February 2019

Severe tungiasis at the sole of the foot with dozens of embedded sand fleas in different stages of development. Miller, et al. (2019)

Image Credit: Hollman Miller

Editorial

PLOS Neglected Tropical Diseases 2018 Reviewer and Editorial Board Thank You

PLOS Neglected Tropical Diseases: published February 27, 2019 | https://doi.org/10.1371/journal.pntd.0007252

Policy Platform

Strategy for a globally coordinated response to a priority neglected tropical disease: Snakebite envenoming

David J. Williams, Mohd Abul Faiz, Bernadette Abela-Ridder, Stuart Ainsworth, Tommaso C. Bulfone, Andrea D. Nickerson, Abdulrazaq G. Habib, Thomas Junghanss, Hui Wen Fan, Michael Turner, Robert A. Harrison, David A. Warrell

PLOS Neglected Tropical Diseases: published February 21, 2019 | https://doi.org/10.1371/journal.pntd.0007059

Historical Profiles and Perspectives

The separation of trypanosomes from blood by anion exchange chromatography: From Sheila Lanham’s discovery 50 years ago to a gold standard for sleeping sickness diagnosis

Veerle Lejon, Philippe Büscher, Romaric Nzoumbou-Boko, Géraldine Bossard, Vincent Jamonneau, Bruno Bucheton, Philippe Truc, Jean-Loup Lemesre, Philippe Solano, Philippe Vincendeau

PLOS Neglected Tropical Diseases: published February 28, 2019 | https://doi.org/10.1371/journal.pntd.0007051

From Innovation to Application

A modified approach to recover and enumerate Ascaris ova in wastewater and sludge

Vivek B. Ravindran, Aravind Surapaneni, Nicholas D. Crosbie, Jonathan Schmidt, Esmaeil Shahsavari, Nagalakshmi Haleyur, Sarvesh K. Soni, Andrew S. Ball

PLOS Neglected Tropical Diseases: published February 21, 2019 | https://doi.org/10.1371/journal.pntd.0007020

Social media and control of soil-transmitted helminthiasis in Bhutan

Sangay Thinley, Kencho Namgyal, Antonio Montresor

PLOS Neglected Tropical Diseases: published February 28, 2019 | https://doi.org/10.1371/journal.pntd.0007102

Reviews

Strategies to increase adoption of animal vaccines by smallholder farmers with focus on neglected diseases and marginalized populations

Meritxell Donadeu, Nick Nwankpa, Bernadette Abela-Ridder, Baptiste Dungu

PLOS Neglected Tropical Diseases: published February 7, 2019 | https://doi.org/10.1371/journal.pntd.0006989

The complexities and challenges of preventing and treating nontuberculous mycobacterial diseases

Susan L. Baldwin, Sasha E. Larsen, Diane Ordway, Gail Cassell, Rhea N. Coler

PLOS Neglected Tropical Diseases: published February 14, 2019 | https://doi.org/10.1371/journal.pntd.0007083

The ecological dynamics of hantavirus diseases: From environmental variability to disease prevention largely based on data from China

Huaiyu Tian, Nils Chr. Stenseth

PLOS Neglected Tropical Diseases: published February 21, 2019 | https://doi.org/10.1371/journal.pntd.0006901

Research Articles

Identification of French Guiana sand flies using MALDI-TOF mass spectrometry with a new mass spectra library

Agathe Chavy, Cécile Nabet, Anne Cécile Normand, Arthur Kocher, Marine Ginouves, Ghislaine Prévot, Thiago Vasconcelos dos Santos, Magalie Demar, Renaud Piarroux, Benoît de Thoisy

PLOS Neglected Tropical Diseases: published February 1, 2019 | https://doi.org/10.1371/journal.pntd.0007031

Rapid detection of Mycobacterium ulcerans with isothermal recombinase polymerase amplification assay

Michael Frimpong, Hubert Senanu Ahor, Ahmed Abd El Wahed, Bernadette Agbavor, Francisca Naana Sarpong, Kenneth Laing, Mark Wansbrough-Jones, Richard Odame Phillips

PLOS Neglected Tropical Diseases: published February 1, 2019 | https://doi.org/10.1371/journal.pntd.0007155

Genomic instability at the locus of sterol C24-methyltransferase promotes amphotericin B resistance in Leishmania parasites

Andrew W. Pountain, Stefan K. Weidt, Clément Regnault, Paul A. Bates, Anne M. Donachie, Nicholas J. Dickens, Michael P. Barrett

PLOS Neglected Tropical Diseases: published February 4, 2019 | https://doi.org/10.1371/journal.pntd.0007052

Experimental Zika virus infection of Jamaican fruit bats (Artibeus jamaicensis) and possible entry of virus into brain via activated microglial cells

Ashley Malmlov, Collin Bantle, Tawfik Aboellail, Kaitlyn Wagner, Corey L. Campbell, Miles Eckley, Nunya Chotiwan, Rebekah C. Gullberg, Rushika Perera, Ronald Tjalkens, Tony Schountz

PLOS Neglected Tropical Diseases: published February 4, 2019 | https://doi.org/10.1371/journal.pntd.0007071

Comparative fitness of West Nile virus isolated during California epidemics

Gabriella Worwa, Andra A. Hutton, Aaron C. Brault, William K. Reisen

PLOS Neglected Tropical Diseases: published February 4, 2019 | https://doi.org/10.1371/journal.pntd.0007135

Water-induced strong protection against acute exposure to low subzero temperature of adult Aedes albopictus

Meichun Zhang, Dongjing Zhang, Yongjun Li, Qiang Sun, Qin Li, Yali Fan, Yu Wu, Zhiyong Xi, Xiaoying Zheng

PLOS Neglected Tropical Diseases: published February 4, 2019 | https://doi.org/10.1371/journal.pntd.0007139

The validity of diagnostic cut-offs for commercial and in-house scrub typhus IgM and IgG ELISAs: A review of the evidence

Kartika Saraswati, Meghna Phanichkrivalkosil, Nicholas P. J. Day, Stuart D. Blacksell

PLOS Neglected Tropical Diseases: published February 4, 2019 | https://doi.org/10.1371/journal.pntd.0007158

Reprogramming of Trypanosoma cruzi metabolism triggered by parasite interaction with the host cell extracellular matrix

Eliciane C. Mattos, Gisele Canuto, Nubia C. Manchola, Rubens D. M. Magalhães, Thomas W. M. Crozier, Douglas J. Lamont, Marina F. M. Tavares, Walter Colli, Michael A. J. Ferguson, Maria Júlia M. Alves

PLOS Neglected Tropical Diseases: published February 6, 2019 | https://doi.org/10.1371/journal.pntd.0007103

Protective immunity by an engineered DNA vaccine for Mayaro virus

Hyeree Choi, Sagar B. Kudchodkar, Emma L. Reuschel, Kanika Asija, Piyush Borole, Michelle Ho, Krzysztof Wojtak, Charles Reed, Stephanie Ramos, Nathen E. Bopp, Patricia V. Aguilar, Scott C. Weaver, J. Joseph Kim, Laurent Humeau, Pablo Tebas, David B. Weiner, Kar Muthumani

PLOS Neglected Tropical Diseases: published February 7, 2019 | https://doi.org/10.1371/journal.pntd.0007042

Very severe tungiasis in Amerindians in the Amazon lowland of Colombia: A case series

Hollman Miller, Jovana Ocampo, Alvaro Ayala, Julian Trujillo, Hermann Feldmeier

PLOS Neglected Tropical Diseases: published February 7, 2019 | https://doi.org/10.1371/journal.pntd.0007068

Knowledge, attitudes and practices with regard to schistosomiasis prevention and control: Two cross-sectional household surveys before and after a Community Dialogue intervention in Nampula province, Mozambique

Christian Rassi, Sandrine Martin, Kirstie Graham, Monica Anna de Cola, Celine Christiansen-Jucht, Lauren E. Smith, Ercílio Jive, Anna E. Phillips, James N. Newell, Marilia Massangaie

PLOS Neglected Tropical Diseases: published February 7, 2019 | https://doi.org/10.1371/journal.pntd.0007138

Inward rectifier potassium (Kir) channels mediate salivary gland function and blood feeding in the lone star tick, Amblyomma americanum

Zhilin Li, Kevin R. Macaluso, Lane D. Foil, Daniel R. Swale

PLOS Neglected Tropical Diseases: published February 7, 2019 | https://doi.org/10.1371/journal.pntd.0007153

Serological evidence of infection with dengue and Zika viruses in horses on French Pacific Islands

Cécile Beck, Isabelle Leparc-Goffart, Denise Desoutter, Estelle Debergé, Hervé Bichet, Steeve Lowenski, Marine Dumarest, Gaelle Gonzalez, Camille Migné, Jessica Vanhomwegen, Stéphan Zientara, Benoit Durand, Sylvie Lecollinet

PLOS Neglected Tropical Diseases: published February 7, 2019 | https://doi.org/10.1371/journal.pntd.0007162

Evaluation of a class of isatinoids identified from a high-throughput screen of human kinase inhibitors as anti-Sleeping Sickness agents

Dana M. Klug, Rosario Diaz-Gonzalez, Guiomar Pérez-Moreno, Gloria Ceballos-Pérez, Raquel García-Hernández, Veronica Gomez-Pérez, Luis Miguel Ruiz-Pérez, Domingo I. Rojas-Barros, Francisco Gamarro, Dolores González-Pacanowska, María S. Martínez-Martínez, Pilar Manzano, Lori Ferrins, Conor R. Caffrey, Miguel Navarro, Michael P. Pollastri

PLOS Neglected Tropical Diseases: published February 8, 2019 | https://doi.org/10.1371/journal.pntd.0007129

Etiology and severity of diarrheal diseases in infants at the semiarid region of Brazil: A case-control study

Aldo A. M. Lima, Domingos B. Oliveira, Josiane S. Quetz, Alexandre Havt, Mara M. G. Prata, Ila F. N. Lima, Alberto M. Soares, José Q. Filho, Noélia L. Lima, Pedro H. Q. S. Medeiros, Ana K. S. Santos, Herlice N. Veras, Rafhaella N. D. G. Gondim, Rafaela C. Pankov, Mariana D. Bona, Francisco A. P. Rodrigues, Renato A. Moreira, Ana C. O. M. Moreira, Marcelo Bertolini, Luciana R. Bertolini, Vicente J. F. Freitas, Eric R. Houpt, Richard L. Guerrant

PLOS Neglected Tropical Diseases: published February 8, 2019 | https://doi.org/10.1371/journal.pntd.0007154

Comparing the performance of urine and copro-antigen detection in evaluating Opisthorchis viverrini infection in communities with different transmission levels in Northeast Thailand

Chanika Worasith, Chompunoot Wangboon, Kunyarat Duenngai, Nadda Kiatsopit, Kulthida Kopolrat, Anchalee Techasen, Jiraporn Sithithaworn, Narong Khuntikeo, Watcharin Loilome, Nisana Namwat, Puangrat Yongvanit, Elizabeth J. Carlton, Paiboon Sithithaworn

PLOS Neglected Tropical Diseases: published February 8, 2019 | https://doi.org/10.1371/journal.pntd.0007186

Detection of Zika virus in mouse mammary gland and breast milk

Jose Angel Regla-Nava, Karla M. Viramontes, Teodora Vozdolska, Anh-Thy Huynh, Tom Villani, Graeme Gardner, Michael Johnson, Pamela J. Ferro, Sujan Shresta, Kenneth Kim

PLOS Neglected Tropical Diseases: published February 11, 2019 | https://doi.org/10.1371/journal.pntd.0007080

Acceptability of Aedes aegypti blood feeding on dengue virus-infected human volunteers for vector competence studies in Iquitos, Peru

Amy C. Morrison, Julia Schwarz, Kanya C. Long, Jhonny Cordova, Jennifer E. Rios, W. Lorena Quiroz, S. Alfonso Vizcarra, Robert D. Hontz, Thomas W. Scott, Louis Lambrechts, Valerie A. Paz Soldan

PLOS Neglected Tropical Diseases: published February 11, 2019 | https://doi.org/10.1371/journal.pntd.0007090

The safety and efficacy of miltefosine in the long-term treatment of post-kala-azar dermal leishmaniasis in South Asia – A review and meta-analysis

Joyce Pijpers, Margriet L. den Boer, Dirk R. Essink, Koert Ritmeijer

PLOS Neglected Tropical Diseases: published February 11, 2019 | https://doi.org/10.1371/journal.pntd.0007173

Effect of a sanitation intervention on soil-transmitted helminth prevalence and concentration in household soil: A cluster-randomized controlled trial and risk factor analysis

Lauren Steinbaum, John Mboya, Ryan Mahoney, Sammy M. Njenga, Clair Null, Amy J. Pickering

PLOS Neglected Tropical Diseases: published February 11, 2019 | https://doi.org/10.1371/journal.pntd.0007180

Genetic evidence of Coxiella burnetii infection in acute febrile illnesses in Iran

Saber Esmaeili, Ashraf Mohabati Mobarez, Mohammad Khalili, Ehsan Mostafavi, Pardis Moradnejad

PLOS Neglected Tropical Diseases: published February 11, 2019 | https://doi.org/10.1371/journal.pntd.0007181

Vector competence of biting midges and mosquitoes for Shuni virus

Tim W. R. Möhlmann, Judith Oymans, Paul J. Wichgers Schreur, Constantianus J. M. Koenraadt, Jeroen Kortekaas, Chantal B. F. Vogels

PLOS Neglected Tropical Diseases: published February 12, 2019 | https://doi.org/10.1371/journal.pntd.0006609

Feasibility of feeding Aedes aegypti mosquitoes on dengue virus-infected human volunteers for vector competence studies in Iquitos, Peru

Kanya C. Long, Juan Sulca, Isabel Bazan, Helvio Astete, Hugo L. Jaba, Crystyan Siles, Claudine Kocher, Stalin Vilcarromero, Julia Schwarz, Karin S. Escobedo-Vargas, Fanny Castro-Llanos, Leslye Angulo, Guadalupe Flores, Cesar Ramal-Asayag, Eric S. Halsey, Robert D. Hontz, Valerie A. Paz-Soldan, Thomas W. Scott, Louis Lambrechts, Amy C. Morrison

PLOS Neglected Tropical Diseases: published February 12, 2019 | https://doi.org/10.1371/journal.pntd.0007116

Potential for sylvatic and urban Aedes mosquitoes from Senegal to transmit the new emerging dengue serotypes 1, 3 and 4 in West Africa

Alioune Gaye, Eryu Wang, Nikos Vasilakis, Hilda Guzman, Diawo Diallo, Cheikh Talla, Yamar Ba, Ibrahima Dia, Scott C. Weaver, Mawlouth Diallo

PLOS Neglected Tropical Diseases: published February 13, 2019 | https://doi.org/10.1371/journal.pntd.0007043

Maternal Leishmania infantum infection status has significant impact on leishmaniasis in offspring

Angela J. Toepp, Carolyne Bennett, Benjamin Scott, Reid Senesac, Jacob J. Oleson, Christine A. Petersen

PLOS Neglected Tropical Diseases: published February 13, 2019 | https://doi.org/10.1371/journal.pntd.0007058

A simple score to predict severe leptospirosis

Simon Smith, Brendan J. Kennedy, Alexis Dermedgoglou, Suzanne S. Poulgrain, Matthew P. Paavola, Tarryn L. Minto, Michael Luc, Yu-Hsuan Liu, Josh Hanson

PLOS Neglected Tropical Diseases: published February 13, 2019 | https://doi.org/10.1371/journal.pntd.0007205

Potential of Aedes albopictus to cause the emergence of arboviruses in Morocco

Fadila Amraoui, Wiem Ben Ayed, Yoann Madec, Chafika Faraj, Oumnia Himmi, Ameur Btissam, Mhammed Sarih, Anna-Bella Failloux

PLOS Neglected Tropical Diseases: published February 14, 2019 | https://doi.org/10.1371/journal.pntd.0006997

Potential public health benefits from cat eradications on islands

Luz A. de Wit, Donald A. Croll, Bernie Tershy, Dolores Correa, Hector Luna-Pasten, Paulo Quadri, A. Marm Kilpatrick

PLOS Neglected Tropical Diseases: published February 14, 2019 | https://doi.org/10.1371/journal.pntd.0007040

A chronic bioluminescent model of experimental visceral leishmaniasis for accelerating drug discovery

Raquel Álvarez-Velilla, Maria del Camino Gutiérrez-Corbo, Carmen Punzón, Maria Yolanda Pérez-Pertejo, Rafael Balaña-Fouce, Manuel Fresno, Rosa María Reguera

PLOS Neglected Tropical Diseases: published February 14, 2019 | https://doi.org/10.1371/journal.pntd.0007133

Effect of Schistosoma mansoni infection and its treatment on antibody responses to measles catch-up immunisation in pre-school children: A randomised trial

Robert Tweyongyere, Beatrice R. Nassanga, Allan Muhwezi, Matthew Odongo, Swaib A. Lule, Rebecca N. Nsubuga, Emily L. Webb, Stephen C. Cose, Alison M. Elliott

PLOS Neglected Tropical Diseases: published February 14, 2019 | https://doi.org/10.1371/journal.pntd.0007157

Renal and vascular effects of kallikrein inhibition in a model of Lonomia obliqua venom-induced acute kidney injury

Markus Berger, João Alfredo de Moraes, Walter Orlando Beys-da-Silva, Lucélia Santi, Paula Barros Terraciano, David Driemeier, Elizabeth Obino Cirne-Lima, Eduardo Pandolfi Passos, Maria Aparecida Ribeiro Vieira, Thereza Christina Barja-Fidalgo, Jorge Almeida Guimarães

PLOS Neglected Tropical Diseases: published February 14, 2019 | https://doi.org/10.1371/journal.pntd.0007197

Soil-transmitted helminth reinfection four and six months after mass drug administration: results from the delta region of Myanmar

Julia C. Dunn, Alison A. Bettis, Nay Yee Wyine, Aye Moe Moe Lwin, Aung Tun, Nay Soe Maung, Roy M. Anderson

PLOS Neglected Tropical Diseases: published February 15, 2019 | https://doi.org/10.1371/journal.pntd.0006591

Antibody responses to Plasmodium vivax Duffy binding and Erythrocyte binding proteins predict risk of infection and are associated with protection from clinical Malaria

Wen-Qiang He, Ahmad Rushdi Shakri, Rukmini Bhardwaj, Camila T. França, Danielle I. Stanisic, Julie Healer, Benson Kiniboro, Leanne J. Robinson, Micheline Guillotte-Blisnick, Christèle Huon, Peter Siba, Alan Cowman, Christopher L. King, Wai-Hong Tham, Chetan E. Chitnis, Ivo Mueller

PLOS Neglected Tropical Diseases: published February 15, 2019 | https://doi.org/10.1371/journal.pntd.0006987

Prevalence of Wēnzhōu virus in small mammals in Yunnan Province, China

Jinxia Wang, Xinglou Yang, Haizhou Liu, Li Wang, Jihua Zhou, Xi Han, Yan Zhu, Weihong Yang, Hong Pan, Yunzhi Zhang, Zhengli Shi

PLOS Neglected Tropical Diseases: published February 15, 2019 | https://doi.org/10.1371/journal.pntd.0007049

Spatio-temporal characterization of Trypanosoma cruzi infection and discrete typing units infecting hosts and vectors from non-domestic foci of Chile

Camila Ihle-Soto, Eduardo Costoya, Juana P. Correa, Antonella Bacigalupo, Berenice Cornejo-Villar, Viviana Estadella, Aldo Solari, Sylvia Ortiz, Héctor J. Hernández, Carezza Botto-Mahan, David E. Gorla, Pedro E. Cattan

PLOS Neglected Tropical Diseases: published February 15, 2019 | https://doi.org/10.1371/journal.pntd.0007170

Inadequate knowledge about snakebite envenoming symptoms and application of harmful first aid methods in the community in high snakebite incidence areas of Myanmar

Mohammad Afzal Mahmood, Dale Halliday, Robert Cumming, Khin Thida Thwin, Mya Myitzu, Julian White, Sam Alfred, David A. Warrell, David Bacon, Win Naing, Htay Aung, Myat Myat Thein, Nyein Nyein Chit, Sara Serhal, Myat Thet Nwe, Pyae Phyo Aung, Chen Au Peh

PLOS Neglected Tropical Diseases: published February 15, 2019 | https://doi.org/10.1371/journal.pntd.0007171

Osseous cystic echinococcosis: A case series study at a referral unit in Spain

Begoña Monge-Maillo, María Olmedo Samperio, José Antonio Pérez-Molina, Francesca Norman, Carla Ruth Mejía, Sandra Chamorro Tojeiro, Rogelio López-Vélez

PLOS Neglected Tropical Diseases: published February 19, 2019 | https://doi.org/10.1371/journal.pntd.0007006

Spontaneous healing of Mycobacterium ulcerans disease in Australian patients

Daniel P. O’Brien, Adrian Murrie, Peter Meggyesy, Jonathan Priestley, Avinash Rajcoomar, Eugene Athan

PLOS Neglected Tropical Diseases: published February 19, 2019 | https://doi.org/10.1371/journal.pntd.0007178

Parasite specific 7SL-derived small RNA is an effective target for diagnosis of active trypanosomiasis infection

Stephen M. Chiweshe, Pieter C. Steketee, Siddharth Jayaraman, Edith Paxton, Kyriaki Neophytou, Heidi Erasmus, Michel Labuschagne, Anneli Cooper, Annette MacLeod, Finn E. Grey, Liam J. Morrison

PLOS Neglected Tropical Diseases: published February 19, 2019 | https://doi.org/10.1371/journal.pntd.0007189

A survey on Mycobacterium ulcerans in Mosquitoes and March flies captured from endemic areas of Northern Queensland, Australia

Avishek Singh, William John Hannan McBride, Brenda Govan, Mark Pearson, Scott A. Ritchie

PLOS Neglected Tropical Diseases: published February 21, 2019 | https://doi.org/10.1371/journal.pntd.0006745

Profile of the tprK gene in primary syphilis patients based on next-generation sequencing

Dan Liu, Man-Li Tong, Xi Luo, Li-Li Liu, Li-Rong Lin, Hui-Lin Zhang, Yong Lin, Jian-Jun Niu, Tian-Ci Yang

PLOS Neglected Tropical Diseases: published February 21, 2019 | https://doi.org/10.1371/journal.pntd.0006855

Mother-to-child transmission and gestational syphilis: Spatial-temporal epidemiology and demographics in a Brazilian region

Joyce Marinho de Souza, Rogério Giuffrida, Ana Paula Marques Ramos, Glilciane Morceli, Camila H. Coelho, Marcus Vinícius Pimenta Rodrigues

PLOS Neglected Tropical Diseases: published February 21, 2019 | https://doi.org/10.1371/journal.pntd.0007122

Long term outcomes and prognostics of visceral leishmaniasis in HIV infected patients with use of pentamidine as secondary prophylaxis based on CD4 level: a prospective cohort study in Ethiopia

Ermias Diro, Tansy Edwards, Koert Ritmeijer, Helina Fikre, Charles Abongomera, Aderajew Kibret, Clélia Bardonneau, Peninah Soipei, Brian Mutinda, Raymond Omollo, Johan van Griensven, Eduard E. Zijlstra, Monique Wasunna, Fabiana Alves, Jorge Alvar, Asrat Hailu, Neal Alexander, Séverine Blesson

PLOS Neglected Tropical Diseases: published February 21, 2019 | https://doi.org/10.1371/journal.pntd.0007132

Extracellular vesicles of Trypanosoma cruzi tissue-culture cell-derived trypomastigotes: Induction of physiological changes in non-parasitized culture cells

Lissette Retana Moreira, Fernando Rodríguez Serrano, Antonio Osuna

PLOS Neglected Tropical Diseases: published February 21, 2019 | https://doi.org/10.1371/journal.pntd.0007163

Implementation of a practical and effective pilot intervention against transmission of Taenia solium by pigs in the Banke district of Nepal

Ishab Poudel, Keshav Sah, Suyog Subedi, Dinesh Kumar Singh, Peetambar Kushwaha, Angela Colston, Charles G. Gauci, Meritxell Donadeu, Marshall W. Lightowlers

PLOS Neglected Tropical Diseases: published February 25, 2019 | https://doi.org/10.1371/journal.pntd.0006838

A single test approach for accurate and sensitive detection and taxonomic characterization of Trypanosomes by comprehensive analysis of internal transcribed spacer 1 amplicons

Alex Kiarie Gaithuma, Junya Yamagishi, Axel Martinelli, Kyoko Hayashida, Naoko Kawai, Megasari Marsela, Chihiro Sugimoto

PLOS Neglected Tropical Diseases: published February 25, 2019 | https://doi.org/10.1371/journal.pntd.0006842

Cutaneous leishmaniasis and co-morbid major depressive disorder: A systematic review with burden estimates

Freddie Bailey, Karina Mondragon-Shem, Lee Rafuse Haines, Amina Olabi, Ahmed Alorfi, José Antonio Ruiz-Postigo, Jorge Alvar, Peter Hotez, Emily R. Adams, Iván D. Vélez, Waleed Al-Salem, Julian Eaton, Álvaro Acosta-Serrano, David H. Molyneux

PLOS Neglected Tropical Diseases: published February 25, 2019 | https://doi.org/10.1371/journal.pntd.0007092

Epidemiological situation of yaws in the Americas: A systematic review in the context of a regional elimination goal

Ana Clara Zoni, Martha Idalí Saboyá-Díaz, Luis Gerardo Castellanos, Rubén Santiago Nicholls, Vendula Blaya-Novakova

PLOS Neglected Tropical Diseases: published February 25, 2019 | https://doi.org/10.1371/journal.pntd.0007125

The role of TLR9 on Leishmania amazonensis infection and its influence on intranasal LaAg vaccine efficacy

Juliana Elena Silveira Pratti, Alessandra Marcia da Fonseca Martins, Juliana Paiva da Silva, Tadeu Diniz Ramos, Joyce Carvalho Pereira, Luan Firmino-Cruz, Diogo Oliveira-Maciel, Thiago Soares de Souza Vieira, Leandra Linhares Lacerda, Andre Macedo Vale, Celio G. Freire-de-Lima, Daniel C. Oliveira Gomes, Elvira M. Saraiva, Bartira Rossi-Bergmann, Herbert Leonel de Matos Guedes

PLOS Neglected Tropical Diseases: published February 25, 2019 | https://doi.org/10.1371/journal.pntd.0007146

Hospitalisations and outpatient visits for undifferentiated fever attributable to scrub typhus in rural South India: Retrospective cohort and nested case-control study

Carol S. Devamani, John A. J. Prakash, Neal Alexander, Motoi Suzuki, Wolf-Peter Schmidt

PLOS Neglected Tropical Diseases: published February 25, 2019 | https://doi.org/10.1371/journal.pntd.0007160

In vitro activity and mode of action of phenolic compounds on Leishmania donovani

Christine Achiaa Antwi, Cynthia Mmalebna Amisigo, Jonathan Partt Adjimani, Theresa Manful Gwira

PLOS Neglected Tropical Diseases: published February 25, 2019 | https://doi.org/10.1371/journal.pntd.0007206

Caprine humoral response to Burkholderia pseudomallei antigens during acute melioidosis from aerosol exposure

Jinhee Yi, Mukoma F. Simpanya, Erik W. Settles, Austin B. Shannon, Karen Hernandez, Lauren Pristo, Mitchell E. Keener, Heidie Hornstra, Joseph D. Busch, Carl Soffler, Paul J. Brett, Bart J. Currie, Richard A. Bowen, Apichai Tuanyok, Paul Keim

PLOS Neglected Tropical Diseases: published February 27, 2019 | https://doi.org/10.1371/journal.pntd.0006851

Association of rodent-borne Leptospira spp. with urban environments in Malaysian Borneo

Kim R. Blasdell, Serge Morand, David Perera, Cadhla Firth

PLOS Neglected Tropical Diseases: published February 27, 2019 | https://doi.org/10.1371/journal.pntd.0007141

Ebola virus disease-related stigma among survivors declined in Liberia over an 18-month, post-outbreak period: An observational cohort study

J. Daniel Kelly, Sheri D. Weiser, Barthalomew Wilson, Joseph B. Cooper, Meekie Glayweon, Michael C. Sneller, Clara Drew, Wayne T. Steward, Cavan Reilly, Kumblytee Johnson, Mosoka P. Fallah

PLOS Neglected Tropical Diseases: published February 27, 2019 | https://doi.org/10.1371/journal.pntd.0007185

The importance of extracellular vesicle purification for downstream analysis: A comparison of differential centrifugation and size exclusion chromatography for helminth pathogens

Chelsea N. Davis, Helen Phillips, John J. Tomes, Martin T. Swain, Toby J. Wilkinson, Peter M. Brophy, Russell M. Morphew

PLOS Neglected Tropical Diseases: published February 27, 2019 | https://doi.org/10.1371/journal.pntd.0007191

Anti-leishmanial activity of Brevinin 2R and its Lauric acid conjugate type against L. major: In vitro mechanism of actions and in vivo treatment potentials

Farnaz Zahedifard, Hyeryon Lee, Joo Hwan No, Mona Salimi, Negar Seyed, Ahmad Asoodeh, Sima Rafati

PLOS Neglected Tropical Diseases: published February 27, 2019 | https://doi.org/10.1371/journal.pntd.0007217

Discovery of ABBV-4083, a novel analog of Tylosin A that has potent anti-Wolbachia and anti-filarial activity

Thomas W. von Geldern, Howard E. Morton, Rick F. Clark, Brian S. Brown, Kelly L. Johnston, Louise Ford, Sabine Specht, Robert A. Carr, Deanne F. Stolarik, Junli Ma, Matthew J. Rieser, Dominique Struever, Stefan J. Frohberger, Marianne Koschel, Alexandra Ehrens, Joseph D. Turner, Marc P. Hübner, Achim Hoerauf, Mark J. Taylor, Stephen A. Ward, Kennan Marsh, Dale J. Kempf

PLOS Neglected Tropical Diseases: published February 28, 2019 | https://doi.org/10.1371/journal.pntd.0007159

A multi-country study of the economic burden of dengue fever based on patient-specific field surveys in Burkina Faso, Kenya, and Cambodia

Jung-Seok Lee, Vittal Mogasale, Jacqueline K. Lim, Sowath Ly, Kang Sung Lee, Sopheak Sorn, Esther Andia, Mabel Carabali, Suk Namkung, Sl-Ki Lim, Valéry Ridde, Sammy M. Njenga, Seydou Yaro, In-Kyu Yoon

PLOS Neglected Tropical Diseases: published February 28, 2019 | https://doi.org/10.1371/journal.pntd.0007164

Parasitic infections during pregnancy need not affect infant antibody responses to early vaccination against Streptococcus pneumoniae, diphtheria, or Haemophilus influenzae type B

Noah D. McKittrick, Indu J. Malhotra, David M. Vu, Derek B. Boothroyd, Justin Lee, Amy R. Krystosik, Francis M. Mutuku, Charles H. King, A. Desirée LaBeaud

PLOS Neglected Tropical Diseases: published February 28, 2019 | https://doi.org/10.1371/journal.pntd.0007172

Efficacy of novel indoor residual spraying methods targeting pyrethroid-resistant Aedes aegypti within experimental houses

Mike W. Dunbar, Fabian Correa-Morales, Felipe Dzul-Manzanilla, Anuar Medina-Barreiro, Wilbert Bibiano-Marín, Evaristo Morales-Ríos, José Vadillo-Sánchez, Beatriz López-Monroy, Scott A. Ritchie, Audrey Lenhart, Pablo Manrique-Saide, Gonzalo M. Vazquez-Prokopec

PLOS Neglected Tropical Diseases: published February 28, 2019 | https://doi.org/10.1371/journal.pntd.0007203

Fast diagnosis of sporotrichosis caused by Sporothrix globosa, Sporothrix schenckii, and Sporothrix brasiliensis based on multiplex real-time PCR

Mingrui Zhang, Fuqiu Li, Ruoyu Li, Jie Gong, Fei Zhao

PLOS Neglected Tropical Diseases: published February 28, 2019 | https://doi.org/10.1371/journal.pntd.0007219

Corrections

Correction: Age trends in asymptomatic and symptomatic Leishmania donovani infection in the Indian subcontinent: A review and analysis of data from diagnostic and epidemiological studies

The PLOS Neglected Tropical Diseases Staff

PLOS Neglected Tropical Diseases: published February 26, 2019 | https://doi.org/10.1371/journal.pntd.0007150

Correction: Trypanosoma cruzi-specific IFN-γ-producing cells in chronic Chagas disease associate with a functional IL-7/IL-7R axis

María A. Natale, Gonzalo Cesar, Maria G. Alvarez, Melisa D. Castro Eiro, Bruno Lococo, Graciela Bertocchi, María C. Albareda, Susana A. Laucella

PLOS Neglected Tropical Diseases: published February 26, 2019 | https://doi.org/10.1371/journal.pntd.0007168

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