April 2015

Rabies is a notoriously underreported and neglected disease of low-income countries. This study aims to estimate the public health and economic burden of rabies circulating in domestic dog populations, globally and on a country-by-country basis, allowing an objective assessment of how much this preventable disease costs endemic countries. Hampson et al.

Image Credit: Katie Hampson

Editorial

Helminth Elimination in the Pursuit of Sustainable Development Goals: A "Worm Index" for Human Development

Peter J. Hotez, Jennifer R. Herricks

PLOS Neglected Tropical Diseases: published April 30, 2015 | https://doi.org/10.1371/journal.pntd.0003618

Viewpoints

The Missing Millions: A Threat to the Elimination of Leprosy

William Cairns Smith, Wim van Brakel, Tom Gillis, Paul Saunderson, Jan Hendrik Richardus

PLOS Neglected Tropical Diseases: published April 23, 2015 | https://doi.org/10.1371/journal.pntd.0003658

Extending the “Social”: Anthropological Contributions to the Study of Viral Haemorrhagic Fevers

Hannah Brown, Ann H. Kelly, Almudena Marí Sáez, Elisabeth Fichet-Calvet, Rashid Ansumana, Jesse Bonwitt, N’Faly Magassouba, Foday Sahr, Matthias Borchert

PLOS Neglected Tropical Diseases: published April 16, 2015 | https://doi.org/10.1371/journal.pntd.0003651

Long-lasting Insecticidal Nets to Prevent Visceral Leishmaniasis in the Indian Subcontinent; Methodological Lessons Learned from a Cluster Randomised Controlled Trial

Albert Picado, Bart Ostyn, Suman Rijal, Shyam Sundar, Shri Prakash Singh, François Chappuis, Murari Lal Das, Basudha Khanal, Kamlesh Gidwani, Epco Hasker, Jean Claude Dujardin, Veerle Vanlerberghe, Joris Menten, Marc Coosemans, Marleen Boelaert

PLOS Neglected Tropical Diseases: published April 9, 2015 | https://doi.org/10.1371/journal.pntd.0003597

Policy Platform

Opisthorchiasis: An Overlooked Danger

Ludmila M. Ogorodova, Olga S. Fedorova, Banchob Sripa, Viatcheslav A. Mordvinov, Aleksei V. Katokhin, Jennifer Keiser, Peter Odermatt, Paul J. Brindley, Oleg A. Mayboroda, Thirumalaisamy P. Velavan, Maxim B. Freidin, Alexey E. Sazonov, Irina V. Saltykova, Mariya Y Pakharukova, Yulia V. Kovshirina, Kostas Kaloulis, Olga Y. Krylova, Maria Yazdanbakhsh, the TOPIC Consortium

PLOS Neglected Tropical Diseases: published April 2, 2015 | https://doi.org/10.1371/journal.pntd.0003563

On the Road to Elimination of Rhodesiense Human African Trypanosomiasis: First WHO Meeting of Stakeholders

Peter Holmes

PLOS Neglected Tropical Diseases: published April 2, 2015 | https://doi.org/10.1371/journal.pntd.0003571

Historical Profiles and Perspectives

Historical Perspective: Snail Control to Prevent Schistosomiasis

Charles H. King, David Bertsch

PLOS Neglected Tropical Diseases: published April 23, 2015 | https://doi.org/10.1371/journal.pntd.0003657

Symposium

Case Report: A Retrospective Serological Analysis Indicating Human Exposure to Tick-Borne Relapsing Fever Spirochetes in Texas

Hannah K. Wilder, Edward Wozniak, Elizabeth Huddleston, Sri Ramya Tata, Nicholas C. Fitzkee, Job E. Lopez

PLOS Neglected Tropical Diseases: published April 9, 2015 | https://doi.org/10.1371/journal.pntd.0003617

Reviews

Reviewing Dengue: Still a Neglected Tropical Disease?

Olaf Horstick, Yesim Tozan, Annelies Wilder-Smith

PLOS Neglected Tropical Diseases: published April 30, 2015 | https://doi.org/10.1371/journal.pntd.0003632

Neglected Tropical Diseases among the Association of Southeast Asian Nations (ASEAN): Overview and Update

Peter J. Hotez, Maria Elena Bottazzi, Ulrich Strych, Li-Yen Chang, Yvonne A. L. Lim, Maureen M. Goodenow, Sazaly AbuBakar

PLOS Neglected Tropical Diseases: published April 16, 2015 | https://doi.org/10.1371/journal.pntd.0003575

Research Articles

The Association between Nutritional Status and Malaria in Children from a Rural Community in the Amazonian Region: A Longitudinal Study

Márcia Almeida Araújo Alexandre, Silvana Gomes Benzecry, Andre Machado Siqueira, Sheila Vitor-Silva, Gisely Cardoso Melo, Wuelton Marcelo Monteiro, Heitor Pons Leite, Marcus Vinícius Guimarães Lacerda, Maria das Graças Costa Alecrim

PLOS Neglected Tropical Diseases: published April 30, 2015 | https://doi.org/10.1371/journal.pntd.0003743

Model for End-Stage Liver Disease (MELD) Score as a Predictor and Monitor of Mortality in Patients with Vibrio vulnificus Necrotizing Skin and Soft Tissue Infections

Kuo-Chin Huang, Yao-Hung Tsai, Kuo-Chung Huang, Mel S. Lee

PLOS Neglected Tropical Diseases: published April 29, 2015 | https://doi.org/10.1371/journal.pntd.0003720

A Household Serosurvey to Estimate the Magnitude of a Dengue Outbreak in Mombasa, Kenya, 2013

Esther M. Ellis, John C. Neatherlin, Mark Delorey, Melvin Ochieng, Abdinoor Haji Mohamed, Daniel Ondari Mogeni, Elizabeth Hunsperger, Shem Patta, Stella Gikunju, Lilian Waiboic, Barry Fields, Victor Ofula, Samson Limbaso Konongoi, Brenda Torres-Velasquez, Nina Marano, Rosemary Sang, Harold S. Margolis, Joel M. Montgomery, Kay M. Tomashek

PLOS Neglected Tropical Diseases: published April 29, 2015 | https://doi.org/10.1371/journal.pntd.0003733

Frequent House Invasion of Trypanosoma cruzi-Infected Triatomines in a Suburban Area of Brazil

Gilmar Ribeiro Jr., Rodrigo Gurgel-Gonçalves, Renato Barbosa Reis, Carlos Gustavo Silva dos Santos, Alekhine Amorim, Sônia Gumes Andrade, Mitermayer G. Reis

PLOS Neglected Tropical Diseases: published April 24, 2015 | https://doi.org/10.1371/journal.pntd.0003678

Tissue Localization and Extracellular Matrix Degradation by PI, PII and PIII Snake Venom Metalloproteinases: Clues on the Mechanisms of Venom-Induced Hemorrhage

Cristina Herrera, Teresa Escalante, Mathieu-Benoit Voisin, Alexandra Rucavado, Diego Morazán, Jéssica Kele A. Macêdo, Juan J. Calvete, Libia Sanz, Sussan Nourshargh, José María Gutiérrez, Jay W. Fox

PLOS Neglected Tropical Diseases: published April 24, 2015 | https://doi.org/10.1371/journal.pntd.0003731

Bayesian Geostatistical Model-Based Estimates of Soil-Transmitted Helminth Infection in Nigeria, Including Annual Deworming Requirements

Akinola S. Oluwole, Uwem F. Ekpo, Dimitrios-Alexios Karagiannis-Voules, Eniola M. Abe, Francisca O. Olamiju, Sunday Isiyaku, Chukwu Okoronkwo, Yisa Saka, Obiageli J. Nebe, Eka I. Braide, Chiedu F. Mafiana, Jürg Utzinger, Penelope Vounatsou

PLOS Neglected Tropical Diseases: published April 24, 2015 | https://doi.org/10.1371/journal.pntd.0003740

Is Diabetes a Risk Factor for a Severe Clinical Presentation of Dengue? - Review and Meta-analysis

Nan Shwe Nwe Htun, Peter Odermatt, Ikenna C. Eze, Noémie Boillat-Blanco, Valérie D’Acremont, Nicole Probst-Hensch

PLOS Neglected Tropical Diseases: published April 24, 2015 | https://doi.org/10.1371/journal.pntd.0003741

Rapid Emergence of Multidrug Resistant, H58-Lineage Salmonella Typhi in Blantyre, Malawi

Nicholas A. Feasey, Katherine Gaskell, Vanessa Wong, Chisomo Msefula, George Selemani, Save Kumwenda, Theresa J. Allain, Jane Mallewa, Neil Kennedy, Aisleen Bennett, Joram O. Nyirongo, Patience A. Nyondo, Madalitso D. Zulu, Julian Parkhill, Gordon Dougan, Melita A. Gordon, Robert S. Heyderman

PLOS Neglected Tropical Diseases: published April 24, 2015 | https://doi.org/10.1371/journal.pntd.0003748

A Small Antigenic Determinant of the Chikungunya Virus E2 Protein Is Sufficient to Induce Neutralizing Antibodies which Are Partially Protective in Mice

Christopher Weber, Sarah M. Büchner, Barbara S. Schnierle

PLOS Neglected Tropical Diseases: published April 23, 2015 | https://doi.org/10.1371/journal.pntd.0003684

From Lab to Field: The Influence of Urban Landscapes on the Invasive Potential of Wolbachia in Brazilian Aedes aegypti Mosquitoes

Heverton Leandro Carneiro Dutra, Lilha Maria Barbosa dos Santos, Eric Pearce Caragata, Jéssica Barreto Lopes Silva, Daniel Antunes Maciel Villela, Rafael Maciel-de-Freitas, Luciano Andrade Moreira

PLOS Neglected Tropical Diseases: published April 23, 2015 | https://doi.org/10.1371/journal.pntd.0003689

Costs of Testing for Ocular Chlamydia trachomatis Infection Compared to Mass Drug Administration for Trachoma in The Gambia: Application of Results from the PRET Study

Emma Harding-Esch, Mireia Jofre-Bonet, Jaskiran K. Dhanjal, Sarah Burr, Tansy Edwards, Martin Holland, Ansumana Sillah, Sheila West, Tom Lietman, Jeremy Keenan, David Mabey, Robin Bailey

PLOS Neglected Tropical Diseases: published April 22, 2015 | https://doi.org/10.1371/journal.pntd.0003670

Identification of microRNA Genes in Three Opisthorchiids

Vladimir Y. Ovchinnikov, Dmitry A. Afonnikov, Gennady V. Vasiliev, Elena V. Kashina, Banchob Sripa, Viacheslav A. Mordvinov, Alexey V. Katokhin

PLOS Neglected Tropical Diseases: published April 21, 2015 | https://doi.org/10.1371/journal.pntd.0003680

Onchocerciasis Transmission in Ghana: Persistence under Different Control Strategies and the Role of the Simuliid Vectors

Poppy H. L. Lamberton, Robert A. Cheke, Peter Winskill, Iñaki Tirados, Martin Walker, Mike Y. Osei-Atweneboana, Nana-Kwadwo Biritwum, Anthony Tetteh-Kumah, Daniel A. Boakye, Michael D. Wilson, Rory J. Post, María-Gloria Basañez

PLOS Neglected Tropical Diseases: published April 21, 2015 | https://doi.org/10.1371/journal.pntd.0003688

Global Transcriptional Dynamics of Diapause Induction in Non-Blood-Fed and Blood-Fed Aedes albopictus

Xin Huang, Monica F. Poelchau, Peter A. Armbruster

PLOS Neglected Tropical Diseases: published April 21, 2015 | https://doi.org/10.1371/journal.pntd.0003724

Spatio-Temporal Distribution of Aedes aegypti (Diptera: Culicidae) Mitochondrial Lineages in Cities with Distinct Dengue Incidence Rates Suggests Complex Population Dynamics of the Dengue Vector in Colombia

Jeiczon Jaimes-Dueñez, Sair Arboleda, Omar Triana-Chávez, Andrés Gómez-Palacio

PLOS Neglected Tropical Diseases: published April 20, 2015 | https://doi.org/10.1371/journal.pntd.0003553

Social Pathways for Ebola Virus Disease in Rural Sierra Leone, and Some Implications for Containment

Paul Richards, Joseph Amara, Mariane C. Ferme, Prince Kamara, Esther Mokuwa, Amara Idara Sheriff, Roland Suluku, Maarten Voors

PLOS Neglected Tropical Diseases: published April 17, 2015 | https://doi.org/10.1371/journal.pntd.0003567

High Prevalence of HTLV-1 Infection among Japanese Immigrants in Non-endemic Area of Brazil

Larissa M. Bandeira, Silvia N. O. Uehara, Marcel A. Asato, Gabriela S. Aguena, Cristiane M. Maedo, Nikolas H. Benites, Marco A. M. Puga, Grazielli R. Rezende, Carolina M. Finotti, Gabriela A. Cesar, Tayana S. O. Tanaka, Vivianne O. L. Castro, Koko Otsuki, Ana C. P. Vicente, Carlos E. Fernandes, Ana R. C. Motta-Castro

PLOS Neglected Tropical Diseases: published April 17, 2015 | https://doi.org/10.1371/journal.pntd.0003691

Using Hospital Discharge Database to Characterize Chagas Disease Evolution in Spain: There Is a Need for a Systematic Approach towards Disease Detection and Control

Zaida Herrador, Eva Rivas, Alin Gherasim, Diana Gomez-Barroso, Jezabel García, Agustín Benito, Pilar Aparicio

PLOS Neglected Tropical Diseases: published April 17, 2015 | https://doi.org/10.1371/journal.pntd.0003710

Release of Lungworm Larvae from Snails in the Environment: Potential for Alternative Transmission Pathways

Alessio Giannelli, Vito Colella, Francesca Abramo, Rafael Antonio do Nascimento Ramos, Luigi Falsone, Emanuele Brianti, Antonio Varcasia, Filipe Dantas-Torres, Martin Knaus, Mark T. Fox, Domenico Otranto

PLOS Neglected Tropical Diseases: published April 17, 2015 | https://doi.org/10.1371/journal.pntd.0003722

A Recombinant Vesicular Stomatitis Virus-Based Lassa Fever Vaccine Protects Guinea Pigs and Macaques against Challenge with Geographically and Genetically Distinct Lassa Viruses

David Safronetz, Chad Mire, Kyle Rosenke, Friederike Feldmann, Elaine Haddock, Thomas Geisbert, Heinz Feldmann

PLOS Neglected Tropical Diseases: published April 17, 2015 | https://doi.org/10.1371/journal.pntd.0003736

Trypanosomiasis-Induced Megacolon Illustrates How Myenteric Neurons Modulate the Risk for Colon Cancer in Rats and Humans

Vinicius Kannen, Enio C. de Oliveira, Bruno Zene Motta, Annuar Jose Chaguri, Mariângela Ottoboni Brunaldi, Sérgio B. Garcia

PLOS Neglected Tropical Diseases: published April 17, 2015 | https://doi.org/10.1371/journal.pntd.0003744

Estimating the Global Burden of Endemic Canine Rabies

Katie Hampson, Laurent Coudeville, Tiziana Lembo, Maganga Sambo, Alexia Kieffer, Michaël Attlan, Jacques Barrat, Jesse D. Blanton, Deborah J. Briggs, Sarah Cleaveland, Peter Costa, Conrad M. Freuling, Elly Hiby, Lea Knopf, Fernando Leanes, François-Xavier Meslin, Artem Metlin, Mary Elizabeth Miranda, Thomas Müller, Louis H. Nel, Sergio Recuenco, Charles E. Rupprecht, Carolin Schumacher, Louise Taylor, Marco Antonio Natal Vigilato, Jakob Zinsstag, Jonathan Dushoff, on behalf of the Global Alliance for Rabies Control Partners for Rabies Prevention

PLOS Neglected Tropical Diseases: published April 16, 2015 | https://doi.org/10.1371/journal.pntd.0003709

Intravital Imaging of a Massive Lymphocyte Response in the Cortical Dura of Mice after Peripheral Infection by Trypanosomes

Jonathan A. Coles, Elmarie Myburgh, Ryan Ritchie, Alana Hamilton, Jean Rodgers, Jeremy C. Mottram, Michael P. Barrett, James M. Brewer

PLOS Neglected Tropical Diseases: published April 16, 2015 | https://doi.org/10.1371/journal.pntd.0003714

Shifts in the Spatiotemporal Dynamics of Schistosomiasis: A Case Study in Anhui Province, China

Yi Hu, Rui Li, Yue Chen, Fenghua Gao, Qizhi Wang, Shiqing Zhang, Zhijie Zhang, Qingwu Jiang

PLOS Neglected Tropical Diseases: published April 16, 2015 | https://doi.org/10.1371/journal.pntd.0003715

Estimating Dengue Transmission Intensity from Sero-Prevalence Surveys in Multiple Countries

Natsuko Imai, Ilaria Dorigatti, Simon Cauchemez, Neil M. Ferguson

PLOS Neglected Tropical Diseases: published April 16, 2015 | https://doi.org/10.1371/journal.pntd.0003719

Insensitivity to the Spatial Repellent Action of Transfluthrin in Aedes aegypti: A Heritable Trait Associated with Decreased Insecticide Susceptibility

Joseph M. Wagman, Nicole L. Achee, John P. Grieco

PLOS Neglected Tropical Diseases: published April 16, 2015 | https://doi.org/10.1371/journal.pntd.0003726

Case Report: Actinomycetoma Caused by Nocardia aobensis from Lao PDR with Favourable Outcome after Short-Term Antibiotic Treatment

Inthanomchanh Vongphoumy, David A. B. Dance, Sabine Dittrich, Julie Logan, Viengmon Davong, Sayaphet Rattanavong, Joerg Blessmann

PLOS Neglected Tropical Diseases: published April 16, 2015 | https://doi.org/10.1371/journal.pntd.0003729

Plasmodium vivax Populations Are More Genetically Diverse and Less Structured than Sympatric Plasmodium falciparum Populations

Charlie Jennison, Alicia Arnott, Natacha Tessier, Livingstone Tavul, Cristian Koepfli, Ingrid Felger, Peter M. Siba, John C. Reeder, Melanie Bahlo, Ivo Mueller, Alyssa E. Barry

PLOS Neglected Tropical Diseases: published April 15, 2015 | https://doi.org/10.1371/journal.pntd.0003634

Tsetse Fly (G.f. fuscipes) Distribution in the Lake Victoria Basin of Uganda

Mugenyi Albert, Nicola A Wardrop, Peter M Atkinson, Steve J Torr, Susan C Welburn

PLOS Neglected Tropical Diseases: published April 15, 2015 | https://doi.org/10.1371/journal.pntd.0003705

Overexpression of Cytoplasmic TcSIR2RP1 and Mitochondrial TcSIR2RP3 Impacts on Trypanosoma cruzi Growth and Cell Invasion

Carla Ritagliati, Victoria L. Alonso, Romina Manarin, Pamela Cribb, Esteban C. Serra

PLOS Neglected Tropical Diseases: published April 15, 2015 | https://doi.org/10.1371/journal.pntd.0003725

The Availability and Consistency of Dengue Surveillance Data Provided Online by the World Health Organization

Irene Ruberto, Ernesto Marques, Donald S. Burke, Willem G. Van Panhuis

PLOS Neglected Tropical Diseases: published April 14, 2015 | https://doi.org/10.1371/journal.pntd.0003511

Evaluation of Cell Binding Activities of Leptospira ECM Adhesins

Gregory T. Robbins, Beth L. Hahn, Karen V. Evangelista, Lavinia Padmore, Patrick S. Aranda, Jenifer Coburn

PLOS Neglected Tropical Diseases: published April 14, 2015 | https://doi.org/10.1371/journal.pntd.0003712

DNA Detection of Schistosoma japonicum: Diagnostic Validity of a LAMP Assay for Low-Intensity Infection and Effects of Chemotherapy in Humans

Jing Xu, Zhi-Xun Guan, Bo Zhao, Yan-Yan Wang, Yun Cao, Hui-Qin Zhang, Xing-Quan Zhu, Yong-Kang He, Chao-Ming Xia

PLOS Neglected Tropical Diseases: published April 13, 2015 | https://doi.org/10.1371/journal.pntd.0003668

Functionality of Dengue Virus Specific Memory T Cell Responses in Individuals Who Were Hospitalized or Who Had Mild or Subclinical Dengue Infection

Chandima Jeewandara, Thiruni N. Adikari, Laksiri Gomes, Samitha Fernando, R. H. Fernando, M. K. T. Perera, Dinuka Ariyaratne, Achala Kamaladasa, Maryam Salimi, Shamini Prathapan, Graham S. Ogg, Gathsaurie Neelika Malavige

PLOS Neglected Tropical Diseases: published April 13, 2015 | https://doi.org/10.1371/journal.pntd.0003673

A DNA Vaccine against Yellow Fever Virus: Development and Evaluation

Milton Maciel Jr., Fábia da Silva Pereira Cruz, Marli Tenório Cordeiro, Márcia Archer da Motta, Klécia Marília Soares de Melo Cassemiro, Rita de Cássia Carvalho Maia, Regina Célia Bressan Queiroz de Figueiredo, Ricardo Galler, Marcos da Silva Freire, Joseph Thomas August, Ernesto T. A. Marques, Rafael Dhalia

PLOS Neglected Tropical Diseases: published April 13, 2015 | https://doi.org/10.1371/journal.pntd.0003693

The Trypanosoma cruzi Vitamin C Dependent Peroxidase Confers Protection against Oxidative Stress but Is Not a Determinant of Virulence

Martin C. Taylor, Michael D. Lewis, Amanda Fortes Francisco, Shane R. Wilkinson, John M. Kelly

PLOS Neglected Tropical Diseases: published April 13, 2015 | https://doi.org/10.1371/journal.pntd.0003707

What Makes Community Engagement Effective?: Lessons from the Eliminate Dengue Program in Queensland Australia

Pamela A. Kolopack, Janet A. Parsons, James V. Lavery

PLOS Neglected Tropical Diseases: published April 13, 2015 | https://doi.org/10.1371/journal.pntd.0003713

The B Cell Adaptor Molecule Bam32 Is Critically Important for Optimal Antibody Response and Resistance to Trypanosoma congolense Infection in Mice

Chukwunonso Onyilagha, Ping Jia, Nipun Jayachandran, Sen Hou, Ifeoma Okwor, Shiby Kuriakose, Aaron Marshall, Jude E. Uzonna

PLOS Neglected Tropical Diseases: published April 13, 2015 | https://doi.org/10.1371/journal.pntd.0003716

Control of Trachoma in Australia: A Model Based Evaluation of Current Interventions

Andrew J. Shattock, Manoj Gambhir, Hugh R. Taylor, Carleigh S. Cowling, John M. Kaldor, David P. Wilson

PLOS Neglected Tropical Diseases: published April 10, 2015 | https://doi.org/10.1371/journal.pntd.0003474

Performance of Kala-Azar Surveillance in Gaffargaon Subdistrict of Mymensingh, Bangladesh

Kazi Mizanur Rahman, Indira V. M. Samarawickrema, David Harley, Anna Olsen, Colin D. Butler, Shariful Amin Sumon, Subrata Kumar Biswas, Stephen P. Luby, Adrian C. Sleigh

PLOS Neglected Tropical Diseases: published April 10, 2015 | https://doi.org/10.1371/journal.pntd.0003531

River Boats Contribute to the Regional Spread of the Dengue Vector Aedes aegypti in the Peruvian Amazon

Sarah Anne Guagliardo, Amy C. Morrison, Jose Luis Barboza, Edwin Requena, Helvio Astete, Gonzalo Vazquez-Prokopec, Uriel Kitron

PLOS Neglected Tropical Diseases: published April 10, 2015 | https://doi.org/10.1371/journal.pntd.0003648

Expression and Function of S100A8/A9 (Calprotectin) in Human Typhoid Fever and the Murine Salmonella Model

Hanna K. De Jong, Ahmed Achouiti, Gavin C. K. W. Koh, Christopher M. Parry, Stephen Baker, Mohammed Abul Faiz, Jaap T. van Dissel, Albert M. Vollaard, Ester M. M. van Leeuwen, Joris J. T. H. Roelofs, Alex F. de Vos, Johannes Roth, Tom van der Poll, Thomas Vogl, Willem Joost Wiersinga

PLOS Neglected Tropical Diseases: published April 10, 2015 | https://doi.org/10.1371/journal.pntd.0003663

Control, Elimination, and Eradication of River Blindness: Scenarios, Timelines, and Ivermectin Treatment Needs in Africa

Young Eun Kim, Jan H. F. Remme, Peter Steinmann, Wilma A. Stolk, Jean-Baptiste Roungou, Fabrizio Tediosi

PLOS Neglected Tropical Diseases: published April 10, 2015 | https://doi.org/10.1371/journal.pntd.0003664

Development of Ss-NIE-1 Recombinant Antigen Based Assays for Immunodiagnosis of Strongyloidiasis

Lisa N. Rascoe, Courtney Price, Sun Hee Shin, Isabel McAuliffe, Jeffrey W. Priest, Sukwan Handali

PLOS Neglected Tropical Diseases: published April 10, 2015 | https://doi.org/10.1371/journal.pntd.0003694

Down Regulation of NO Signaling in Trypanosoma cruzi upon Parasite-Extracellular Matrix Interaction: Changes in Protein Modification by Nitrosylation and Nitration

Milton Pereira, Chrislaine Soares, Gisele André Baptista Canuto, Marina Franco Maggi Tavares, Walter Colli, Maria Julia M. Alves

PLOS Neglected Tropical Diseases: published April 9, 2015 | https://doi.org/10.1371/journal.pntd.0003683

From Health Advice to Taboo: Community Perspectives on the Treatment of Sleeping Sickness in the Democratic Republic of Congo, a Qualitative Study

Alain Mpanya, David Hendrickx, Sylvain Baloji, Crispin Lumbala, Raquel Inocêncio da Luz, Marleen Boelaert, Pascal Lutumba

PLOS Neglected Tropical Diseases: published April 9, 2015 | https://doi.org/10.1371/journal.pntd.0003686

Recombinant Adeno-Vaccine Expressing Enterovirus 71-Like Particles against Hand, Foot, and Mouth Disease

Yueh-Liang Tsou, Yi-Wen Lin, Hsiao-Yun Shao, Shu-Ling Yu, Shang-Rung Wu, Hsiao-Yu Lin, Chia-Chyi Liu, Chieh Huang, Pele Chong, Yen-Hung Chow

PLOS Neglected Tropical Diseases: published April 9, 2015 | https://doi.org/10.1371/journal.pntd.0003692

Community-Centered Responses to Ebola in Urban Liberia: The View from Below

Sharon Alane Abramowitz, Kristen E. McLean, Sarah Lindley McKune, Kevin Louis Bardosh, Mosoka Fallah, Josephine Monger, Kodjo Tehoungue, Patricia A. Omidian

PLOS Neglected Tropical Diseases: published April 9, 2015 | https://doi.org/10.1371/journal.pntd.0003706

Immune Protection against Trypanosoma cruzi Induced by TcVac4 in a Canine Model

José E. Aparicio-Burgos, José A. Zepeda-Escobar, Roberto Montes de Oca-Jimenez, José G. Estrada-Franco, Alberto Barbabosa-Pliego, Laucel Ochoa-García, Ricardo Alejandre-Aguilar, Nancy Rivas, Giovanna Peñuelas-Rivas, Margarita Val-Arreola, Shivali Gupta, Felix Salazar-García, Nisha J. Garg, Juan C. Vázquez-Chagoyán

PLOS Neglected Tropical Diseases: published April 8, 2015 | https://doi.org/10.1371/journal.pntd.0003625

Deep Sequencing of the Trypanosoma cruzi GP63 Surface Proteases Reveals Diversity and Diversifying Selection among Chronic and Congenital Chagas Disease Patients

Martin S. Llewellyn, Louisa A. Messenger, Alejandro O. Luquetti, Lineth Garcia, Faustino Torrico, Suelene B. N. Tavares, Bachar Cheaib, Nicolas Derome, Marc Delepine, Céline Baulard, Jean-Francois Deleuze, Sascha Sauer, Michael A. Miles

PLOS Neglected Tropical Diseases: published April 7, 2015 | https://doi.org/10.1371/journal.pntd.0003458

Nucleosides Present on Phlebotomine Saliva Induce Immunossuppression and Promote the Infection Establishment

Vanessa Carregaro, José M. Ribeiro, Jesus G. Valenzuela, Djalma L. Souza-Júnior, Diego L. Costa, Carlo J. F. Oliveira, Laís A. Sacramento, Manuela S. L. Nascimento, Cristiane M. Milanezi, Fernando Q. Cunha, João S. Silva

PLOS Neglected Tropical Diseases: published April 7, 2015 | https://doi.org/10.1371/journal.pntd.0003600

Typhoid Fever in Young Children in Bangladesh: Clinical Findings, Antibiotic Susceptibility Pattern and Immune Responses

Farhana Khanam, Md. Abu Sayeed, Feroza Kaneez Choudhury, Alaullah Sheikh, Dilruba Ahmed, Doli Goswami, Md. Lokman Hossain, Abdullah Brooks, Stephen B. Calderwood, Richelle C. Charles, Alejandro Cravioto, Edward T. Ryan, Firdausi Qadri

PLOS Neglected Tropical Diseases: published April 7, 2015 | https://doi.org/10.1371/journal.pntd.0003619

High Seroprevalence for Spotted Fever Group Rickettsiae, Is Associated with Higher Temperatures and Rural Environment in Mbeya Region, Southwestern Tanzania

Norbert Heinrich, Tatjana Dill, Gerhard Dobler, Petra Clowes, Inge Kroidl, Mandy Starke, Nyanda Elias Ntinginya, Leonard Maboko, Thomas Löscher, Michael Hoelscher, Elmar Saathoff

PLOS Neglected Tropical Diseases: published April 7, 2015 | https://doi.org/10.1371/journal.pntd.0003626

Autophagy Protects Monocytes from Wolbachia Heat Shock Protein 60–Induced Apoptosis and Senescence

Vijayan Kamalakannan, Abijit Shiny, Subash Babu, Rangarajan Badri Narayanan

PLOS Neglected Tropical Diseases: published April 7, 2015 | https://doi.org/10.1371/journal.pntd.0003675

How Long Can Stool Samples Be Fixed for an Accurate Diagnosis of Soil-Transmitted Helminth Infection Using Mini-FLOTAC?

Beatrice Barda, Marco Albonico, Davide Ianniello, Shaali M. Ame, Jennifer Keiser, Benjamin Speich, Laura Rinaldi, Giuseppe Cringoli, Roberto Burioni, Antonio Montresor, Jürg Utzinger

PLOS Neglected Tropical Diseases: published April 7, 2015 | https://doi.org/10.1371/journal.pntd.0003698

Mosquito-Disseminated Pyriproxyfen Yields High Breeding-Site Coverage and Boosts Juvenile Mosquito Mortality at the Neighborhood Scale

Fernando Abad-Franch, Elvira Zamora-Perea, Gonçalo Ferraz, Samael D. Padilla-Torres, Sérgio L. B. Luz

PLOS Neglected Tropical Diseases: published April 7, 2015 | https://doi.org/10.1371/journal.pntd.0003702

Fitness of Leishmania donovani Parasites Resistant to Drug Combinations

Raquel García-Hernández, Verónica Gómez-Pérez, Santiago Castanys, Francisco Gamarro

PLOS Neglected Tropical Diseases: published April 7, 2015 | https://doi.org/10.1371/journal.pntd.0003704

Sensitivity and Specificity of a Novel Classifier for the Early Diagnosis of Dengue

Nguyen Minh Tuan, Ho Thi Nhan, Nguyen Van Vinh Chau, Nguyen Thanh Hung, Ha Manh Tuan, Ta Van Tram, Nguyen Le Da Ha, Phan Loi, Han Khoi Quang, Duong Thi Hue Kien, Sonya Hubbard, Tran Nguyen Bich Chau, Bridget Wills, Marcel Wolbers, Cameron P. Simmons

PLOS Neglected Tropical Diseases: published April 2, 2015 | https://doi.org/10.1371/journal.pntd.0003638

Distribution and Risk Factors for Plasmodium and Helminth Co-infections: A Cross-Sectional Survey among Children in Bagamoyo District, Coastal Region of Tanzania

Nahya Salim, Stefanie Knopp, Omar Lweno, Ummi Abdul, Ali Mohamed, Tobias Schindler, Julian Rothen, John Masimba, Denis Kwaba, Alisa S. Mohammed, Fabrice Althaus, Salim Abdulla, Marcel Tanner, Claudia Daubenberger, Blaise Genton

PLOS Neglected Tropical Diseases: published April 2, 2015 | https://doi.org/10.1371/journal.pntd.0003660

Effectiveness and Safety of Short Course Liposomal Amphotericin B (AmBisome) as First Line Treatment for Visceral Leishmaniasis in Bangladesh

Emiliano Lucero, Simon M. Collin, Sujit Gomes, Fatima Akter, Asaduzzam Asad, Asish Kumar Das, Koert Ritmeijer

PLOS Neglected Tropical Diseases: published April 2, 2015 | https://doi.org/10.1371/journal.pntd.0003699

Capsules, Toxins and AtxA as Virulence Factors of Emerging Bacillus cereus Biovar anthracis

Christophe Brézillon, Michel Haustant, Susann Dupke, Jean-Philippe Corre, Angelika Lander, Tatjana Franz, Marc Monot, Evelyne Couture-Tosi, Gregory Jouvion, Fabian H. Leendertz, Roland Grunow, Michèle E. Mock, Silke R. Klee, Pierre L. Goossens

PLOS Neglected Tropical Diseases: published April 1, 2015 | https://doi.org/10.1371/journal.pntd.0003455

Development of a Dry-Reagent-Based qPCR to Facilitate the Diagnosis of Mycobacterium ulcerans Infection in Endemic Countries

Jérémie Babonneau, Christian Bernard, Estelle Marion, Annick Chauty, Marie Kempf, Raymond Robert, Laurent Marsollier, Franco-Beninese Buruli Research Group Benin:

PLOS Neglected Tropical Diseases: published April 1, 2015 | https://doi.org/10.1371/journal.pntd.0003606

The Prevalence of Human T-Lymphotropic Virus Infection among Blood Donors in Southeast China, 2004-2013

Jinzhen Xie, Shengxiang Ge, Yali Zhang, Yongcai Lin, Hongying Ni, Jun Zhang, Changrong Chen

PLOS Neglected Tropical Diseases: published April 1, 2015 | https://doi.org/10.1371/journal.pntd.0003685

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