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Cell death

Omics-aided design genome editing strategy for challenging human immortalized cell models

Patricia Mendoza-Garcia, Benjamin Keith, Markus Nordberg, Ella Quist, Cristina Ferrás, Ghaith M. Hamza, Ramy Elgendy, Stephanie Kay Ashenden, Jordi Chi, Natalie R. van Zuydam, Neil Hattersley, Xiang Zhang

published 12 Feb 2026

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Remdesivir may exacerbate ischemic acute kidney injury through molecular alterations in PGC-1α and apoptosis pathways: An in vivo study

Yasin Bagheri, Zahra Malekinejad, Seyyedeh Mina Hejazian, Abdollah Abdollahpour, Fatemeh Khajepour, Mohaddeseh Farahbod, Sama Ahmadi, Samira Matin, Sepideh Zununi Vahed

published 12 Feb 2026

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Reducing OGT and O-GlcNAcylation enhance the anticancer effects of oxaliplatin in SW620 metastatic colorectal cancer cells

Thirasak Bunsuk, Juthamard Chantaraamporn, Photsathorn Mutapat, Penchatr Diskul Na Ayudthaya, Daranee Chokchaichamnankit, Chantragan Srisomsap, Jisnuson Svasti, Voraratt Champattanachai

published 10 Feb 2026

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MicroRNA-488-3p-loaded engineered exosomes inhibit proliferation, migration and invasion of hepatocellular carcinoma by targeting SEC61G

Huijie Gao, Zhaobin He, Shengbiao Yang, Xiqiang Wang, Qisen Yan, Chao Gao, Naiqing Liu, Zhaoyang Zhang, Weibo Niu, Jun Niu, Cheng Peng

published 09 Feb 2026

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Integrated metabolomics and bioactivity analysis of new chrysanthemum cultivar petals: Insights into eye-protecting agents

Yifan Wang, Hedi Zhao, Gangqiang Dong, Dan Yang, Xiaofei Liu, Zhuyin Chen, Yanyan Su, Yan Liu, Jingjing Zhu, Jun Zhang, Jing Zhang, Sha Chen

published 09 Feb 2026

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Development of niosomal nanoparticles loaded with cisplatin and vorinostat combination for cancer therapy

Hazar Ali, Zainab Lafi, Naeem Shalan

published 06 Feb 2026

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Extracts from Cordyceps cicadae and Hericium erinaceus promote the neurite outgrowth of retinal ganglion cells

Fang-Yi Chen, Chin-Chu Chen, Chuan-Chin Chiao

published 06 Feb 2026

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Quantitative and temporal analysis of autophagy: Differential Response to amino acid and glucose starvation

Katie R. Martin, Stephanie L. Celano, Jessica D. Guillaume, Ryan D. Sheldon, Russell G. Jones, Jeffrey P. MacKeigan

published 04 Feb 2026

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Drospirenone promotes apoptosis in ectopic but inhibits proliferation in eutopic human endometrial stromal cells

Thanyarat Wongwananuruk, Somsin Petyim, Pawitra Suwannalert, Kittima Tungprasertpol, Supatra Klaymook

published 30 Jan 2026

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Molecular remodeling of the myocardium in mice with melanocortin-4 receptor deletion before cardiac function impairment

Xiaomei Wang, Yuanmin Qi, Ziming Zhu, Caiqin Wang, Zhimin Zhang, Haocheng Jia, Linhui Xia, Kai Meng, Jinxiang Yuan

published 30 Jan 2026

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RUBCN as a novel prognostic biomarker and therapeutic target in breast cancer

Dong Dong Yang, Cheng Hao Liu, Sheng Qiu Jia, Ze Kuan Xue, Ming Ming Zhang, Rui Yang, Yong Zhou Huang, Xin Chun Zhao, Bao San Han, Sheng Dong Nie, Gui Lin Huang, Ji Xue Hou

published 27 Jan 2026

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Single-cell RNA-seq reveals the piperlongumine is a potential drug for ischemic stroke

Jinwei Li, Xiaosi Zhu, Yan Zhang, Zixia Xu, Yurui Zhuang, Liqi Chen, Yan Cao, Chuan Chang, Yao Lv

published 23 Jan 2026

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Periplaneta americana extract ameliorates recurrent oral ulcers in rats by enhancing the intestinal epithelial barrier and regulating gut microbiota

Kailing Li, Liping Yuan, Jingyu Zhang, Weijun Li, Guanhua Zhao, Zhongze Chen, Yongshou Yang, Zhengchun He, Peiyun Xiao

published 23 Jan 2026

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