Lymphatic Filariasis is one of the significant NTDs, and if left untreated, it can lead to severe complications such as lymphedema. As a leading cause of disability, it results in restricted mobility, loss of income, impaired well-being and social stigma. Even after eliminating the condition in 2023, over 70 million people remain at risk in high-endemic areas of Bangladesh. Key challenges identified by Koly et al included lack of awareness, limited access to healthcare, and the financial burden of treatment.
Image Credit: Koly et al, 2025
Viewpoints
CREATE and CONNECT: Arboviruses at the intersection of research and community outreach
PLOS Neglected Tropical Diseases: published August 22, 2025 | https://doi.org/10.1371/journal.pntd.0013436
Reviews
The impact of Schistosoma haematobium hybridization on molecular diagnosis of schistosomiasis: A review with emphasis on female genital schistosomiasis
PLOS Neglected Tropical Diseases: published August 7, 2025 | https://doi.org/10.1371/journal.pntd.0013364
Radiological features of chronic pulmonary histoplasmosis: Easily mistaken for tuberculosis
PLOS Neglected Tropical Diseases: published August 8, 2025 | https://doi.org/10.1371/journal.pntd.0013219
The story of elimination of visceral leishmaniasis (kala-azar) in India—Challenges towards sustainment
PLOS Neglected Tropical Diseases: published August 19, 2025 | https://doi.org/10.1371/journal.pntd.0013321
Research Articles
Knowledge, attitudes, and practices towards prevention and control of neurocysticercosis-related epilepsy in Northern Tanzania: A cross-sectional healthcare professional-based study
PLOS Neglected Tropical Diseases: published August 1, 2025 | https://doi.org/10.1371/journal.pntd.0013275
Epidemiological monitoring survey to assess the impact of mass drug administration with triple-drug regimen in lymphatic filariasis elimination programme in an endemic district in Southern India
PLOS Neglected Tropical Diseases: published August 1, 2025 | https://doi.org/10.1371/journal.pntd.0013368
Comparative performance of a commercial and in-house Mp1p antigen-detecting enzyme immunoassay for the rapid diagnosis of talaromycosis
PLOS Neglected Tropical Diseases: published August 1, 2025 | https://doi.org/10.1371/journal.pntd.0013248
Phenotypic dichotomy in Crotalus durissus ruruima venom and potential consequences for clinical management of snakebite envenomations
PLOS Neglected Tropical Diseases: published August 1, 2025 | https://doi.org/10.1371/journal.pntd.0013296
Preclinical evaluation of the neutralising efficacy of three antivenoms against the venoms of the recently taxonomically partitioned E. ocellatus and E. romani
PLOS Neglected Tropical Diseases: published August 4, 2025 | https://doi.org/10.1371/journal.pntd.0013371
Mass drug administration for trachoma elimination in a pastoral conflict area in Baringo County, Kenya: A study on barriers to coverage and compliance
PLOS Neglected Tropical Diseases: published August 4, 2025 | https://doi.org/10.1371/journal.pntd.0013327
Functional genomics of trypanotolerant and trypanosusceptible cattle infected with Trypanosoma congolense across multiple time points and tissues
PLOS Neglected Tropical Diseases: published August 4, 2025 | https://doi.org/10.1371/journal.pntd.0012882
Multi-contrast machine learning improves schistosomiasis diagnostic performance
PLOS Neglected Tropical Diseases: published August 4, 2025 | https://doi.org/10.1371/journal.pntd.0012879
Tissue tropism, pathology, and pathogenesis of West Nile virus infection in saltwater crocodile (Crocodylus porosus)
PLOS Neglected Tropical Diseases: published August 4, 2025 | https://doi.org/10.1371/journal.pntd.0013385
Spatiotemporal distribution of newly diagnosed echinococcosis patients in Sichuan Province, China, 2013–2024
PLOS Neglected Tropical Diseases: published August 4, 2025 | https://doi.org/10.1371/journal.pntd.0013358
Cryptosporidium infection and associated factors among diarrheic children under five years of age in Eastern Ethiopia
PLOS Neglected Tropical Diseases: published August 5, 2025 | https://doi.org/10.1371/journal.pntd.0013386
Confirmation of a hyperendemic focus of porcine cysticercosis in Northern Uganda: Prevalence and risk factor analysis
PLOS Neglected Tropical Diseases: published August 5, 2025 | https://doi.org/10.1371/journal.pntd.0013313
Community risk of environmental-borne cystic echinococcosis transmission in South America: Results from the multistep cross-sectional and case-control PERITAS study
PLOS Neglected Tropical Diseases: published August 6, 2025 | https://doi.org/10.1371/journal.pntd.0013382
Research on health education and health promotion during the process of schistosomiasis elimination III new approaches for student health education
PLOS Neglected Tropical Diseases: published August 6, 2025 | https://doi.org/10.1371/journal.pntd.0013388
Factors associated with diagnostic delay and prognosis in hospitalized patients with strongyloidiasis in Okinawa, Japan
PLOS Neglected Tropical Diseases: published August 6, 2025 | https://doi.org/10.1371/journal.pntd.0013380
Global longitudinal strain as a predictor of outcomes in chronic Chagas´ cardiomyopathy
PLOS Neglected Tropical Diseases: published August 6, 2025 | https://doi.org/10.1371/journal.pntd.0012941
Barriers to surveillance and control of re-emergence of the Chagas disease vector Triatoma infestans in Arequipa, Peru
PLOS Neglected Tropical Diseases: published August 7, 2025 | https://doi.org/10.1371/journal.pntd.0013373
Recrudescence of transmission of onchocerciasis in some endemic communities in Kaduna State, Nigeria: What is the way forward?
PLOS Neglected Tropical Diseases: published August 7, 2025 | https://doi.org/10.1371/journal.pntd.0012495
Relative and attributable risks of neurological and perinatal adverse outcomes among children with and without prenatal Zika virus exposure in Northeast Brazil: A prospective cohort study (2015–2018)
PLOS Neglected Tropical Diseases: published August 8, 2025 | https://doi.org/10.1371/journal.pntd.0013344
Genetic analysis of Schistosoma mansoni in a low-transmission area in Brazil suggests population sharing between wild-hosts and humans and geographical isolation
PLOS Neglected Tropical Diseases: published August 11, 2025 | https://doi.org/10.1371/journal.pntd.0013379
Rabies control via co-creation: A model for sustainable one health interventions
PLOS Neglected Tropical Diseases: published August 11, 2025 | https://doi.org/10.1371/journal.pntd.0013350
Population genomics of Aedes albopictus across remote Pacific islands for genetic biocontrol considerations
PLOS Neglected Tropical Diseases: published August 11, 2025 | https://doi.org/10.1371/journal.pntd.0013414
Barriers to leprosy elimination in Bolivia: Exploring perspectives and experiences of medical professionals and leprosy patients–A phenomenological study
PLOS Neglected Tropical Diseases: published August 11, 2025 | https://doi.org/10.1371/journal.pntd.0013345
Development of an affordable multiplex quantitative RT-PCR assay for early detection and surveillance of Dengue, Chikungunya, and co-infections from clinical samples in resource-limited settings
PLOS Neglected Tropical Diseases: published August 11, 2025 | https://doi.org/10.1371/journal.pntd.0013250
Protective and therapeutic effects of Lactobacillus brevis PQ214320 and Bacillus subtilis PQ198038 Against experimental Trichinella Infection
PLOS Neglected Tropical Diseases: published August 11, 2025 | https://doi.org/10.1371/journal.pntd.0013331
Occurrence, risk factors and antimicrobial resistance of Campylobacter from poultry and humans in central Ethiopia: A one health approach
PLOS Neglected Tropical Diseases: published August 11, 2025 | https://doi.org/10.1371/journal.pntd.0012916
Advancing Mycobacterium leprae transmission research: Insights from the R2STOP fund
PLOS Neglected Tropical Diseases: published August 11, 2025 | https://doi.org/10.1371/journal.pntd.0013370
Assessing the effectiveness of the community participation approaches to improve access to mass drug administration for trachoma elimination in a pastoral conflict area of Baringo County, Kenya
PLOS Neglected Tropical Diseases: published August 11, 2025 | https://doi.org/10.1371/journal.pntd.0013408
Long-term clinical sequelae in severe fever with thrombocytopenia syndrome: A longitudinal cohort study
PLOS Neglected Tropical Diseases: published August 12, 2025 | https://doi.org/10.1371/journal.pntd.0013276
Putting behaviors into context for vector-borne diseases: Examining behaviors that may reduce exposure to disease vectors
PLOS Neglected Tropical Diseases: published August 12, 2025 | https://doi.org/10.1371/journal.pntd.0013365
Identification of arboviruses in mosquito populations in KwaZulu-Natal, South Africa and the first record of Wyeomyia mitchellii in the Old World
PLOS Neglected Tropical Diseases: published August 12, 2025 | https://doi.org/10.1371/journal.pntd.0013093
Social and healthcare-seeking experiences of people affected with lymphedema in Bangladesh
PLOS Neglected Tropical Diseases: published August 12, 2025 | https://doi.org/10.1371/journal.pntd.0013384
Perception of cattle owners towards risk of raw milk consumption for bovine tuberculosis transmission in Hosanna, Central Ethiopia: A community-based cross-sectional study
PLOS Neglected Tropical Diseases: published August 12, 2025 | https://doi.org/10.1371/journal.pntd.0013355
Elucidating the functional role of the novel BdP50 protein and extracellular vesicles in the human erythrocyte infection by Babesia divergens
PLOS Neglected Tropical Diseases: published August 13, 2025 | https://doi.org/10.1371/journal.pntd.0013401
Rift Valley fever virus and Coxiella burnetii infections among febrile patients, Eastern Ethiopia
PLOS Neglected Tropical Diseases: published August 13, 2025 | https://doi.org/10.1371/journal.pntd.0013375
Schistosoma japonicum in Ethiopia: Is there a need for tuning schistosomiasis surveillance in Africa?
PLOS Neglected Tropical Diseases: published August 13, 2025 | https://doi.org/10.1371/journal.pntd.0013425
Spatial and clinical epidemiology of spotted fever rickettsioses and ehrlichiosis, North Carolina, 2010–2019
PLOS Neglected Tropical Diseases: published August 13, 2025 | https://doi.org/10.1371/journal.pntd.0013406
Venomics of the Arabian saw-scaled viper (Echis coloratus) through transcriptome-guided proteomics and in vitro functional profiling
PLOS Neglected Tropical Diseases: published August 14, 2025 | https://doi.org/10.1371/journal.pntd.0013439
Global sociodemographic, clinical, and epidemiological profiling of patients with mycetoma: A systematic review
PLOS Neglected Tropical Diseases: published August 14, 2025 | https://doi.org/10.1371/journal.pntd.0013217
Development and application of a novel beta-tubulin genotyping tool reveals host-specific transmission cluster in Balantioides coli
PLOS Neglected Tropical Diseases: published August 14, 2025 | https://doi.org/10.1371/journal.pntd.0013426
Knowledge and attitude of populations on blackflies and onchocerciasis and participation in mass drug administration in first-line communities near Erin-Ijesha and Arinta waterfalls, Southwest Nigeria
PLOS Neglected Tropical Diseases: published August 14, 2025 | https://doi.org/10.1371/journal.pntd.0013411
Disruptions in gene interaction networks abolish host susceptibility to Trichostrongylus colubriformis infections in sheep
PLOS Neglected Tropical Diseases: published August 14, 2025 | https://doi.org/10.1371/journal.pntd.0013399
Classification of Trypanosoma brucei mammalian life cycle stages using Deep Learning Algorithms
PLOS Neglected Tropical Diseases: published August 14, 2025 | https://doi.org/10.1371/journal.pntd.0013298
Limited efficacy of cold and heat therapy as adjunctive treatments for local and functional outcomes of Bothrops atrox snakebite envenomation: A randomized clinical trial
PLOS Neglected Tropical Diseases: published August 14, 2025 | https://doi.org/10.1371/journal.pntd.0013423
Epidemiological, etiological, and serological characteristics of hand, foot, and mouth disease in Guizhou Province, Southwest China, from 2008 to 2023
PLOS Neglected Tropical Diseases: published August 18, 2025 | https://doi.org/10.1371/journal.pntd.0013394
Impact of climate change on the spread of fascioliasis into the extreme south of South America
PLOS Neglected Tropical Diseases: published August 18, 2025 | https://doi.org/10.1371/journal.pntd.0013433
Prevalence and risk factors of sheep and goats fasciolosis in Ethiopia: A systematic review and meta-analysis
PLOS Neglected Tropical Diseases: published August 18, 2025 | https://doi.org/10.1371/journal.pntd.0013074
A phase Ib/II clinical study to evaluate the safety and efficacy of topical Arnica tincture to treat non-complicated cutaneous leishmaniasis in Colombia
PLOS Neglected Tropical Diseases: published August 18, 2025 | https://doi.org/10.1371/journal.pntd.0013123
Dengue nowcasting in Brazil by combining official surveillance data and Google Trends information
PLOS Neglected Tropical Diseases: published August 18, 2025 | https://doi.org/10.1371/journal.pntd.0012501
“The Perfect Swarm” – Flooding across Northern Victoria leads to intensified mosquito breeding and subsequent re-emergence and transmission of Murray Valley encephalitis virus during the 2022-23 mosquito season
PLOS Neglected Tropical Diseases: published August 18, 2025 | https://doi.org/10.1371/journal.pntd.0013407
Burden of Shigella among children with diarrhea in the Americas: A systematic review and meta-analysis
PLOS Neglected Tropical Diseases: published August 18, 2025 | https://doi.org/10.1371/journal.pntd.0013393
The burden of rheumatic heart disease and issues affecting the provision of care in Malawi: A scoping review
PLOS Neglected Tropical Diseases: published August 19, 2025 | https://doi.org/10.1371/journal.pntd.0013400
Phylogenetic diversity and molecular evolution of Hantaan virus harbored by Apodemus chejuensis on Jeju Island, Republic of Korea, 2022–2023
PLOS Neglected Tropical Diseases: published August 19, 2025 | https://doi.org/10.1371/journal.pntd.0013459
Leprosy in skeletons from archaeological sites: A systematic review
PLOS Neglected Tropical Diseases: published August 19, 2025 | https://doi.org/10.1371/journal.pntd.0013374
Transmission models of Mycobacterium ulcerans: A systematic review
PLOS Neglected Tropical Diseases: published August 19, 2025 | https://doi.org/10.1371/journal.pntd.0013376
Prevalence of human T-cell leukemia virus type 1 associated inflammatory myopathies (HAIM) in Salvador, Brazil
PLOS Neglected Tropical Diseases: published August 20, 2025 | https://doi.org/10.1371/journal.pntd.0013409
Validation of the Brugia Test Plus to detect IgG4 antibodies in individuals from Belitung Timur, a Brugia malayi endemic area in Indonesia
PLOS Neglected Tropical Diseases: published August 20, 2025 | https://doi.org/10.1371/journal.pntd.0013449
Molecular characterization of zinc metalloproteinase Nas-14 from Trichinella spiralis and its participation in intestinal invasion
PLOS Neglected Tropical Diseases: published August 21, 2025 | https://doi.org/10.1371/journal.pntd.0013437
Genomic epidemiology of enteropathogenic Escherichia coli in southwestern Nigeria
PLOS Neglected Tropical Diseases: published August 22, 2025 | https://doi.org/10.1371/journal.pntd.0013442
Ambiguities in cutaneous leishmaniasis classification and the need for consensus: Experience from Ethiopia
PLOS Neglected Tropical Diseases: published August 22, 2025 | https://doi.org/10.1371/journal.pntd.0013458
Mathematical modeling of control strategies for the elimination of soil-transmitted helminthiases in Thailand
PLOS Neglected Tropical Diseases: published August 22, 2025 | https://doi.org/10.1371/journal.pntd.0013435
Epidemiological, temporal, and geographic trends of leptospirosis in the United States, 2014–2020
PLOS Neglected Tropical Diseases: published August 22, 2025 | https://doi.org/10.1371/journal.pntd.0013427
Inter-epidemic seroprevalence of Rift Valley fever virus and associated risk factors in humans in Eastern Rwanda
PLOS Neglected Tropical Diseases: published August 22, 2025 | https://doi.org/10.1371/journal.pntd.0013405
Dermal trypanosomes in seropositive suspects of gambiense human African trypanosomiasis in Côte d’Ivoire
PLOS Neglected Tropical Diseases: published August 25, 2025 | https://doi.org/10.1371/journal.pntd.0013027
Remapping parasite landscapes: Nationwide prevalence, intensity and risk factors of schistosomiasis and soil-transmitted helminthiasis in Rwanda
PLOS Neglected Tropical Diseases: published August 25, 2025 | https://doi.org/10.1371/journal.pntd.0013328
Preliminary screening of urinary host protein biomarkers for Schistosomiasis haematobium: A proteome profiling study identifying candidate diagnostic targets in school-aged children
PLOS Neglected Tropical Diseases: published August 25, 2025 | https://doi.org/10.1371/journal.pntd.0013429
Histoplasma capsulatum in wild mammals from Ecuador
PLOS Neglected Tropical Diseases: published August 25, 2025 | https://doi.org/10.1371/journal.pntd.0013410
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PLOS Neglected Tropical Diseases: published August 29, 2025 | https://doi.org/10.1371/journal.pntd.0012371
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PLOS Neglected Tropical Diseases: published August 29, 2025 | https://doi.org/10.1371/journal.pntd.0012191
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Correction
Correction: Correction: Schistosoma mansoni x S. haematobium hybrids frequently infecting sub-Saharan migrants in southeastern Europe: Egg DNA genotyping assessed by RD-PCR, sequencing and cloning
PLOS Neglected Tropical Diseases: published August 19, 2025 | https://doi.org/10.1371/journal.pntd.0013438
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Formal Comment
Re-evaluating a single-arm trial of favipiravir for severe fever with thrombocytopenia syndrome in Japan: A proposal to use real-world data as external controls
PLOS Neglected Tropical Diseases: published August 1, 2025 | https://doi.org/10.1371/journal.pntd.0013279