January 2019

Trained ophthalmologists conducted trachoma rapid assessment among children aged 6 to 7 in suspected trachoma endemic areas of China. Primary school students at first grade in Dingyuan county of Anhui province were examined. Ophthalmologists were equipped with loupes (×2.5 magnification) and torches to examine the everted upper eyelid whether active trachoma is present. Zhao, et al. (2019)

Image Credit: National Institute of Hospital Administration, China

Viewpoints

Assessing the risk of autochthonous yellow fever transmission in Lazio, central Italy

Mattia Manica, Giorgio Guzzetta, Federico Filipponi, Angelo Solimini, Beniamino Caputo, Alessandra della Torre, Roberto Rosà, Stefano Merler

PLOS Neglected Tropical Diseases: published January 10, 2019 | https://doi.org/10.1371/journal.pntd.0006970

Ghana: Accelerating neglected tropical disease control in a setting of economic development

Peter J. Hotez, Nana-Kwadwo Biritwum, Alan Fenwick, David H. Molyneux, Jeffrey D. Sachs

PLOS Neglected Tropical Diseases: published January 17, 2019 | https://doi.org/10.1371/journal.pntd.0007005

A therapeutic preconceptional vaccine against Chagas disease: A novel indication that could reduce congenital transmission and accelerate vaccine development

Eric Dumonteil, Claudia Herrera, Pierre Buekens

PLOS Neglected Tropical Diseases: published January 31, 2019 | https://doi.org/10.1371/journal.pntd.0006985

Policy Platform

China’s shifting neglected parasitic infections in an era of economic reform, urbanization, disease control, and the Belt and Road Initiative

Lei Wang, Yang Zou, Xinping Zhu, Maria Elena Bottazzi, Peter J. Hotez, Bin Zhan

PLOS Neglected Tropical Diseases: published January 24, 2019 | https://doi.org/10.1371/journal.pntd.0006946

Integrated delivery of school health interventions through the school platform: Investing for the future

Laura J. Appleby, Gemechu Tadesse, Yonas Wuletawu, Nigussie G. Dejene, Jack E. T. Grimes, Michael D. French, Askale Teklu, Berhanu Moreda, Nebiyu Negussu, Biruck Kebede, Elodie Yard, Iain Gardiner, Lesley J. Drake

PLOS Neglected Tropical Diseases: published January 31, 2019 | https://doi.org/10.1371/journal.pntd.0006449

Historical Profiles and Perspectives

Flubendazole as a macrofilaricide: History and background

Timothy G. Geary, Charles D. Mackenzie, Steven A. Silber

PLOS Neglected Tropical Diseases: published January 16, 2019 | https://doi.org/10.1371/journal.pntd.0006436

Reviews

Alternative strategies for mosquito-borne arbovirus control

Nicole L. Achee, John P. Grieco, Hassan Vatandoost, Gonçalo Seixas, Joao Pinto, Lee Ching-NG, Ademir J. Martins, Waraporn Juntarajumnong, Vincent Corbel, Clement Gouagna, Jean-Philippe David, James G. Logan, James Orsborne, Eric Marois, Gregor J. Devine, John Vontas

PLOS Neglected Tropical Diseases: published January 3, 2019 | https://doi.org/10.1371/journal.pntd.0006822

Chikungunya as a paradigm for emerging viral diseases: Evaluating disease impact and hurdles to vaccine development

Giovanni Rezza, Scott C. Weaver

PLOS Neglected Tropical Diseases: published January 17, 2019 | https://doi.org/10.1371/journal.pntd.0006919

Research Articles

Topical treatment with gallium maltolate reduces Treponema pallidum subsp. pertenue burden in primary experimental lesions in a rabbit model of yaws

Lorenzo Giacani, Lawrence R. Bernstein, Austin M. Haynes, B. Charmie Godornes, Giulia Ciccarese, Francesco Drago, Aurora Parodi, Sefora Valdevit, Luca Anselmi, Carlo Francesco Tomasini, Arthur M. Baca

PLOS Neglected Tropical Diseases: published January 2, 2019 | https://doi.org/10.1371/journal.pntd.0007076

Elimination within reach: A cross-sectional study highlighting the factors that contribute to persistent lymphatic filariasis in eight communities in rural Ghana

Corrado Minetti, Edward J. Tettevi, Frank Mechan, Joaquín M. Prada, Bright Idun, Nana-Kwadwo Biritwum, Mike Yaw Osei-Atweneboana, Lisa J. Reimer

PLOS Neglected Tropical Diseases: published January 4, 2019 | https://doi.org/10.1371/journal.pntd.0006994

Colonization factors among enterotoxigenic Escherichia coli isolates from children with moderate-to-severe diarrhea and from matched controls in the Global Enteric Multicenter Study (GEMS)

Roberto M. Vidal, Khitam Muhsen, Sharon M. Tennant, Ann-Mari Svennerholm, Samba O. Sow, Dipika Sur, Anita K. M. Zaidi, Abu S. G. Faruque, Debasish Saha, Richard Adegbola, M. Jahangir Hossain, Pedro L. Alonso, Robert F. Breiman, Quique Bassat, Boubou Tamboura, Doh Sanogo, Uma Onwuchekwa, Byomkesh Manna, Thandavarayan Ramamurthy, Suman Kanungo, Shahnawaz Ahmed, Shahida Qureshi, Farheen Quadri, Anowar Hossain, Sumon K. Das, Martin Antonio, Inacio Mandomando, Tacilta Nhampossa, Sozinho Acácio, Richard Omore, John B. Ochieng, Joseph O. Oundo, Eric D. Mintz, Ciara E. O’Reilly, Lynette Y. Berkeley, Sofie Livio, Sandra Panchalingam, Dilruba Nasrin, Tamer H. Farag, Yukun Wu, Halvor Sommerfelt, Roy M. Robins-Browne, Felipe Del Canto, Tracy H. Hazen, David A. Rasko, Karen L. Kotloff, James P. Nataro, Myron M. Levine

PLOS Neglected Tropical Diseases: published January 4, 2019 | https://doi.org/10.1371/journal.pntd.0007037

Extracellular vesicles from Echinococcus granulosus larval stage: Isolation, characterization and uptake by dendritic cells

María Celeste Nicolao, Christian Rodriguez Rodrigues, Andrea C. Cumino

PLOS Neglected Tropical Diseases: published January 7, 2019 | https://doi.org/10.1371/journal.pntd.0007032

Comparison of Mycobacterium ulcerans (Buruli ulcer) and Leptospira sp. (Leptospirosis) dynamics in urban and rural settings

Marine Combe, Rodolphe Elie Gozlan, Soushieta Jagadesh, Camilla Jensen Velvin, Rolland Ruffine, Magalie Pierre Demar, Pierre Couppié, Felix Djossou, Mathieu Nacher, Loïc Epelboin

PLOS Neglected Tropical Diseases: published January 7, 2019 | https://doi.org/10.1371/journal.pntd.0007074

Psychological burden and resilience factors in patients with Alveolar Echinococcosis – A cross-sectional study

Christoph Nikendei, Anja Greinacher, Anastasiya Berkunova, Thomas Junghanss, Marija Stojkovic

PLOS Neglected Tropical Diseases: published January 7, 2019 | https://doi.org/10.1371/journal.pntd.0007082

Matching the genetics of released and local Aedes aegypti populations is critical to assure Wolbachia invasion

Gabriela de Azambuja Garcia, Gabriel Sylvestre, Raquel Aguiar, Guilherme Borges da Costa, Ademir Jesus Martins, José Bento Pereira Lima, Martha T. Petersen, Ricardo Lourenço-de-Oliveira, Marion F. Shadbolt, Gordana Rašić, Ary A. Hoffmann, Daniel A. M. Villela, Fernando B. S. Dias, Yi Dong, Scott L. O’Neill, Luciano A. Moreira, Rafael Maciel-de-Freitas

PLOS Neglected Tropical Diseases: published January 8, 2019 | https://doi.org/10.1371/journal.pntd.0007023

Emergence of Madariaga virus as a cause of acute febrile illness in children, Haiti, 2015-2016

John A. Lednicky, Sarah K. White, Carla N. Mavian, Maha A. El Badry, Taina Telisma, Marco Salemi, Bernard A. OKech, V. Madsen Beau De Rochars, J. Glenn Morris Jr.

PLOS Neglected Tropical Diseases: published January 10, 2019 | https://doi.org/10.1371/journal.pntd.0006972

Economic burden of dengue in Indonesia

Mardiati Nadjib, Ery Setiawan, Septiara Putri, Joshua Nealon, Sophie Beucher, Sri Rezeki Hadinegoro, Vetty Yulianty Permanasari, Kurnia Sari, Tri Yunis Miko Wahyono, Erna Kristin, Dewa Nyoman Wirawan, Hasbullah Thabrany

PLOS Neglected Tropical Diseases: published January 10, 2019 | https://doi.org/10.1371/journal.pntd.0007038

Antagonistic effects of Plasmodium-helminth co-infections on malaria pathology in different population groups in Côte d’Ivoire

Eveline Hürlimann, Clarisse A. Houngbedji, Richard B. Yapi, Prisca B. N’Dri, Kigbafori D. Silué, Mamadou Ouattara, Jürg Utzinger, Eliézer K. N’Goran, Giovanna Raso

PLOS Neglected Tropical Diseases: published January 10, 2019 | https://doi.org/10.1371/journal.pntd.0007086

Improved DNA extraction technique from clot for the diagnosis of Chagas disease

Holger Mayta, Yomara K. Romero, Alejandra Pando, Manuela Verastegui, Freddy Tinajeros, Ricardo Bozo, Josephine Henderson-Frost, Rony Colanzi, Jorge Flores, Richard Lerner, Caryn Bern, Robert H. Gilman, for the Chagas Working Group in Perú and Bolivia

PLOS Neglected Tropical Diseases: published January 11, 2019 | https://doi.org/10.1371/journal.pntd.0007024

DNA plasmid coding for Phlebotomus sergenti salivary protein PsSP9, a member of the SP15 family of proteins, protects against Leishmania tropica

Elham Gholami, Fabiano Oliveira, Tahereh Taheri, Negar Seyed, Safoora Gharibzadeh, Nasim Gholami, Amir Mizbani, Fatemeh Zali, Sima Habibzadeh, Daniel Omid Bakhadj, Claudio Meneses, Kambiz Kamyab-Hesari, Alireza Sadeghipour, Yasaman Taslimi, Fatemeh khadir, Shaden Kamhawi, Mohammad Ali Mazlomi, Jesus G. Valenzuela, Sima Rafati

PLOS Neglected Tropical Diseases: published January 11, 2019 | https://doi.org/10.1371/journal.pntd.0007067

Community knowledge, attitude, and perceived stigma of leprosy amongst community members living in Dhanusha and Parsa districts of Southern Central Nepal

Rakesh Singh, Babita Singh, Sharika Mahato

PLOS Neglected Tropical Diseases: published January 11, 2019 | https://doi.org/10.1371/journal.pntd.0007075

Metagenomic profiling of ticks: Identification of novel rickettsial genomes and detection of tick-borne canine parvovirus

Anuradha Ravi, Suheir Ereqat, Amer Al-Jawabreh, Ziad Abdeen, Omar Abu Shamma, Holly Hall, Mark J. Pallen, Abedelmajeed Nasereddin

PLOS Neglected Tropical Diseases: published January 14, 2019 | https://doi.org/10.1371/journal.pntd.0006805

Follow-up study of high-dose praziquantel therapy for cerebral sparganosis

Peng Zhang, Yang Zou, Feng-Xia Yu, Zheng Wang, Han Lv, Xue-Huan Liu, He-Yu Ding, Ting-Ting Zhang, Peng-Fei Zhao, Hong-Xia Yin, Zheng-Han Yang, Zhen-Chang Wang

PLOS Neglected Tropical Diseases: published January 14, 2019 | https://doi.org/10.1371/journal.pntd.0007018

The reemergence of human rabies and emergence of an Indian subcontinent lineage in Tibet, China

Xiao-Yan Tao, Mu-Li Li, Qian Wang, Ciwang Baima, Mei Hong, Wei Li, Yong-Biao Wu, Yan-Rong Li, Yu-Min Zhao, Simon Rayner, Wu-Yang Zhu

PLOS Neglected Tropical Diseases: published January 14, 2019 | https://doi.org/10.1371/journal.pntd.0007036

Risk factors for hospitalization of patients with chikungunya virus infection at sentinel hospitals in Puerto Rico

Christopher H. Hsu, Fabiola Cruz-Lopez, Danulka Vargas Torres, Janice Perez-Padilla, Olga D. Lorenzi, Aidsa Rivera, J. Erin Staples, Esteban Lugo, Jorge Munoz-Jordan, Marc Fischer, Carlos Garcia Gubern, Brenda Rivera Garcia, Luisa Alvarado, Tyler M. Sharp

PLOS Neglected Tropical Diseases: published January 14, 2019 | https://doi.org/10.1371/journal.pntd.0007084

Utilization of proliferable extracellular amastigotes for transient gene expression, drug sensitivity assay, and CRISPR/Cas9-mediated gene knockout in Trypanosoma cruzi

Yuko Takagi, Yukie Akutsu, Motomichi Doi, Koji Furukawa

PLOS Neglected Tropical Diseases: published January 14, 2019 | https://doi.org/10.1371/journal.pntd.0007088

Macrofilaricidal efficacy of single and repeated oral and subcutaneous doses of flubendazole in Litomosoides sigmodontis infected jirds

Marc P. Hübner, Alexandra Ehrens, Marianne Koschel, Bettina Dubben, Franziska Lenz, Stefan J. Frohberger, Sabine Specht, Ludo Quirynen, Sophie Lachau-Durand, Fetene Tekle, Benny Baeten, Marc Engelen, Charles D. Mackenzie, Achim Hoerauf

PLOS Neglected Tropical Diseases: published January 16, 2019 | https://doi.org/10.1371/journal.pntd.0006320

Short-course, oral flubendazole does not mediate significant efficacy against Onchocerca adult male worms or Brugia microfilariae in murine infection models

Hanna T. Sjoberg, Nicolas Pionnier, Ghaith Aljayyoussi, Haelly M. Metuge, Abdel J. Njouendou, Valerine C. Chunda, Fanny F. Fombad, Dizzle B. Tayong, Narcisse V. T. Gandjui, Desmond N. Akumtoh, Patrick W. N. Chounna, Bertrand L. Ndzeshang, Sophie Lachaud, Fetene Tekle, Ludo Quirynen, Marc Engelen, Benny Baeten, Andrew Steven, Stephen A. Ward, Mark J. Taylor, Samuel Wanji, Joseph D. Turner

PLOS Neglected Tropical Diseases: published January 16, 2019 | https://doi.org/10.1371/journal.pntd.0006356

Efficacy of subcutaneous doses and a new oral amorphous solid dispersion formulation of flubendazole on male jirds (Meriones unguiculatus) infected with the filarial nematode Brugia pahangi

Chelsea Fischer, Iosune Ibiricu Urriza, Christina A. Bulman, KC Lim, Jiri Gut, Sophie Lachau-Durand, Marc Engelen, Ludo Quirynen, Fetene Tekle, Benny Baeten, Brenda Beerntsen, Sara Lustigman, Judy Sakanari

PLOS Neglected Tropical Diseases: published January 16, 2019 | https://doi.org/10.1371/journal.pntd.0006787

Preclinical toxicity and pharmacokinetics of a new orally bioavailable flubendazole formulation and the impact for clinical trials and risk/benefit to patients

Sophie Lachau-Durand, Lieve Lammens, Bas-jan van der Leede, Jacky Van Gompel, Graham Bailey, Marc Engelen, Ann Lampo

PLOS Neglected Tropical Diseases: published January 16, 2019 | https://doi.org/10.1371/journal.pntd.0007026

Association study between CCR2-CCR5 genes polymorphisms and chronic Chagas heart disease in Wichi and in admixed populations from Argentina

Natalia Anahí Juiz, Elkyn Estupiñán, Daniel Hernández, Alejandra Garcilazo, Raúl Chadi, Gisela Morales Sanfurgo, Alejandro Gabriel Schijman, Silvia Andrea Longhi, Clara Isabel González

PLOS Neglected Tropical Diseases: published January 16, 2019 | https://doi.org/10.1371/journal.pntd.0007033

A randomized trial of AmBisome monotherapy and AmBisome and miltefosine combination to treat visceral leishmaniasis in HIV co-infected patients in Ethiopia

Ermias Diro, Severine Blesson, Tansy Edwards, Koert Ritmeijer, Helina Fikre, Henok Admassu, Aderajew Kibret, Sally J. Ellis, Clelia Bardonneau, Eduard E. Zijlstra, Peninah Soipei, Brian Mutinda, Raymond Omollo, Robert Kimutai, Gabriel Omwalo, Monique Wasunna, Fentahun Tadesse, Fabiana Alves, Nathalie Strub-Wourgaft, Asrat Hailu, Neal Alexander, Jorge Alvar

PLOS Neglected Tropical Diseases: published January 17, 2019 | https://doi.org/10.1371/journal.pntd.0006988

Epidemiology of Strongyloides stercoralis infection in Bolivian patients at high risk of complications

Laurent Gétaz, Rosario Castro, Pablo Zamora, Marcelo Kramer, Nestor Gareca, Maria del Carmen Torrico-Espinoza, José Macias, Susana Lisarazu-Velásquez, Gloria Rodriguez, Carola Valencia-Rivero, Thomas Perneger, François Chappuis

PLOS Neglected Tropical Diseases: published January 17, 2019 | https://doi.org/10.1371/journal.pntd.0007028

A secreted schistosome cathepsin B1 cysteine protease and acute schistosome infection induce a transient T helper 17 response

Kateryna Soloviova, Ellen C. Fox, John P. Dalton, Conor R. Caffrey, Stephen J. Davies

PLOS Neglected Tropical Diseases: published January 17, 2019 | https://doi.org/10.1371/journal.pntd.0007070

High-accuracy detection of malaria vector larval habitats using drone-based multispectral imagery

Gabriel Carrasco-Escobar, Edgar Manrique, Jorge Ruiz-Cabrejos, Marlon Saavedra, Freddy Alava, Sara Bickersmith, Catharine Prussing, Joseph M. Vinetz, Jan E. Conn, Marta Moreno, Dionicia Gamboa

PLOS Neglected Tropical Diseases: published January 17, 2019 | https://doi.org/10.1371/journal.pntd.0007105

Development of a preliminary in vitro drug screening assay based on a newly established culturing system for pre-adult fifth-stage Onchocerca volvulus worms

Denis Voronin, Nancy Tricoche, Shabnam Jawahar, Michael Shlossman, Christina A. Bulman, Chelsea Fischer, Michael T. Suderman, Judy A. Sakanari, Sara Lustigman

PLOS Neglected Tropical Diseases: published January 17, 2019 | https://doi.org/10.1371/journal.pntd.0007108

The impact of imperfect screening tools on measuring the prevalence of epilepsy and headaches in Burkina Faso

Ida Sahlu, Cici Bauer, Rasmané Ganaba, Pierre-Marie Preux, Linda D. Cowan, Pierre Dorny, Athanase Millogo, Hélène Carabin

PLOS Neglected Tropical Diseases: published January 17, 2019 | https://doi.org/10.1371/journal.pntd.0007109

Naja annulifera Snake: New insights into the venom components and pathogenesis of envenomation

Felipe Silva-de-França, Isadora Maria Villas-Boas, Solange Maria de Toledo Serrano, Bruno Cogliati, Sonia Aparecida de Andrade Chudzinski, Priscila Hess Lopes, Eduardo Shigueo Kitano, Cinthya Kimori Okamoto, Denise V. Tambourgi

PLOS Neglected Tropical Diseases: published January 18, 2019 | https://doi.org/10.1371/journal.pntd.0007017

Surface molecules of extracellular vesicles secreted by the helminth pathogen Fasciola hepatica direct their internalisation by host cells

Eduardo de la Torre-Escudero, Jared Q. Gerlach, Adam P. S. Bennett, Krystyna Cwiklinski, Heather L. Jewhurst, Kathryn M. Huson, Lokesh Joshi, Michelle Kilcoyne, Sandra O’Neill, John P. Dalton, Mark W. Robinson

PLOS Neglected Tropical Diseases: published January 18, 2019 | https://doi.org/10.1371/journal.pntd.0007087

A systematic review and meta-analysis of the prevalence of osteoarticular brucellosis

Shakirat A. Adetunji, Gilbert Ramirez, Margaret J. Foster, Angela M. Arenas-Gamboa

PLOS Neglected Tropical Diseases: published January 18, 2019 | https://doi.org/10.1371/journal.pntd.0007112

A Biomphalaria glabrata peptide that stimulates significant behaviour modifications in aquatic free-living Schistosoma mansoni miracidia

Tianfang Wang, Russell C. Wyeth, Di Liang, Utpal Bose, Guoying Ni, Donald P. McManus, Scott F. Cummins

PLOS Neglected Tropical Diseases: published January 22, 2019 | https://doi.org/10.1371/journal.pntd.0006948

Synthetic peptides as a novel approach for detecting antibodies against sand fly saliva

Michal Sima, Blanka Ferencova, Tapan Bhattacharyya, Michael A. Miles, Sergey V. Litvinov, Asrat Hailu, Gad Baneth, Petr Volf

PLOS Neglected Tropical Diseases: published January 24, 2019 | https://doi.org/10.1371/journal.pntd.0007078

Estimating the association between being seropositive for cysticercosis and the prevalence of epilepsy and severe chronic headaches in 60 villages of rural Burkina Faso

Ida Sahlu, Hélène Carabin, Rasmané Ganaba, Pierre-Marie Preux, Assana Kone Cissé, Zekiba Tarnagda, Sarah Gabriël, Veronique Dermauw, Pierre Dorny, Cici Bauer, Athanase Millogo

PLOS Neglected Tropical Diseases: published January 24, 2019 | https://doi.org/10.1371/journal.pntd.0007101

3D images as a field grader training tool for trachomatous trichiasis: A diagnostic accuracy study in Ethiopia

Jeremy J. Hoffman, Esmael Habtamu, Hillary Rono, Zerihun Tadesse, Tariku Wondie, Temesgen Minas, Bizuayehu Gashaw, E. Kelly Callahan, David MacLeod, Matthew J. Burton

PLOS Neglected Tropical Diseases: published January 24, 2019 | https://doi.org/10.1371/journal.pntd.0007104

Discovery of Leptospira spp. seroreactive peptides using ORFeome phage display

Siti Roszilawati Ramli, Gustavo M. S. G. Moreira, Jonas Zantow, Marga G. A. Goris, Van Kinh Nguyen, Natalia Novoselova, Frank Pessler, Michael Hust

PLOS Neglected Tropical Diseases: published January 24, 2019 | https://doi.org/10.1371/journal.pntd.0007131

Does prior dengue virus exposure worsen clinical outcomes of Zika virus infection? A systematic review, pooled analysis and lessons learned

Jennifer Masel, Michael K. McCracken, Todd Gleeson, Brian Morrison, George Rutherford, Allison Imrie, Richard G. Jarman, Michael Koren, Simon Pollett

PLOS Neglected Tropical Diseases: published January 25, 2019 | https://doi.org/10.1371/journal.pntd.0007060

Knowledge, attitudes and practices (KAP) towards rabies and free-roaming dogs (FRD) in Shirsuphal village in western India: A community based cross-sectional study

Harish Kumar Tiwari, Mark O’Dea, Ian Duncan Robertson, Abi Tamim Vanak

PLOS Neglected Tropical Diseases: published January 25, 2019 | https://doi.org/10.1371/journal.pntd.0007120

A novel cell-free method to culture Schistosoma mansoni from cercariae to juvenile worm stages for in vitro drug testing

Sören Frahm, Anisuzzaman Anisuzzaman, Ulrich Fabien Prodjinotho, Nermina Vejzagić, Admar Verschoor, Clarissa Prazeres da Costa

PLOS Neglected Tropical Diseases: published January 28, 2019 | https://doi.org/10.1371/journal.pntd.0006590

Genetic variation and phylogeography of the Triatoma dimidiata complex evidence a potential center of origin and recent divergence of haplogroups having differential Trypanosoma cruzi and DTU infections

Angélica Pech-May, Carlos Jesús Mazariegos-Hidalgo, Amaia Izeta-Alberdi, Sury Antonio López-Cancino, Ezequiel Tun-Ku, Keynes De la Cruz-Félix, Carlos N. Ibarra-Cerdeña, Raúl E. González Ittig, Janine M. Ramsey

PLOS Neglected Tropical Diseases: published January 28, 2019 | https://doi.org/10.1371/journal.pntd.0007044

Community based cross sectional study of podoconiosis and associated factors in Dano district, Central Ethiopia

Feven Dejene, Hailu Merga, Henok Asefa

PLOS Neglected Tropical Diseases: published January 28, 2019 | https://doi.org/10.1371/journal.pntd.0007050

Population genetic structure and geographical variation in Neotricula aperta (Gastropoda: Pomatiopsidae), the snail intermediate host of Schistosoma mekongi (Digenea: Schistosomatidae)

Stephen W. Attwood, Liang Liu, Guan-Nan Huo

PLOS Neglected Tropical Diseases: published January 28, 2019 | https://doi.org/10.1371/journal.pntd.0007061

Differential immunoglobulin and complement levels in leprosy prior to development of reversal reaction and erythema nodosum leprosum

Francianne M. Amorim, Maurício L. Nobre, Larissa S. Nascimento, Alesson M. Miranda, Glória R. G. Monteiro, Francisco P. Freire-Neto, Maria do Carmo Palmeira Queiroz, José W. Queiroz, Malcolm S. Duthie, Marcos R. Costa, Steven G. Reed, Warren D. Johnson Jr., Kathryn M. Dupnik, Selma M. B. Jeronimo

PLOS Neglected Tropical Diseases: published January 28, 2019 | https://doi.org/10.1371/journal.pntd.0007089

Triple oral beta-lactam containing therapy for Buruli ulcer treatment shortening

María Pilar Arenaz-Callao, Rubén González del Río, Ainhoa Lucía Quintana, Charles J. Thompson, Alfonso Mendoza-Losana, Santiago Ramón-García

PLOS Neglected Tropical Diseases: published January 28, 2019 | https://doi.org/10.1371/journal.pntd.0007126

Community-level chlamydial serology for assessing trachoma elimination in trachoma-endemic Niger

Jessica S. Kim, Catherine E. Oldenburg, Gretchen Cooley, Abdou Amza, Boubacar Kadri, Baido Nassirou, Sun Yu Cotter, Nicole E. Stoller, Sheila K. West, Robin L. Bailey, Jeremy D. Keenan, Bruce D. Gaynor, Travis C. Porco, Thomas M. Lietman, Diana L. Martin

PLOS Neglected Tropical Diseases: published January 28, 2019 | https://doi.org/10.1371/journal.pntd.0007127

Assessment of trachoma in suspected endemic areas within 16 provinces in mainland China

Jialiang Zhao, Silvio Paolo Mariotti, Serge Resnikoff, Yuqin Wang, Shicheng Yu, Mingguang He, Yingchuan Fan, Haidong Zou, Wenfang Zhang, Yading Jia, Lihua Wang, Huaijin Guan, Xiao Xu, Leilei Zhan, Lei An, Quanfu Ye, Ningli Wang

PLOS Neglected Tropical Diseases: published January 28, 2019 | https://doi.org/10.1371/journal.pntd.0007130

Mechanisms underpinning the permanent muscle damage induced by snake venom metalloprotease

Harry F. Williams, Ben A. Mellows, Robert Mitchell, Peggy Sfyri, Harry J. Layfield, Maryam Salamah, Rajendran Vaiyapuri, Henry Collins-Hooper, Andrew B. Bicknell, Antonios Matsakas, Ketan Patel, Sakthivel Vaiyapuri

PLOS Neglected Tropical Diseases: published January 29, 2019 | https://doi.org/10.1371/journal.pntd.0007041

Knowledge, attitudes, and practices regarding rabies in Grenada

Lindonne Glasgow, Andre Worme, Emmanuel Keku, Martin Forde

PLOS Neglected Tropical Diseases: published January 29, 2019 | https://doi.org/10.1371/journal.pntd.0007079

Epidemiology of West Nile Virus in the Eastern Mediterranean region: A systematic review

Sana Eybpoosh, Mehdi Fazlalipour, Vahid Baniasadi, Mohammad Hassan Pouriayevali, Farzin Sadeghi, Abbas Ahmadi Vasmehjani, Mohammad Hadi Karbalaie Niya, Roger Hewson, Mostafa Salehi-Vaziri

PLOS Neglected Tropical Diseases: published January 29, 2019 | https://doi.org/10.1371/journal.pntd.0007081

Neglected tropical diseases in children: An assessment of gaps in research prioritization

Chris A. Rees, Peter J. Hotez, Michael C. Monuteaux, Michelle Niescierenko, Florence T. Bourgeois

PLOS Neglected Tropical Diseases: published January 29, 2019 | https://doi.org/10.1371/journal.pntd.0007111

Utility of rabies neutralizing antibody detection in cerebrospinal fluid and serum for ante-mortem diagnosis of human rabies

Tina Damodar, Reeta S. Mani, P. V. Prathyusha

PLOS Neglected Tropical Diseases: published January 29, 2019 | https://doi.org/10.1371/journal.pntd.0007128

Integrated seroprevalence-based assessment of Wuchereria bancrofti and Onchocerca volvulus in two lymphatic filariasis evaluation units of Mali with the SD Bioline Onchocerciasis/LF IgG4 Rapid Test

Housseini Dolo, Yaya Ibrahim Coulibaly, Benoit Dembele, Boubacar Guindo, Siaka Yamoussa Coulibaly, Ilo Dicko, Salif Seriba Doumbia, Massitan Dembele, Mamadou Oumar Traore, Seydou Goita, Mamadou Dolo, Lamine Soumaoro, Michel Emmanuel Coulibaly, Abdallah Amadou Diallo, Dansine Diarra, Yaobi Zhang, Robert Colebunders, Thomas B. Nutman

PLOS Neglected Tropical Diseases: published January 30, 2019 | https://doi.org/10.1371/journal.pntd.0007064

Yellow fever virus is susceptible to sofosbuvir both in vitro and in vivo

Caroline S. de Freitas, Luiza M. Higa, Carolina Q. Sacramento, André C. Ferreira, Patrícia A. Reis, Rodrigo Delvecchio, Fabio L. Monteiro, Giselle Barbosa-Lima, Harrison James Westgarth, Yasmine Rangel Vieira, Mayara Mattos, Natasha Rocha, Lucas Villas Bôas Hoelz, Rennan Papaleo Paes Leme, Mônica M. Bastos, Gisele Olinto L. Rodrigues, Carla Elizabeth M. Lopes, Celso Martins Queiroz-Junior, Cristiano X. Lima, Vivian V. Costa, Mauro M. Teixeira, Fernando A. Bozza, Patrícia T. Bozza, Nubia Boechat, Amilcar Tanuri, Thiago Moreno L. Souza

PLOS Neglected Tropical Diseases: published January 30, 2019 | https://doi.org/10.1371/journal.pntd.0007072

Food insecurity and self-reported cholera in Haitian households: An analysis of the 2012 Demographic and Health Survey

Aaron Richterman, Molly F. Franke, Georgery Constant, Gregory Jerome, Ralph Ternier, Louise C. Ivers

PLOS Neglected Tropical Diseases: published January 30, 2019 | https://doi.org/10.1371/journal.pntd.0007134

Bivalent oral cholera vaccination induces a memory B cell response to the V. cholerae O1-polysaccharide antigen in Haitian adults

Brie Falkard, Richelle C. Charles, Wilfredo R. Matias, Leslie M. Mayo-Smith, J. Gregory Jerome, Evan S. Offord, Peng Xu, Pavol Kováč, Edward T. Ryan, Firdausi Qadri, Molly F. Franke, Louise C. Ivers, Jason B. Harris

PLOS Neglected Tropical Diseases: published January 31, 2019 | https://doi.org/10.1371/journal.pntd.0007057

The long run impact of early childhood deworming on numeracy and literacy: Evidence from Uganda

Kevin Croke, Rifat Atun

PLOS Neglected Tropical Diseases: published January 31, 2019 | https://doi.org/10.1371/journal.pntd.0007085

Probabilistic logic analysis of the highly heterogeneous spatiotemporal HFRS incidence distribution in Heilongjiang province (China) during 2005-2013

Junyu He, George Christakos, Jiaping Wu, Piotr Jankowski, Andreas Langousis, Yong Wang, Wenwu Yin, Wenyi Zhang

PLOS Neglected Tropical Diseases: published January 31, 2019 | https://doi.org/10.1371/journal.pntd.0007091

Evaluation of direct costs associated with alveolar and cystic echinococcosis in Austria

Felix Lötsch, Christine M. Budke, Herbert Auer, Klaus Kaczirek, Fredrik Waneck, Heimo Lagler, Michael Ramharter

PLOS Neglected Tropical Diseases: published January 31, 2019 | https://doi.org/10.1371/journal.pntd.0007110

Field evaluation of a locally produced rapid diagnostic test for early detection of cholera in Bangladesh

Md. Taufiqul Islam, Ashraful Islam Khan, Md. Abu Sayeed, Jakia Amin, Kamrul Islam, Nur Alam, Nishat Sultana, Noor Jahan, Md. Mahbubur Rashid, Zahid Hasan Khan, Mazharul Islam Zion, Mokibul Hassan Afrad, Shah Alam Siddique, Farhana Khanam, Yasmin Ara Begum, Muhammad Shariful Islam, Firdausi Qadri

PLOS Neglected Tropical Diseases: published January 31, 2019 | https://doi.org/10.1371/journal.pntd.0007124

Growing evidence of Plasmodium vivax across malaria-endemic Africa

Katherine A. Twohig, Daniel A. Pfeffer, J. Kevin Baird, Ric N. Price, Peter A. Zimmerman, Simon I. Hay, Peter W. Gething, Katherine E. Battle, Rosalind E. Howes

PLOS Neglected Tropical Diseases: published January 31, 2019 | https://doi.org/10.1371/journal.pntd.0007140

Correction

Correction: The spectrum of neurological disease associated with Zika and chikungunya viruses in adults in Rio de Janeiro, Brazil: A case series

The PLOS Neglected Tropical Diseases Staff

PLOS Neglected Tropical Diseases: published January 31, 2019 | https://doi.org/10.1371/journal.pntd.0007166

Cover

Assessing the Active Trachoma in Anhui Province, China, May 2014

Viewpoints

Policy Platform

Historical Profiles and Perspectives

Reviews

Related Articles

Research Articles

Related Articles

Related Articles

Related Articles

Related Articles

Related Articles

Related Articles

Related Articles

Related Articles

Related Articles

Correction

Related Articles