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Biophysics

A Heterozygous Deletion Mutation in the Cardiac Sodium Channel Gene SCN5A with Loss- and Gain-of-Function Characteristics Manifests as Isolated Conduction Disease, without Signs of Brugada or Long QT Syndrome

Sven Zumhagen, Marieke W. Veldkamp, [ ... ], Eric Schulze-Bahr

Ryanodine Receptors Selectively Interact with L Type Calcium Channels in Mouse Taste Cells

Michelle R. Rebello, Amanda B. Maliphol, Kathryn F. Medler

Putative Structural and Functional Coupling of the Mitochondrial BK_Ca Channel to the Respiratory Chain

Piotr Bednarczyk, Mariusz R. Wieckowski, [ ... ], Adam Szewczyk

Evaluation of SNP Data from the Malus Infinium Array Identifies Challenges for Genetic Analysis of Complex Genomes of Polyploid Origin

Michela Troggio, Nada Šurbanovski, [ ... ], Daniel James Sargent

Calpain-Mediated Processing of Adenylate Cyclase Toxin Generates a Cytosolic Soluble Catalytically Active N-Terminal Domain

Kepa B. Uribe, Aitor Etxebarria, César Martín, Helena Ostolaza

Predicting Drug-Target Interactions for New Drug Compounds Using a Weighted Nearest Neighbor Profile

Twan van Laarhoven, Elena Marchiori

Primary Ion Depletion Kinetics (PIDK) Studies as a New Tool for Investigating Chemical Ionization Fragmentation Reactions with PTR-MS

Erna Schuhfried, Tilmann D. Märk, Franco Biasioli

Whole Genome Association Studies of Residual Feed Intake and Related Traits in the Pig

Suneel K. Onteru, Danielle M. Gorbach, [ ... ], Max F. Rothschild

Native Pyroglutamation of Huwentoxin-IV: A Post-Translational Modification that Increases the Trapping Ability to the Sodium Channel

Mingqiang Rong, Zhigui Duan, [ ... ], Songping Liang

DISSECT Method Using PNA-LNA Clamp Improves Detection of EGFR T790m Mutation

Minakshi Guha, Elena Castellanos-Rizaldos, G. Mike Makrigiorgos

BDNF Depresses Excitability of Parvalbumin-Positive Interneurons through an M-Like Current in Rat Dentate Gyrus

Jose Luis Nieto-Gonzalez, Kimmo Jensen

β-Blockers and All-Cause Mortality in Adults with Episodes of Acute Bronchitis: An Observational Study

Frans H. Rutten, Rolf H. H. Groenwold, [ ... ], Arno W. Hoes

Pharmacologic Approach to Defective Protein Trafficking in the E637K-hERG Mutant with PD-118057 and Thapsigargin

Haiyan Mao, Xiaoli Lu, [ ... ], Jiangfang Lian

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