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Carcinogenesis

A biologically constrained agent-based model of cancer stem cell dynamics with reinforcement learning-guided adaptive radiotherapy

Mina Lagzian, S. Ehsan Razavi, Reyhane Kardehi Moghaddam

WNK2 may promote ovarian cancer progression by upregulating POU5F1B

Fengjie Li, Yongqin Jia, [ ... ], Zhiqing Liang

Prediction of myeloid malignant cells in Fanconi anemia using machine learning

Luis A. Flores-Mejía, Pablo Siliceo, [ ... ], Alfredo Rodríguez

Unravelling the therapeutic potential of dual TGFβ-1 and CXCR4 inhibition in breast cancer using computational strategies

Burhan Ul Haq, Shazia Sofi, [ ... ], Manzoor Ahmad Mir

A protocol for using human genetic data to identify circulating protein level changes that are the causal consequence of cancer processes

Lisa M. Hobson, Richard M. Martin, [ ... ], Philip C. Haycock

N-glycosylation of NANOG regulates stemness and apoptosis in colon cancer cells

Yin Tian, Yu Zeng, [ ... ], Xin Zhang

In silico identification, high yielding isolation and in vitro validation of 6β-cinnamoyl-7β -hydroxyvouacapen – 5α - ol as a Wnt/β-catenin pathway targeted anti-cancer secondary metabolite of Caesalpinia pulcherrima

Nirwani N. Seneviratne, Tolulope P. Saliu, [ ... ], Sameera R. Samarakoon

STAG2 mutations in the normal colon induce upregulation of oncogenic pathways in neighbouring wildtype cells

Wei Ni Yew, Christopher James Dean, Dedrick Kok Hong Chan

The role of lncRNA SNHG15 in UV-induced DNA damage repair

Xin Zhang, Jiahui Lin, [ ... ], Yuming Wang

Frizzled 7 drives amplification of cancer stem-cell subpopulations and the aggressiveness and poor differentiation of human hepatocellular carcinoma

Anaïs Lopez, Alexia Paturel, [ ... ], Claude Caron de Fromentel

Role of c-Myc activating the transcription of PD-L1 in immune escape during benzene-induced malignant transformation of human lymphoblasts

Qihao Huang, Biyan Ye, [ ... ], Huanwen Tang

Integrative network toxicology and molecular docking reveal 4-Nonylphenol’s multifaceted mechanisms in breast cancer pathogenesis

Congli Jia, Fu Yang

Sex-dependent effects of a gestational ketogenic diet on offspring birth and lifespan

Sarah M. Zala, Renata Santos, [ ... ], Diana Zala

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