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Binding analysis

IGF1 and IGF2 specificities to the two insulin receptor isoforms are determined by insulin receptor amino acid 718

Mie Andersen, Dorte Nørgaard-Pedersen, [ ... ], Rita Slaaby

Non-canonical binding interactions of the RNA recognition motif (RRM) domains of P34 protein modulate binding within the 5S ribonucleoprotein particle (5S RNP)

Anyango D. Kamina, Noreen Williams

SPR-based fragment screening with neurotensin receptor 1 generates novel small molecule ligands

Sylwia Huber, Fabio Casagrande, [ ... ], Michael Hennig

Unveiling a novel transient druggable pocket in BACE-1 through molecular simulations: Conformational analysis and binding mode of multisite inhibitors

Ornella Di Pietro, Jordi Juárez-Jiménez, [ ... ], F. Javier Luque

A Sequence in the loop domain of hepatitis C virus E2 protein identified in silico as crucial for the selective binding to human CD81

Chun-Chun Chang, Hao-Jen Hsu, [ ... ], Je-Wen Liou

Citrullination only infrequently impacts peptide binding to HLA class II MHC

John Sidney, Stephane Becart, [ ... ], Alessandro Sette

Aromatic amino acids in the cellulose binding domain of Penicillium crustosum endoglucanase EGL1 differentially contribute to the cellulose affinity of the enzyme

Jiang-Ke Yang, Wei Xiong, [ ... ], Zheng-Gang Han

Molecular docking studies of 3-bromopyruvate and its derivatives to metabolic regulatory enzymes: Implication in designing of novel anticancer therapeutic strategies

Saveg Yadav, Shrish Kumar Pandey, [ ... ], Sukh Mahendra Singh

Specific blockade of Rictor-mTOR association inhibits mTORC2 activity and is cytotoxic in glioblastoma

Angelica Benavides-Serrato, Jihye Lee, [ ... ], Joseph Gera

Mini-G proteins: Novel tools for studying GPCRs in their active conformation

Rony Nehmé, Byron Carpenter, [ ... ], Christopher G. Tate

Comparison of cell-based assays for the identification and evaluation of competitive CXCR4 inhibitors

Anneleen Van Hout, Thomas D’huys, [ ... ], Tom Van Loy

In-depth study of DNA binding of Cys₂His₂ finger domains in testis zinc-finger protein

Chun-Chi Chou, Shu-Yi Wei, Yuan-Chao Lou, Chinpan Chen

Inhibition of prenylated KRAS in a lipid environment

Johanna M. Jansen, Charles Wartchow, [ ... ], Stephen Hardy

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