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Binding analysis

Hyperosmolarity Invokes Distinct Anti-Inflammatory Mechanisms in Pulmonary Epithelial Cells: Evidence from Signaling and Transcription Layers

Franklin L. Wright, Fabia Gamboni, Ernest E. Moore, Trevor L. Nydam, Sanchayita Mitra, Christopher C. Silliman, Anirban Banerjee

published 05 Dec 2014

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Synthesis and Functional Characterization of Substituted Isoquinolinones as MT₂-Selective Melatoninergic Ligands

Yueqing Hu, King H. Chan, Xixin He, Maurice K. C. Ho, Yung H. Wong

published 05 Dec 2014

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Pharmacological and Behavioral Characterization of D-473, an Orally Active Triple Reuptake Inhibitor Targeting Dopamine, Serotonin and Norepinephrine Transporters

Aloke K. Dutta, Soumava Santra, Horrick Sharma, Chandrashekhar Voshavar, Liping Xu, Omar Mabrouk, Tamara Antonio, Maarten E. A. Reith

published 26 Nov 2014

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Influence of Nonenzymatic Posttranslational Modifications on Constitution, Oligomerization and Receptor Binding of S100A12

Kerstin Augner, Jutta Eichler, Wolfgang Utz, Monika Pischetsrieder

published 26 Nov 2014

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Structural and Functional Study of the GlnB22-Insulin Mutant Responsible for Maturity-Onset Diabetes of the Young

Květoslava Křížková, Václav Veverka, Lenka Maletínská, Rozálie Hexnerová, Andrzej M. Brzozowski, Jiří Jiráček, Lenka Žáková

published 25 Nov 2014

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Downregulation of hTERT: An Important As₂O₃ Induced Mechanism of Apoptosis in Myelodysplastic Syndrome

Weilai Xu, Yungui Wang, Hongyan Tong, Wenbin Qian, Jie Jin

published 21 Nov 2014

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A Biophysical Study with Carbohydrate Derivatives Explains the Molecular Basis of Monosaccharide Selectivity of the Pseudomonas aeruginosa Lectin LecB

Roman Sommer, Thomas E. Exner, Alexander Titz

published 21 Nov 2014

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Distinct Interactions with Cellular E-Cadherin of the Two Virulent Metalloproteinases Encoded by a Bacteroides fragilis Pathogenicity Island

Albert G. Remacle, Sergey A. Shiryaev, Alex Y. Strongin

published 20 Nov 2014

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Staphylococcus aureus Manganese Transport Protein C (MntC) Is an Extracellular Matrix- and Plasminogen-Binding Protein

Natália Salazar, Mónica Marcela Castiblanco-Valencia, Ludmila Bezerra da Silva, Íris Arantes de Castro, Denize Monaris, Hana Paula Masuda, Angela Silva Barbosa, Ana Paula Mattos Arêas

published 19 Nov 2014

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How Does Domain Replacement Affect Fibril Formation of the Rabbit/Human Prion Proteins

Xu Yan, Jun-Jie Huang, Zheng Zhou, Jie Chen, Yi Liang

published 17 Nov 2014

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Demonstration of a Direct Interaction between β₂-Adrenergic Receptor and Insulin Receptor by BRET and Bioinformatics

Maja Mandić, Luka Drinovec, Sanja Glisic, Nevena Veljkovic, Jane Nøhr, Milka Vrecl

published 17 Nov 2014

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Alzheimer's Therapeutics Targeting Amyloid Beta 1–42 Oligomers I: Abeta 42 Oligomer Binding to Specific Neuronal Receptors Is Displaced by Drug Candidates That Improve Cognitive Deficits

Nicholas J. Izzo, Agnes Staniszewski, Lillian To, Mauro Fa, Andrew F. Teich, Faisal Saeed, Harrison Wostein, Thomas Walko III, Anisha Vaswani, Meghan Wardius, Zanobia Syed, Jessica Ravenscroft, Kelsie Mozzoni, Colleen Silky, Courtney Rehak, Raymond Yurko, Patricia Finn, Gary Look, Gilbert Rishton, Hank Safferstein, Miles Miller, Conrad Johanson, Edward Stopa, Manfred Windisch, Birgit Hutter-Paier, Mehrdad Shamloo, Ottavio Arancio, Harry LeVine III, Susan M. Catalano

published 12 Nov 2014

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Analysis of Nidogen-1/Laminin γ1 Interaction by Cross-Linking, Mass Spectrometry, and Computational Modeling Reveals Multiple Binding Modes

Philip Lössl, Knut Kölbel, Dirk Tänzler, David Nannemann, Christian H. Ihling, Manuel V. Keller, Marian Schneider, Frank Zaucke, Jens Meiler, Andrea Sinz

published 11 Nov 2014

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