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Binding analysis

How ligands regulate the binding of PARP1 with DNA: Deciphering the mechanism at the molecular level

Kai Wang, Yizhou Wu, [ ... ], Shuya Sun

Single molecule studies characterize the kinetic mechanism of tetrameric p53 binding to different native response elements

Johannes P. Suwita, Calvin K. Voong, [ ... ], Jennifer F. Kugel

Global expression pattern of genes containing positively selected sites in European anchovy (Engraulis encrasicolus L.) may shed light on teleost reproduction

Vahap Eldem, Gökmen Zararsız, Melike Erkan

Analytical sameness methodology for the evaluation of structural, physicochemical, and biological characteristics of Armlupeg: A pegfilgrastim biosimilar case study

Arati Deshmukh, Rishank Goyal, [ ... ], Sanjay Tiwari

Selective DNA-binding of SP120 (rat ortholog of human hnRNP U) is mediated by arginine-glycine rich domain and modulated by RNA

Mary Miyaji, Shinji Kawano, [ ... ], Ken Tsutsui

Analytical comparability to evaluate impact of manufacturing changes of ARX788, an Anti-HER2 ADC in late-stage clinical development

Wayne Yu, Mysore P. Ramprasad, [ ... ], Ying Buechler

CCX559 is a potent, orally-administered small molecule PD-L1 inhibitor that induces anti-tumor immunity

Kathleen M. C. Sullivan, Marta Vilalta, [ ... ], Penglie Zhang

Anti-spike protein to determine SARS-CoV-2 antibody levels: Is there a specific threshold conferring protection in immunocompromised patients?

Philippe Halfon, Sylvie Jordana, [ ... ], Guillaume Penaranda

In silico elucidation of potential drug targets against oxygenase domain of Human eNOS Dysfunction

Abbeha Malik, Muhammad Nasir Iqbal, [ ... ], Sheikh Arslan Sehgal

Artemisinin suppresses aerobic glycolysis in thyroid cancer cells by downregulating HIF-1a, which is increased by the XIST/miR-93/HIF-1a pathway

Fei Yang, Jie Zhang, [ ... ], Jing Jin

Characterization of methylation profiles in spontaneous preterm birth placental villous tissue

Heather M. Brockway, Samantha L. Wilson, [ ... ], Helen N. Jones

Direct selection of functional fluorescent-protein antibody fusions by yeast display

Nileena Velappan, Fortunato Ferrara, [ ... ], Andrew R. M. Bradbury

Effect of acetic acid inactivation of SARS-CoV-2

Narayanappa Amruta, Nicholas J. Maness, [ ... ], Gregory Bix

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