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Binding analysis

Vibegron shows high selectivity and potent agonist activity for β3-adrenoceptors, irrespective of receptor density

Shota Yamamoto, Hotaka Kusabuka, [ ... ], Takanobu Yamazaki

Inhibition of α-hemolysin activity of Staphylococcus aureus by theaflavin 3,3’-digallate

Anna Goc, Waldemar Sumera, Matthias Rath, Aleksandra Niedzwiecki

Is serotonin transporter brain binding associated with the cortisol awakening response? An independent non-replication

Juliane Conradi, Jonas E. Svensson, Søren V. Larsen, Vibe G. Frokjaer

Targeting Filamenting temperature-sensitive mutant Z (FtsZ) with bioactive phytoconstituents: An emerging strategy for antibacterial therapy

Bader Saud Alotaibi

Rapid and sensitive detection of gram-negative bacteria using surface-immobilized polymyxin B

Hyun-Jin Kang, Sang-Hoon Lee, [ ... ], Hee-Deung Park

Application of In vitro transcytosis models to brain targeted biologics

Kangwen Deng, Yifeng Lu, [ ... ], Andrew Goodearl

How ligands regulate the binding of PARP1 with DNA: Deciphering the mechanism at the molecular level

Kai Wang, Yizhou Wu, [ ... ], Shuya Sun

Single molecule studies characterize the kinetic mechanism of tetrameric p53 binding to different native response elements

Johannes P. Suwita, Calvin K. Voong, [ ... ], Jennifer F. Kugel

Global expression pattern of genes containing positively selected sites in European anchovy (Engraulis encrasicolus L.) may shed light on teleost reproduction

Vahap Eldem, Gökmen Zararsız, Melike Erkan

Analytical sameness methodology for the evaluation of structural, physicochemical, and biological characteristics of Armlupeg: A pegfilgrastim biosimilar case study

Arati Deshmukh, Rishank Goyal, [ ... ], Sanjay Tiwari

Selective DNA-binding of SP120 (rat ortholog of human hnRNP U) is mediated by arginine-glycine rich domain and modulated by RNA

Mary Miyaji, Shinji Kawano, [ ... ], Ken Tsutsui

Analytical comparability to evaluate impact of manufacturing changes of ARX788, an Anti-HER2 ADC in late-stage clinical development

Wayne Yu, Mysore P. Ramprasad, [ ... ], Ying Buechler

CCX559 is a potent, orally-administered small molecule PD-L1 inhibitor that induces anti-tumor immunity

Kathleen M. C. Sullivan, Marta Vilalta, [ ... ], Penglie Zhang

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