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Chromatin

Integrative methylome and transcriptome analyses identify LHX3 as an epigenetically downregulated marker with tumor suppressive properties in breast cancer

Kokab Farooq, Sheereen Gull, Zubia Farooq, Muhammad Talal Amin, Rana Salman Anjum, Muhammad Hassan Sarfraz, Ajaz Ahmad, Naveed Shahzad

published 07 Oct 2026

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Optimised fluorescence-activated nuclei sorting for epigenomic analysis of cortical cell types

Barry Chioza, Stefania Policicchio, Joe Burrage, Georgina E. T. Blake, Rosemary A. Bamford, Alice Franklin, Darren Soanes, Philippa M. Wells, Ann Babtie, Marina Flores Payan, Jonathan P. Davies, Anthony Klokkaris, Emma M. Walker, Joy N. Ismail, Paulina Urbanaviciute, Sarah J. Marzi, Eilis Hannon, Jonathan Mill, Emma L. Dempster

published 06 Oct 2026

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CfDNA methylation profiling in blood following moderate-to-severe traumatic brain injury using brain cell type–enriched signatures: A pilot study

Shih-Han Kao, Larry N. Singh, Jonathan Starr, Firas H. Kobeissy, Claudia Robertson, Spyridoula Tsetsou, John B. Williamson, Damon G. Lamb, Amy K. Wagner, Zhifeng Kou, Robert D. Welch, Jose-Miguel Yamal, Luis Leon-Novelo, Richard Rubenstein, Kevin K. W. Wang, Todd J. Kilbaugh

published 06 Oct 2026

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Analysis of urinary kidney-specific cell-free DNA in preeclampsia

Vanessa C. Heron, John B. Whitlam, David H. Murray, Nicky Boulter, Peter Mount, Suet-Wan Choy, Marina Katerelos, Kathy Paizis

published 29 Sep 2026

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Uncovering the diagnostic potential of seminal fluid beyond fertility: cfDNA methylation analysis for the detection of clinically significant prostate cancer

Jennifer Geis, James F. Smith, Tara Maddala, Greg Thoreson, Kiarash Michel, Jed Kaminetsky, Laurence Belkoff, Stephanie Huang, Bailey Griscom, James C. Hart, Shellie Bench, Hamisha Ardalani, Laura Rivas-Yepes, Daniel Civello, Kim M. Clark-Langone

published 09 Sep 2026

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Characterization of DNA methylation in PBMCs and donor-matched iPSCs shows age-related methylation is reset during stem cell reprogramming

Xylena Reed, Cory A. Weller, Sara Saez-Atienzar, Alexandra Beilina, Sultana Solaiman, Makayla Portley, Mary Kaileh, Roshni Roy, Jinhui Ding, A. Zenobia Moore, D. Thad Whitaker, Bryan J. Traynor, Luigi Ferrucci, J. Raphael Gibbs, Sonja W. Scholz, Mark R. Cookson

published 08 Sep 2026

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Conserved gene- and network-level thermal memory intervals in two divergent perennial crucifers in nature

Yoshikazu Endo, Haruki Nishio, Oguchi Taichi, Kyoko Yamane, Victoria Faith Eseese, Clarissa Frances Frederica, Hiroshi Kudoh, Diana Mihaela Buzas

published 19 Aug 2026

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A comparative study of CDO1 promoter methylation in gastric cancer and H. pylori-associated chronic gastritis: Implications for diagnostic performance

Selin Kankaya, Metehan Karatas, Engin Hatipoglu, Nuray Kepil, Zulal Kaptan, Zeynep Caliskan, Matem Tuncdemir, Yildiz Dincer

published 12 Aug 2026

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Early DNA methylation at the NGFI-A binding site of the NR3C1 1F promoter predicts cognitive functions at age five: Evidence from the Parents as Teachers intervention in the ZEPPELIN study

Elena Silvia Gardini, Alex Neuhauser, Simone Schaub, Isabelle Kalkusch, Patsawee Rodcharoen, Ulrike Ehlert, Andrea Lanfranchi, Gustavo Turecki, Peter Klaver

published 20 Jul 2026

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Exploring DNA methylation profiles in the pathogenesis of human osteoporosis via whole-genome bisulfite sequencing

Yinyin Zhang, Guoying Wu, Jialu Hou, Yeling Zhong, Yukai Zhang, Shishuo Xiong, Zehua Guo, Ying Li

published 16 Jul 2026

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A role for nucleosome remodellers during resection of deprotected telomeres in yeast

Anja M. Deiser, Caitlyn Agar, Juan de Dios Barba Tena, Boris Pfander

published 10 Jul 2026

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A novel m7G RNA methylation-related signature associated with MAPK signaling pathways in acute ischemic stroke

Wei-Gang Gong, Jian-Wei Lou, Sen Yin, Fang-Pu Yu, Wei Wu

published 23 Jun 2026

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Unimodal vs. multimodal deep learning for non-invasive MGMT promoter methylation prediction in glioblastoma: A systematic evaluation on the BraTS 2021 dataset

Freddy Oulia, Philippe Charton, Muhammad Kabir, Fabrice Gardebien, Cédric Damour, Frederic Cadet

published 12 Jun 2026

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