New thinking is required to improve feasibility and accessibility of diagnostics in remote settings where the burden of neglected tropical diseases is the greatest. This applies to anthrax, a zoonotic disease that remains a threat to the health and livelihoods of people across Africa, including pastoral communities in Tanzania’s Ngorongoro Conservation Area. Aminu (2020)
Image Credit: Dr. Tiziana Lembo
Editorial
A new Korean Research Investment for Global Health Technology (RIGHT) Fund to advance innovative neglected-disease technologies
PLOS Neglected Tropical Diseases: published September 3, 2020 | https://doi.org/10.1371/journal.pntd.0007956
Viewpoints
A bug’s life: Delving into the challenges of helminth microbiome studies
PLOS Neglected Tropical Diseases: published September 10, 2020 | https://doi.org/10.1371/journal.pntd.0008446
The SARS-CoV-2 crisis and its impact on neglected tropical diseases: Threat or opportunity?
PLOS Neglected Tropical Diseases: published September 21, 2020 | https://doi.org/10.1371/journal.pntd.0008680
The COVID-19 pandemic should not jeopardize dengue control
PLOS Neglected Tropical Diseases: published September 23, 2020 | https://doi.org/10.1371/journal.pntd.0008716
NTDs in the 2020s: An epic struggle of effective control tools versus the Anthropocene
PLOS Neglected Tropical Diseases: published September 24, 2020 | https://doi.org/10.1371/journal.pntd.0007872
Policy Platform
A case for adoption of continuous albendazole treatment regimen for human echinococcal infections
PLOS Neglected Tropical Diseases: published September 17, 2020 | https://doi.org/10.1371/journal.pntd.0008566
The use of serology for trachoma surveillance: Current status and priorities for future investigation
PLOS Neglected Tropical Diseases: published September 24, 2020 | https://doi.org/10.1371/journal.pntd.0008316
Reviews
The global distribution of actinomycetoma and eumycetoma
PLOS Neglected Tropical Diseases: published September 24, 2020 | https://doi.org/10.1371/journal.pntd.0008397
Drug metabolism and pharmacokinetics of praziquantel: A review of variable drug exposure during schistosomiasis treatment in human hosts and experimental models
PLOS Neglected Tropical Diseases: published September 25, 2020 | https://doi.org/10.1371/journal.pntd.0008649
Research Articles
Seroprevalence of antibodies against Chlamydia trachomatis and enteropathogens and distance to the nearest water source among young children in the Amhara Region of Ethiopia
PLOS Neglected Tropical Diseases: published September 2, 2020 | https://doi.org/10.1371/journal.pntd.0008647
Meta-analyses of Schistosoma japonicum infections in wild rodents across China over time indicates a potential challenge to the 2030 elimination targets
PLOS Neglected Tropical Diseases: published September 2, 2020 | https://doi.org/10.1371/journal.pntd.0008652
Community-based sero-prevalence of chikungunya and yellow fever in the South Omo Valley of Southern Ethiopia
PLOS Neglected Tropical Diseases: published September 3, 2020 | https://doi.org/10.1371/journal.pntd.0008549
Assessing dehydration status in dengue patients using urine colourimetry and mobile phone technology
PLOS Neglected Tropical Diseases: published September 3, 2020 | https://doi.org/10.1371/journal.pntd.0008562
Toward implementation of combined incompatible and sterile insect techniques for mosquito control: Optimized chilling conditions for handling Aedes albopictus male adults prior to release
PLOS Neglected Tropical Diseases: published September 3, 2020 | https://doi.org/10.1371/journal.pntd.0008561
A cost-analysis of conducting population-based prevalence surveys for the validation of the elimination of trachoma as a public health problem in Amhara, Ethiopia
PLOS Neglected Tropical Diseases: published September 3, 2020 | https://doi.org/10.1371/journal.pntd.0008401
Spatial spillover analysis of a cluster-randomized trial against dengue vectors in Trujillo, Venezuela
PLOS Neglected Tropical Diseases: published September 3, 2020 | https://doi.org/10.1371/journal.pntd.0008576
Introduction of Mycobacterium ulcerans disease in the Bankim Health District of Cameroon follows damming of the Mapé River
PLOS Neglected Tropical Diseases: published September 4, 2020 | https://doi.org/10.1371/journal.pntd.0008501
A complement component C1q-mediated mechanism of antibody-dependent enhancement of Ebola virus infection
PLOS Neglected Tropical Diseases: published September 4, 2020 | https://doi.org/10.1371/journal.pntd.0008602
Human exposure to zoonotic malaria vectors in village, farm and forest habitats in Sabah, Malaysian Borneo
PLOS Neglected Tropical Diseases: published September 4, 2020 | https://doi.org/10.1371/journal.pntd.0008617
Knowledge, attitudes, practices of/towards COVID 19 preventive measures and symptoms: A cross-sectional study during the exponential rise of the outbreak in Cameroon
PLOS Neglected Tropical Diseases: published September 4, 2020 | https://doi.org/10.1371/journal.pntd.0008700
Early immune suppression leads to uncontrolled mite proliferation and potent host inflammatory responses in a porcine model of crusted versus ordinary scabies
PLOS Neglected Tropical Diseases: published September 4, 2020 | https://doi.org/10.1371/journal.pntd.0008601
Biodistribution of degradable polyanhydride particles in Aedes aegypti tissues
PLOS Neglected Tropical Diseases: published September 8, 2020 | https://doi.org/10.1371/journal.pntd.0008365
Redefining enteroaggregative Escherichia coli (EAEC): Genomic characterization of epidemiological EAEC strains
PLOS Neglected Tropical Diseases: published September 8, 2020 | https://doi.org/10.1371/journal.pntd.0008613
Zika virus transmission by Brazilian Aedes aegypti and Aedes albopictus is virus dose and temperature-dependent
PLOS Neglected Tropical Diseases: published September 8, 2020 | https://doi.org/10.1371/journal.pntd.0008527
An agonist of the CXCR4 receptor accelerates the recovery from the peripheral neuroparalysis induced by Taipan snake envenomation
PLOS Neglected Tropical Diseases: published September 8, 2020 | https://doi.org/10.1371/journal.pntd.0008547
A smartphone microscopic method for simultaneous detection of (oo)cysts of Cryptosporidium and Giardia
PLOS Neglected Tropical Diseases: published September 8, 2020 | https://doi.org/10.1371/journal.pntd.0008560
Genetic evidence for the role of non-human primates as reservoir hosts for human schistosomiasis
PLOS Neglected Tropical Diseases: published September 8, 2020 | https://doi.org/10.1371/journal.pntd.0008538
Fasciola hepatica Extracellular Vesicles isolated from excretory-secretory products using a gravity flow method modulate dendritic cell phenotype and activity
PLOS Neglected Tropical Diseases: published September 8, 2020 | https://doi.org/10.1371/journal.pntd.0008626
Dengue infection modulates locomotion and host seeking in Aedes aegypti
PLOS Neglected Tropical Diseases: published September 10, 2020 | https://doi.org/10.1371/journal.pntd.0008531
Dynamics of serological responses to defined recombinant proteins during Schistosoma mansoni infection in mice before and after the treatment with praziquantel
PLOS Neglected Tropical Diseases: published September 11, 2020 | https://doi.org/10.1371/journal.pntd.0008518
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Wide range of G6PD activities found among ethnic groups of the Chittagong Hill Tracts, Bangladesh
PLOS Neglected Tropical Diseases: published September 14, 2020 | https://doi.org/10.1371/journal.pntd.0008697
Practical and effective diagnosis of animal anthrax in endemic low-resource settings
PLOS Neglected Tropical Diseases: published September 14, 2020 | https://doi.org/10.1371/journal.pntd.0008655
The impact of semen testing for Ebola virus RNA on sexual behavior of male Ebola survivors in Liberia
PLOS Neglected Tropical Diseases: published September 14, 2020 | https://doi.org/10.1371/journal.pntd.0008556
Population genomics of louping ill virus provide new insights into the evolution of tick-borne flaviviruses
PLOS Neglected Tropical Diseases: published September 14, 2020 | https://doi.org/10.1371/journal.pntd.0008133
Comparison of dengue case classification schemes and evaluation of biological changes in different dengue clinical patterns in a longitudinal follow-up of hospitalized children in Cambodia
PLOS Neglected Tropical Diseases: published September 14, 2020 | https://doi.org/10.1371/journal.pntd.0008603
Interaction of Signaling Lymphocytic Activation Molecule Family 1 (SLAMF1) receptor with Trypanosoma cruzi is strain-dependent and affects NADPH oxidase expression and activity
PLOS Neglected Tropical Diseases: published September 14, 2020 | https://doi.org/10.1371/journal.pntd.0008608
A systematic review of the untreated mortality of murine typhus
PLOS Neglected Tropical Diseases: published September 14, 2020 | https://doi.org/10.1371/journal.pntd.0008641
Identifying correlates of Guinea worm (Dracunculus medinensis) infection in domestic dog populations
PLOS Neglected Tropical Diseases: published September 14, 2020 | https://doi.org/10.1371/journal.pntd.0008620
Heterogeneity of dengue transmission in an endemic area of Colombia
PLOS Neglected Tropical Diseases: published September 14, 2020 | https://doi.org/10.1371/journal.pntd.0008122
The complex health seeking pathway of a human African trypanosomiasis patient in Côte d’Ivoire underlines the need of setting up passive surveillance systems
PLOS Neglected Tropical Diseases: published September 14, 2020 | https://doi.org/10.1371/journal.pntd.0008588
ISG15 overexpression compensates the defect of Crimean-Congo hemorrhagic fever virus polymerase bearing a protease-inactive ovarian tumor domain
PLOS Neglected Tropical Diseases: published September 15, 2020 | https://doi.org/10.1371/journal.pntd.0008610
Post-exposure prophylaxis (PEP) efficacy of rifampin, rifapentine, moxifloxacin, minocycline, and clarithromycin in a susceptible-subclinical model of leprosy
PLOS Neglected Tropical Diseases: published September 16, 2020 | https://doi.org/10.1371/journal.pntd.0008583
Addressing barriers of community participation and access to mass drug administration for lymphatic filariasis elimination in Coastal Kenya using a participatory approach
PLOS Neglected Tropical Diseases: published September 16, 2020 | https://doi.org/10.1371/journal.pntd.0008499
A comparison of three approaches for the discovery of novel tripartite attachment complex proteins in Trypanosoma brucei
PLOS Neglected Tropical Diseases: published September 16, 2020 | https://doi.org/10.1371/journal.pntd.0008568
Autochthonous leprosy in Spain: Has the transmission of Mycobacterium leprae stopped?
PLOS Neglected Tropical Diseases: published September 16, 2020 | https://doi.org/10.1371/journal.pntd.0008611
Knowledge, attitudes, and practices related to Coronavirus disease 2019 during the outbreak among workers in China: A large cross-sectional study
PLOS Neglected Tropical Diseases: published September 17, 2020 | https://doi.org/10.1371/journal.pntd.0008584
Long-Term Mosquito culture with SkitoSnack, an artificial blood meal replacement
PLOS Neglected Tropical Diseases: published September 17, 2020 | https://doi.org/10.1371/journal.pntd.0008591
Expanded genome-wide comparisons give novel insights into population structure and genetic heterogeneity of Leishmania tropica complex
PLOS Neglected Tropical Diseases: published September 18, 2020 | https://doi.org/10.1371/journal.pntd.0008684
Transcriptomic profiling of the digestive tract of the rat flea, Xenopsylla cheopis, following blood feeding and infection with Yersinia pestis
PLOS Neglected Tropical Diseases: published September 18, 2020 | https://doi.org/10.1371/journal.pntd.0008688
Impact of a 3-year mass drug administration pilot project for taeniasis control in Madagascar
PLOS Neglected Tropical Diseases: published September 18, 2020 | https://doi.org/10.1371/journal.pntd.0008653
Evaluation of ocular involvement in patients with Hansen’s disease
PLOS Neglected Tropical Diseases: published September 21, 2020 | https://doi.org/10.1371/journal.pntd.0008585
Cross-serotypically conserved epitope recommendations for a universal T cell-based dengue vaccine
PLOS Neglected Tropical Diseases: published September 21, 2020 | https://doi.org/10.1371/journal.pntd.0008676
Strengthening the Bolivian pharmacovigilance system: New surveillance strategies to improve care for Chagas disease and tuberculosis
PLOS Neglected Tropical Diseases: published September 21, 2020 | https://doi.org/10.1371/journal.pntd.0008370
Distribution of household disinfection kits during the 2014-2015 Ebola virus outbreak in Monrovia, Liberia: The MSF experience
PLOS Neglected Tropical Diseases: published September 21, 2020 | https://doi.org/10.1371/journal.pntd.0008539
Bayesian estimation of Lassa virus epidemiological parameters: Implications for spillover prevention using wildlife vaccination
PLOS Neglected Tropical Diseases: published September 21, 2020 | https://doi.org/10.1371/journal.pntd.0007920
Land cover affects microclimate and temperature suitability for arbovirus transmission in an urban landscape
PLOS Neglected Tropical Diseases: published September 21, 2020 | https://doi.org/10.1371/journal.pntd.0008614
Collocation of avian and mammal antibodies to develop a rapid and sensitive diagnostic tool for Russell's Vipers Snakebite
PLOS Neglected Tropical Diseases: published September 21, 2020 | https://doi.org/10.1371/journal.pntd.0008701
Epidemiologic and spatiotemporal trends of Zika Virus disease during the 2016 epidemic in Puerto Rico
PLOS Neglected Tropical Diseases: published September 21, 2020 | https://doi.org/10.1371/journal.pntd.0008532
An in-depth report of quality control on Kato-Katz and data entry in four clinical trials evaluating the efficacy of albendazole against soil-transmitted helminth infections
PLOS Neglected Tropical Diseases: published September 21, 2020 | https://doi.org/10.1371/journal.pntd.0008625
Efficacy and safety of praziquantel and dihydroartemisinin piperaquine combination for treatment and control of intestinal schistosomiasis: A randomized, non-inferiority clinical trial
PLOS Neglected Tropical Diseases: published September 23, 2020 | https://doi.org/10.1371/journal.pntd.0008619
Machine learning and dengue forecasting: Comparing random forests and artificial neural networks for predicting dengue burden at national and sub-national scales in Colombia
PLOS Neglected Tropical Diseases: published September 24, 2020 | https://doi.org/10.1371/journal.pntd.0008056
Feasibility of community-based control of tsetse: A pilot project using Tiny Targets in the Democratic Republic of Congo
PLOS Neglected Tropical Diseases: published September 24, 2020 | https://doi.org/10.1371/journal.pntd.0008696
Long term follow-up of Trypanosoma cruzi infection and Chagas disease manifestations in mice treated with benznidazole or posaconazole
PLOS Neglected Tropical Diseases: published September 24, 2020 | https://doi.org/10.1371/journal.pntd.0008726
Activity limitation and social participation restriction among leprosy patients in Boru Meda Hospital, Amhara Region, Ethiopia
PLOS Neglected Tropical Diseases: published September 24, 2020 | https://doi.org/10.1371/journal.pntd.0008702
Vector competence and feeding-excretion behavior of Triatoma rubrovaria (Blanchard, 1843) (Hemiptera: Reduviidae) infected with Trypanosoma cruzi TcVI
PLOS Neglected Tropical Diseases: published September 24, 2020 | https://doi.org/10.1371/journal.pntd.0008712
Discovery of repurposing drug candidates for the treatment of diseases caused by pathogenic free-living amoebae
PLOS Neglected Tropical Diseases: published September 24, 2020 | https://doi.org/10.1371/journal.pntd.0008353
Epidemiological models for predicting Ross River virus in Australia: A systematic review
PLOS Neglected Tropical Diseases: published September 24, 2020 | https://doi.org/10.1371/journal.pntd.0008621
Lentinan improved the efficacy of vaccine against Trichinella spiralis in an NLRP3 dependent manner
PLOS Neglected Tropical Diseases: published September 25, 2020 | https://doi.org/10.1371/journal.pntd.0008632
A first nation-wide assessment of soil-transmitted helminthiasis in Fijian primary schools, and factors associated with the infection, using a lymphatic filariasis transmission assessment survey as surveillance platform
PLOS Neglected Tropical Diseases: published September 25, 2020 | https://doi.org/10.1371/journal.pntd.0008511
Rapid detection of brucellosis using a quantum dot-based immunochromatographic test strip
PLOS Neglected Tropical Diseases: published September 25, 2020 | https://doi.org/10.1371/journal.pntd.0008557
Exposure to nanoceria impacts larval survival, life history traits and fecundity of Aedes aegypti
PLOS Neglected Tropical Diseases: published September 25, 2020 | https://doi.org/10.1371/journal.pntd.0008654
The impact of Worms and Ladders, an innovative health educational board game on Soil-Transmitted Helminthiasis control in Abeokuta, Southwest Nigeria
PLOS Neglected Tropical Diseases: published September 25, 2020 | https://doi.org/10.1371/journal.pntd.0008486
Impact of annual and semi-annual mass drug administration for Lymphatic Filariasis and Onchocerciasis on Hookworm Infection in Côte d’Ivoire
PLOS Neglected Tropical Diseases: published September 25, 2020 | https://doi.org/10.1371/journal.pntd.0008642
A single mutation (V64G) within the RING Domain of Z attenuates Junin virus
PLOS Neglected Tropical Diseases: published September 25, 2020 | https://doi.org/10.1371/journal.pntd.0008555
Proteomic and deep sequencing analysis of extracellular vesicles isolated from adult male and female Schistosoma japonicum
PLOS Neglected Tropical Diseases: published September 28, 2020 | https://doi.org/10.1371/journal.pntd.0008618
Leveraging multiple data types to estimate the size of the Zika epidemic in the Americas
PLOS Neglected Tropical Diseases: published September 28, 2020 | https://doi.org/10.1371/journal.pntd.0008640
Circulating genotypes of Leptospira in French Polynesia : An 9-year molecular epidemiology surveillance follow-up study
PLOS Neglected Tropical Diseases: published September 28, 2020 | https://doi.org/10.1371/journal.pntd.0008662
NOD2 receptor is crucial for protecting against the digestive form of Chagas disease
PLOS Neglected Tropical Diseases: published September 28, 2020 | https://doi.org/10.1371/journal.pntd.0008667
2020 Review and revision of the 2015 Darwin melioidosis treatment guideline; paradigm drift not shift
PLOS Neglected Tropical Diseases: published September 28, 2020 | https://doi.org/10.1371/journal.pntd.0008659
Surveillance of invasive Aedes mosquitoes along Swiss traffic axes reveals different dispersal modes for Aedes albopictus and Ae. japonicus
PLOS Neglected Tropical Diseases: published September 28, 2020 | https://doi.org/10.1371/journal.pntd.0008705
Dynamics of food sources, ecotypic distribution and Trypanosoma cruzi infection in Triatoma brasiliensis from the northeast of Brazil
PLOS Neglected Tropical Diseases: published September 28, 2020 | https://doi.org/10.1371/journal.pntd.0008735
Using affinity propagation clustering for identifying bacterial clades and subclades with whole-genome sequences of Francisella tularensis
PLOS Neglected Tropical Diseases: published September 29, 2020 | https://doi.org/10.1371/journal.pntd.0008018
Genomic loss in environmental and isogenic morphotype isolates of Burkholderia pseudomallei is associated with intracellular survival and plaque-forming efficiency
PLOS Neglected Tropical Diseases: published September 29, 2020 | https://doi.org/10.1371/journal.pntd.0008590
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PLOS Neglected Tropical Diseases: published September 30, 2020 | https://doi.org/10.1371/journal.pntd.0008657
Validation of the Micronutrient and Environmental Enteric Dysfunction Assessment Tool and evaluation of biomarker risk factors for growth faltering and vaccine failure in young Malian children
PLOS Neglected Tropical Diseases: published September 30, 2020 | https://doi.org/10.1371/journal.pntd.0008711
Corrections
Correction: Female genital schistosomiasis and HIV/AIDS: Reversing the neglect of girls and women
PLOS Neglected Tropical Diseases: published September 1, 2020 | https://doi.org/10.1371/journal.pntd.0008725
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Correction: Geographic and socioeconomic factors associated with leprosy treatment default: An analysis from the 100 Million Brazilian Cohort
PLOS Neglected Tropical Diseases: published September 1, 2020 | https://doi.org/10.1371/journal.pntd.0008723
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PLOS Neglected Tropical Diseases: published September 1, 2020 | https://doi.org/10.1371/journal.pntd.0008724
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Correction: Schistosoma species detection by environmental DNA assays in African freshwaters
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Formal Comment
The viewpoint by White and colleagues critiquing the evaluation of the safety and efficacy of mass chemotherapy for Taenia solium taeniasis is unsubstantiated
PLOS Neglected Tropical Diseases: published September 3, 2020 | https://doi.org/10.1371/journal.pntd.0008592