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Cell death

High-throughput screening of drug libraries identifies a new synergistic drug combination for the treatment of retinoblastoma

Po-Jen Tseng, Irina L. Sinenko, Marc Chambon, Damiano Banfi, Santiago Zugbi, María Belén Cancela, Kseniya A. Glinkina, Gerardo Turcatti, Christina Stathopoulos, Paula Schaiquevich, Francis L. Munier, Paul J. Dyson

published 25 Feb 2026

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Comprehensive analysis of the potential effect and mechanism of pyroptosis-related genes in treatment-related myeloid tumors

Jing Cheng, Weiyue Fang, Hongxia Tan, Xiaoxia Zhan, Xiaohui Zhu

published 24 Feb 2026

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Mechanism of action of cisplatin on Na⁺/K⁺ ATPase of Caco-2 colon cells in vitro

Rida Mourad, Rawad Hodeify, Sawsan Kreydiyyeh

published 24 Feb 2026

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Rosuvastatin protects against oxLDL-induced endothelial cell oxidative stress and attenuates atherosclerotic plaque formation in ApoE^-/- mice through the NF-κB pathway

Yichen Wu, Jiaqi Ke, Jiaxin Lv, Chaowei Cao, Chunxian Zhou, Lili Wu, Qiyang Zhou

published 20 Feb 2026

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A live cell biosensor protocol for high-resolution screening of therapy-resistant cancer cells

Viral D. Oza, Colin S. Williams, Jessica S. Blackburn

published 17 Feb 2026

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FSTL1 promotes dendritic cell pyroptosis and immunosuppression in sepsis by inhibiting STING autophagy

Qiong Li, Hua Ling, Jingyi Li, Jinru Li, Wentao Duan, Lijun Guo, Xingui Dai

published 17 Feb 2026

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SHP2 improved Late-onset fetal growth restriction via modulating ROS/BRD4/PI3K/YAP/PIGF signaling induced angiogenesis

Fang Li, Yaqin Li, Wei Hao, Xuan Zhang, Xueyan Shen, Botao Yang, Wei Zhang, Liman Fu, Suyan Gu

published 13 Feb 2026

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Omics-aided design genome editing strategy for challenging human immortalized cell models

Patricia Mendoza-Garcia, Benjamin Keith, Markus Nordberg, Ella Quist, Cristina Ferrás, Ghaith M. Hamza, Ramy Elgendy, Stephanie Kay Ashenden, Jordi Chi, Natalie R. van Zuydam, Neil Hattersley, Xiang Zhang

published 12 Feb 2026

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Remdesivir may exacerbate ischemic acute kidney injury through molecular alterations in PGC-1α and apoptosis pathways: An in vivo study

Yasin Bagheri, Zahra Malekinejad, Seyyedeh Mina Hejazian, Abdollah Abdollahpour, Fatemeh Khajepour, Mohaddeseh Farahbod, Sama Ahmadi, Samira Matin, Sepideh Zununi Vahed

published 12 Feb 2026

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Reducing OGT and O-GlcNAcylation enhance the anticancer effects of oxaliplatin in SW620 metastatic colorectal cancer cells

Thirasak Bunsuk, Juthamard Chantaraamporn, Photsathorn Mutapat, Penchatr Diskul Na Ayudthaya, Daranee Chokchaichamnankit, Chantragan Srisomsap, Jisnuson Svasti, Voraratt Champattanachai

published 10 Feb 2026

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MicroRNA-488-3p-loaded engineered exosomes inhibit proliferation, migration and invasion of hepatocellular carcinoma by targeting SEC61G

Huijie Gao, Zhaobin He, Shengbiao Yang, Xiqiang Wang, Qisen Yan, Chao Gao, Naiqing Liu, Zhaoyang Zhang, Weibo Niu, Jun Niu, Cheng Peng

published 09 Feb 2026

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Integrated metabolomics and bioactivity analysis of new chrysanthemum cultivar petals: Insights into eye-protecting agents

Yifan Wang, Hedi Zhao, Gangqiang Dong, Dan Yang, Xiaofei Liu, Zhuyin Chen, Yanyan Su, Yan Liu, Jingjing Zhu, Jun Zhang, Jing Zhang, Sha Chen

published 09 Feb 2026

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Development of niosomal nanoparticles loaded with cisplatin and vorinostat combination for cancer therapy

Hazar Ali, Zainab Lafi, Naeem Shalan

published 06 Feb 2026

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