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Table of Contents

January 2019

Trained ophthalmologists conducted trachoma rapid assessment among children aged 6 to 7 in suspected trachoma endemic areas of China. Primary school students at first grade in Dingyuan county of Anhui province were examined. Ophthalmologists were equipped with loupes (×2.5 magnification) and torches to examine the everted upper eyelid whether active trachoma is present. Zhao, et al. (2019)

Image Credit: National Institute of Hospital Administration, China

Viewpoints

Assessing the risk of autochthonous yellow fever transmission in Lazio, central Italy

Mattia Manica, Giorgio Guzzetta, Federico Filipponi, Angelo Solimini, Beniamino Caputo, Alessandra della Torre, Roberto Rosà, Stefano Merler

Ghana: Accelerating neglected tropical disease control in a setting of economic development

Peter J. Hotez, Nana-Kwadwo Biritwum, Alan Fenwick, David H. Molyneux, Jeffrey D. Sachs

Policy Platform

China’s shifting neglected parasitic infections in an era of economic reform, urbanization, disease control, and the Belt and Road Initiative

Lei Wang, Yang Zou, Xinping Zhu, Maria Elena Bottazzi, Peter J. Hotez, Bin Zhan

Integrated delivery of school health interventions through the school platform: Investing for the future

Laura J. Appleby, Gemechu Tadesse, Yonas Wuletawu, Nigussie G. Dejene, Jack E. T. Grimes, Michael D. French, Askale Teklu, Berhanu Moreda, Nebiyu Negussu, Biruck Kebede, Elodie Yard, Iain Gardiner, Lesley J. Drake

Historical Profiles and Perspectives

Flubendazole as a macrofilaricide: History and background

Timothy G. Geary, Charles D. Mackenzie, Steven A. Silber

Reviews

Alternative strategies for mosquito-borne arbovirus control

Nicole L. Achee, John P. Grieco, Hassan Vatandoost, Gonçalo Seixas, Joao Pinto, Lee Ching-NG, Ademir J. Martins, Waraporn Juntarajumnong, Vincent Corbel, Clement Gouagna, Jean-Philippe David, James G. Logan, James Orsborne, Eric Marois, Gregor J. Devine, John Vontas

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Research Articles

Topical treatment with gallium maltolate reduces Treponema pallidum subsp. pertenue burden in primary experimental lesions in a rabbit model of yaws

Lorenzo Giacani, Lawrence R. Bernstein, Austin M. Haynes, B. Charmie Godornes, Giulia Ciccarese, Francesco Drago, Aurora Parodi, Sefora Valdevit, Luca Anselmi, Carlo Francesco Tomasini, Arthur M. Baca

Elimination within reach: A cross-sectional study highlighting the factors that contribute to persistent lymphatic filariasis in eight communities in rural Ghana

Corrado Minetti, Edward J. Tettevi, Frank Mechan, Joaquín M. Prada, Bright Idun, Nana-Kwadwo Biritwum, Mike Yaw Osei-Atweneboana, Lisa J. Reimer

Colonization factors among enterotoxigenic Escherichia coli isolates from children with moderate-to-severe diarrhea and from matched controls in the Global Enteric Multicenter Study (GEMS)

Roberto M. Vidal, Khitam Muhsen, Sharon M. Tennant, Ann-Mari Svennerholm, Samba O. Sow, Dipika Sur, Anita K. M. Zaidi, Abu S. G. Faruque, Debasish Saha, Richard Adegbola, M. Jahangir Hossain, Pedro L. Alonso, Robert F. Breiman, Quique Bassat, Boubou Tamboura, Doh Sanogo, Uma Onwuchekwa, Byomkesh Manna, Thandavarayan Ramamurthy, Suman Kanungo, Shahnawaz Ahmed, Shahida Qureshi, Farheen Quadri, Anowar Hossain, Sumon K. Das, Martin Antonio, Inacio Mandomando, Tacilta Nhampossa, Sozinho Acácio, Richard Omore, John B. Ochieng, Joseph O. Oundo, Eric D. Mintz, Ciara E. O’Reilly, Lynette Y. Berkeley, Sofie Livio, Sandra Panchalingam, Dilruba Nasrin, Tamer H. Farag, Yukun Wu, Halvor Sommerfelt, Roy M. Robins-Browne, Felipe Del Canto, Tracy H. Hazen, David A. Rasko, Karen L. Kotloff, James P. Nataro, Myron M. Levine

Extracellular vesicles from Echinococcus granulosus larval stage: Isolation, characterization and uptake by dendritic cells

María Celeste Nicolao, Christian Rodriguez Rodrigues, Andrea C. Cumino

Comparison of Mycobacterium ulcerans (Buruli ulcer) and Leptospira sp. (Leptospirosis) dynamics in urban and rural settings

Marine Combe, Rodolphe Elie Gozlan, Soushieta Jagadesh, Camilla Jensen Velvin, Rolland Ruffine, Magalie Pierre Demar, Pierre Couppié, Felix Djossou, Mathieu Nacher, Loïc Epelboin

Psychological burden and resilience factors in patients with Alveolar Echinococcosis – A cross-sectional study

Christoph Nikendei, Anja Greinacher, Anastasiya Berkunova, Thomas Junghanss, Marija Stojkovic

Matching the genetics of released and local Aedes aegypti populations is critical to assure Wolbachia invasion

Gabriela de Azambuja Garcia, Gabriel Sylvestre, Raquel Aguiar, Guilherme Borges da Costa, Ademir Jesus Martins, José Bento Pereira Lima, Martha T. Petersen, Ricardo Lourenço-de-Oliveira, Marion F. Shadbolt, Gordana Rašić, Ary A. Hoffmann, Daniel A. M. Villela, Fernando B. S. Dias, Yi Dong, Scott L. O’Neill, Luciano A. Moreira, Rafael Maciel-de-Freitas

Emergence of Madariaga virus as a cause of acute febrile illness in children, Haiti, 2015-2016

John A. Lednicky, Sarah K. White, Carla N. Mavian, Maha A. El Badry, Taina Telisma, Marco Salemi, Bernard A. OKech, V. Madsen Beau De Rochars, J. Glenn Morris Jr.

Economic burden of dengue in Indonesia

Mardiati Nadjib, Ery Setiawan, Septiara Putri, Joshua Nealon, Sophie Beucher, Sri Rezeki Hadinegoro, Vetty Yulianty Permanasari, Kurnia Sari, Tri Yunis Miko Wahyono, Erna Kristin, Dewa Nyoman Wirawan, Hasbullah Thabrany

Antagonistic effects of Plasmodium-helminth co-infections on malaria pathology in different population groups in Côte d’Ivoire

Eveline Hürlimann, Clarisse A. Houngbedji, Richard B. Yapi, Prisca B. N’Dri, Kigbafori D. Silué, Mamadou Ouattara, Jürg Utzinger, Eliézer K. N’Goran, Giovanna Raso

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Anuradha Ravi, Suheir Ereqat, Amer Al-Jawabreh, Ziad Abdeen, Omar Abu Shamma, Holly Hall, Mark J. Pallen, Abedelmajeed Nasereddin

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The reemergence of human rabies and emergence of an Indian subcontinent lineage in Tibet, China

Xiao-Yan Tao, Mu-Li Li, Qian Wang, Ciwang Baima, Mei Hong, Wei Li, Yong-Biao Wu, Yan-Rong Li, Yu-Min Zhao, Simon Rayner, Wu-Yang Zhu

Risk factors for hospitalization of patients with chikungunya virus infection at sentinel hospitals in Puerto Rico

Christopher H. Hsu, Fabiola Cruz-Lopez, Danulka Vargas Torres, Janice Perez-Padilla, Olga D. Lorenzi, Aidsa Rivera, J. Erin Staples, Esteban Lugo, Jorge Munoz-Jordan, Marc Fischer, Carlos Garcia Gubern, Brenda Rivera Garcia, Luisa Alvarado, Tyler M. Sharp

Macrofilaricidal efficacy of single and repeated oral and subcutaneous doses of flubendazole in Litomosoides sigmodontis infected jirds

Marc P. Hübner, Alexandra Ehrens, Marianne Koschel, Bettina Dubben, Franziska Lenz, Stefan J. Frohberger, Sabine Specht, Ludo Quirynen, Sophie Lachau-Durand, Fetene Tekle, Benny Baeten, Marc Engelen, Charles D. Mackenzie, Achim Hoerauf

Short-course, oral flubendazole does not mediate significant efficacy against Onchocerca adult male worms or Brugia microfilariae in murine infection models

Hanna T. Sjoberg, Nicolas Pionnier, Ghaith Aljayyoussi, Haelly M. Metuge, Abdel J. Njouendou, Valerine C. Chunda, Fanny F. Fombad, Dizzle B. Tayong, Narcisse V. T. Gandjui, Desmond N. Akumtoh, Patrick W. N. Chounna, Bertrand L. Ndzeshang, Sophie Lachaud, Fetene Tekle, Ludo Quirynen, Marc Engelen, Benny Baeten, Andrew Steven, Stephen A. Ward, Mark J. Taylor, Samuel Wanji, Joseph D. Turner

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Efficacy of subcutaneous doses and a new oral amorphous solid dispersion formulation of flubendazole on male jirds (Meriones unguiculatus) infected with the filarial nematode Brugia pahangi

Chelsea Fischer, Iosune Ibiricu Urriza, Christina A. Bulman, KC Lim, Jiri Gut, Sophie Lachau-Durand, Marc Engelen, Ludo Quirynen, Fetene Tekle, Benny Baeten, Brenda Beerntsen, Sara Lustigman, Judy Sakanari

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Preclinical toxicity and pharmacokinetics of a new orally bioavailable flubendazole formulation and the impact for clinical trials and risk/benefit to patients

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Association study between CCR2-CCR5 genes polymorphisms and chronic Chagas heart disease in Wichi and in admixed populations from Argentina

Natalia Anahí Juiz, Elkyn Estupiñán, Daniel Hernández, Alejandra Garcilazo, Raúl Chadi, Gisela Morales Sanfurgo, Alejandro Gabriel Schijman, Silvia Andrea Longhi, Clara Isabel González

A randomized trial of AmBisome monotherapy and AmBisome and miltefosine combination to treat visceral leishmaniasis in HIV co-infected patients in Ethiopia

Ermias Diro, Severine Blesson, Tansy Edwards, Koert Ritmeijer, Helina Fikre, Henok Admassu, Aderajew Kibret, Sally J. Ellis, Clelia Bardonneau, Eduard E. Zijlstra, Peninah Soipei, Brian Mutinda, Raymond Omollo, Robert Kimutai, Gabriel Omwalo, Monique Wasunna, Fentahun Tadesse, Fabiana Alves, Nathalie Strub-Wourgaft, Asrat Hailu, Neal Alexander, Jorge Alvar

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Epidemiology of Strongyloides stercoralis infection in Bolivian patients at high risk of complications

Laurent Gétaz, Rosario Castro, Pablo Zamora, Marcelo Kramer, Nestor Gareca, Maria del Carmen Torrico-Espinoza, José Macias, Susana Lisarazu-Velásquez, Gloria Rodriguez, Carola Valencia-Rivero, Thomas Perneger, François Chappuis

A secreted schistosome cathepsin B1 cysteine protease and acute schistosome infection induce a transient T helper 17 response

Kateryna Soloviova, Ellen C. Fox, John P. Dalton, Conor R. Caffrey, Stephen J. Davies

High-accuracy detection of malaria vector larval habitats using drone-based multispectral imagery

Gabriel Carrasco-Escobar, Edgar Manrique, Jorge Ruiz-Cabrejos, Marlon Saavedra, Freddy Alava, Sara Bickersmith, Catharine Prussing, Joseph M. Vinetz, Jan E. Conn, Marta Moreno, Dionicia Gamboa

Development of a preliminary in vitro drug screening assay based on a newly established culturing system for pre-adult fifth-stage Onchocerca volvulus worms

Denis Voronin, Nancy Tricoche, Shabnam Jawahar, Michael Shlossman, Christina A. Bulman, Chelsea Fischer, Michael T. Suderman, Judy A. Sakanari, Sara Lustigman

Naja annulifera Snake: New insights into the venom components and pathogenesis of envenomation

Felipe Silva-de-França, Isadora Maria Villas-Boas, Solange Maria de Toledo Serrano, Bruno Cogliati, Sonia Aparecida de Andrade Chudzinski, Priscila Hess Lopes, Eduardo Shigueo Kitano, Cinthya Kimori Okamoto, Denise V. Tambourgi

Surface molecules of extracellular vesicles secreted by the helminth pathogen Fasciola hepatica direct their internalisation by host cells

Eduardo de la Torre-Escudero, Jared Q. Gerlach, Adam P. S. Bennett, Krystyna Cwiklinski, Heather L. Jewhurst, Kathryn M. Huson, Lokesh Joshi, Michelle Kilcoyne, Sandra O’Neill, John P. Dalton, Mark W. Robinson

A systematic review and meta-analysis of the prevalence of osteoarticular brucellosis

Shakirat A. Adetunji, Gilbert Ramirez, Margaret J. Foster, Angela M. Arenas-Gamboa

A Biomphalaria glabrata peptide that stimulates significant behaviour modifications in aquatic free-living Schistosoma mansoni miracidia

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Estimating the association between being seropositive for cysticercosis and the prevalence of epilepsy and severe chronic headaches in 60 villages of rural Burkina Faso

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