebo-controlled non-inferiority trial

Chaoxu Sheng, Miao Zhu, Liyong Yuan, Jianlin Wang, Bo Hu, Xiaolu Huang, He Han

published 06 Feb 2026

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Feasibility and acceptability outcomes of the InMe trial - a randomised controlled trial in participants with subclinical eating and somatic symptom disorders

Marina Bobou, Michal Tanzer, Alkistis Saramandi, Caroline Selai, Aikaterini Fotopoulou

published 04 Feb 2026

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Utility of inhaled β2-agonists in reducing serum potassium levels in adult patients with hyperkalemia: A scoping review

Leonardo Arzayus-Patiño, Ashley Y. Hinojosa-Angulo, Karen A. Rodríguez-Angulo, Michelle A. Sánchez-Caicedo, Vicente Benavides-Córdoba

published 03 Feb 2026

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Expression patterns of bone morphogenetic protein 7 (BMP7) and its prognostic roles in neuroblastoma: An integrated bioinformatics analysis

Haiwei Wang, Xinrui Wang, Liangpu Xu

published 03 Feb 2026

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Systematic analysis of proton pump inhibitors-related adverse reactions using the FDA adverse event reporting system database

Zhenyu Wang, Jianan Jin, Guimei Wang, Guoqi Zhou, Hanliang Jiang

published 02 Feb 2026

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Skin-related adverse events and their associated factors among Diabetic patients on insulin therapy

Dennis Patson Mbwambo, Wigilya Mikomangwa, Rajabu Hussein Mkugwe, Bertha Mallya, Manase Kilonzi, Method Kazaura, Magreth Angelus, Kaushik Ramaiya, Mary Mayige, Ritah Mutagonda, Alphonce Ignace Marealle

published 02 Feb 2026

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Exploring adverse events associated with vosoritide monotherapy: Insights from the FDA Adverse Event Reporting System

Xiaomin Li, Xiangli Luo, Fei Liu, Chaolu Wang, Xiaoming Li, Huaixi Yu

published 29 Jan 2026

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A randomised pilot trial of perioperative propranolol combined with celecoxib versus standard of care in stage III melanoma: The ProCel study protocol

Katina J. Selvaraj, Diona L. Damian, J. Guy Lyons, James S. Wilmott, Peter M. Ferguson, Michele McGrady, Iris Bartula, Serigne N. Lo, Richard A. Scolyer, Angela L. Ferguson, Robyn P.M. Saw

published 29 Jan 2026

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