February 2015

The sandfly Phlebotomus papatasi is the vector of Leishmania major, which is responsible for most cases of Old World cutaneous leishmaniasis in Saudi Arabia. In endemic areas, people can be exposed to hundreds of bites every night, thus increasing their risk of contracting the disease. Sandflies inject saliva while feeding and the salivary protein PpSP32 was previously shown to be a biomarker for bite exposure. The authors used recombinant PpSP32 to study the association between antibody response to saliva and disease outcome. See Acosta-Serrano et al.

Image Credit: Mondragon-Shem K.

Editorials

PLOS Neglected Tropical Diseases 2014 Reviewer Thank You

PLOS Neglected Tropical Diseases: published February 27, 2015 | https://doi.org/10.1371/journal.pntd.0003621

The Gulf of Mexico: A “Hot Zone” for Neglected Tropical Diseases?

Peter J. Hotez, Maria Elena Bottazzi, Eric Dumonteil, Pierre Buekens

PLOS Neglected Tropical Diseases: published February 26, 2015 | https://doi.org/10.1371/journal.pntd.0003481

Viewpoints

It’s Time to Dispel the Myth of “Asymptomatic” Schistosomiasis

Charles H. King

PLOS Neglected Tropical Diseases: published February 19, 2015 | https://doi.org/10.1371/journal.pntd.0003504

The Newest “Omics”—Metagenomics and Metabolomics—Enter the Battle against the Neglected Tropical Diseases

Geoffrey A. Preidis, Peter J. Hotez

PLOS Neglected Tropical Diseases: published February 12, 2015 | https://doi.org/10.1371/journal.pntd.0003382

Is Strongyloidiasis Endemic in Spain?

Angela Martinez-Perez, Rogelio Lopez-Velez

PLOS Neglected Tropical Diseases: published February 5, 2015 | https://doi.org/10.1371/journal.pntd.0003482

From Innovation to Application

Integrating Data and Resources on Neglected Tropical Diseases for Better Planning: The NTD Mapping Tool (NTDmap.org)

Rebecca M. Flueckiger, Birgit Nikolay, Huub C. Gelderblom, Jennifer L. Smith, Danny Haddad, Wesley Tack, Guy Hendrickx, David Addiss, Jorge Cano, Danny R. Hatcher, Adrian Hopkins, Rachel L. Pullan, Alex Pavluck, Eric Ottesen, Simon J. Brooker

PLOS Neglected Tropical Diseases: published February 5, 2015 | https://doi.org/10.1371/journal.pntd.0003400

Review

A Literature Review of Economic Evaluations for a Neglected Tropical Disease: Human African Trypanosomiasis (“Sleeping Sickness”)

C. Simone Sutherland, Joshua Yukich, Ron Goeree, Fabrizio Tediosi

PLOS Neglected Tropical Diseases: published February 5, 2015 | https://doi.org/10.1371/journal.pntd.0003397

Research Articles

Follow-up of an Asymptomatic Chagas Disease Population of Children after Treatment with Nifurtimox (Lampit) in a Sylvatic Endemic Transmission Area of Colombia

Fiorella Bianchi, Zulma Cucunubá, Felipe Guhl, Nadia Lorena González, Hector Freilij, Rubén Santiago Nicholls, Juan David Ramírez, Marleny Montilla, Astrid Carolina Flórez, Fernando Rosas, Victor Saavedra, Nubia Silva

PLOS Neglected Tropical Diseases: published February 27, 2015 | https://doi.org/10.1371/journal.pntd.0003465

Health Economic Evaluations of Visceral Leishmaniasis Treatments: A Systematic Review

Daniel S. Marinho, Carmen N. P. R. Casas, Claudia C. de A. Pereira, Iuri C. Leite

PLOS Neglected Tropical Diseases: published February 27, 2015 | https://doi.org/10.1371/journal.pntd.0003527

Inter-epidemic Acquisition of Rift Valley Fever Virus in Humans in Tanzania

Robert David Sumaye, Emmanuel Nji Abatih, Etienne Thiry, Mbaraka Amuri, Dirk Berkvens, Eveline Geubbels

PLOS Neglected Tropical Diseases: published February 27, 2015 | https://doi.org/10.1371/journal.pntd.0003536

Sm29, but Not Sm22.6 Retains its Ability to Induce a Protective Immune Response in Mice Previously Exposed to a Schistosoma mansoni Infection

Clarice Carvalho Alves, Neusa Araujo, Viviane Cristina Fernandes dos Santos, Flávia Bubula Couto, Natan R. G. Assis, Suellen B. Morais, Sérgio Costa Oliveira, Cristina Toscano Fonseca

PLOS Neglected Tropical Diseases: published February 27, 2015 | https://doi.org/10.1371/journal.pntd.0003537

A Novel Bacterial Pathogen of Biomphalaria glabrata: A Potential Weapon for Schistosomiasis Control?

David Duval, Richard Galinier, Gabriel Mouahid, Eve Toulza, Jean François Allienne, Julien Portela, Christophe Calvayrac, Anne Rognon, Nathalie Arancibia, Guillaume Mitta, André Théron, Benjamin Gourbal

PLOS Neglected Tropical Diseases: published February 26, 2015 | https://doi.org/10.1371/journal.pntd.0003489

Minipool Caprylic Acid Fractionation of Plasma Using Disposable Equipment: A Practical Method to Enhance Immunoglobulin Supply in Developing Countries

Magdy El-Ekiaby, Mariángela Vargas, Makram Sayed, George Gorgy, Hadi Goubran, Mirjana Radosevic, Thierry Burnouf

PLOS Neglected Tropical Diseases: published February 26, 2015 | https://doi.org/10.1371/journal.pntd.0003501

Species-Specific Antimonial Sensitivity in Leishmania Is Driven by Post-Transcriptional Regulation of AQP1

Goutam Mandal, Srotoswati Mandal, Mansi Sharma, Karen Santos Charret, Barbara Papadopoulou, Hiranmoy Bhattacharjee, Rita Mukhopadhyay

PLOS Neglected Tropical Diseases: published February 25, 2015 | https://doi.org/10.1371/journal.pntd.0003500

Serology for Trachoma Surveillance after Cessation of Mass Drug Administration

Diana L. Martin, Rhiannon Bid, Frank Sandi, E. Brook Goodhew, Patrick A. Massae, Augustin Lasway, Heiko Philippin, William Makupa, Sandra Molina, Martin J. Holland, David C. W. Mabey, Chris Drakeley, Patrick J. Lammie, Anthony W. Solomon

PLOS Neglected Tropical Diseases: published February 25, 2015 | https://doi.org/10.1371/journal.pntd.0003555

Rapid Diagnostic Tests for Dengue Virus Infection in Febrile Cambodian Children: Diagnostic Accuracy and Incorporation into Diagnostic Algorithms

Michael J. Carter, Kate R. Emary, Catherine E. Moore, Christopher M. Parry, Soeng Sona, Hor Putchhat, Sin Reaksmey, Ngoun Chanpheaktra, Nicole Stoesser, Andrew D. M. Dobson, Nicholas P. J. Day, Varun Kumar, Stuart D. Blacksell

PLOS Neglected Tropical Diseases: published February 24, 2015 | https://doi.org/10.1371/journal.pntd.0003424

Leishmania infantum Amastigotes Trigger a Subpopulation of Human B Cells with an Immunoregulatory Phenotype

Guadalupe Andreani, Michel Ouellet, Rym Menasria, Alejandro Martin Gomez, Corinne Barat, Michel J. Tremblay

PLOS Neglected Tropical Diseases: published February 24, 2015 | https://doi.org/10.1371/journal.pntd.0003543

Screening Diagnostic Candidates for Schistosomiasis from Tegument Proteins of Adult Schistosoma japonicum Using an Immunoproteomic Approach

Min Zhang, Zhiqiang Fu, Changjian Li, Yanhui Han, Xiaodan Cao, Hongxiao Han, Yantao Liu, Ke Lu, Yang Hong, Jiaojiao Lin

PLOS Neglected Tropical Diseases: published February 23, 2015 | https://doi.org/10.1371/journal.pntd.0003454

Comparison of Two Quantitative Real Time PCR Assays for Rickettsia Detection in Patients from Tunisia

Abir Znazen, Hanen Sellami, Emna Elleuch, Zouhour Hattab, Laroussi Ben Sassi, Fatma Khrouf, Hassen Dammak, Amel Letaief, Mounir Ben Jemaa, Adnene Hammami

PLOS Neglected Tropical Diseases: published February 23, 2015 | https://doi.org/10.1371/journal.pntd.0003487

Bartonella spp. in Fruit Bats and Blood-Feeding Ectoparasites in Madagascar

Cara E. Brook, Ying Bai, Andrew P. Dobson, Lynn M. Osikowicz, Hafaliana C. Ranaivoson, Qiyun Zhu, Michael Y. Kosoy, Katharina Dittmar

PLOS Neglected Tropical Diseases: published February 23, 2015 | https://doi.org/10.1371/journal.pntd.0003532

Rapid Treponema pallidum Clearance from Blood and Ulcer Samples following Single Dose Benzathine Penicillin Treatment of Early Syphilis

Craig Tipple, Rachael Jones, Myra McClure, Graham Taylor

PLOS Neglected Tropical Diseases: published February 20, 2015 | https://doi.org/10.1371/journal.pntd.0003492

Epidemiology and Molecular Characterization of Cryptosporidium spp. in Humans, Wild Primates, and Domesticated Animals in the Greater Gombe Ecosystem, Tanzania

Michele B. Parsons, Dominic Travis, Elizabeth V. Lonsdorf, Iddi Lipende, Dawn M. Anthony Roellig, Shadrack Kamenya, Hongwei Zhang, Lihua Xiao, Thomas R. Gillespie

PLOS Neglected Tropical Diseases: published February 20, 2015 | https://doi.org/10.1371/journal.pntd.0003529

Repurposing Auranofin as a Lead Candidate for Treatment of Lymphatic Filariasis and Onchocerciasis

Christina A. Bulman, Chelsea M. Bidlow, Sara Lustigman, Fidelis Cho-Ngwa, David Williams, Alberto A. Rascón, Jr, Nancy Tricoche, Moses Samje, Aaron Bell, Brian Suzuki, K. C. Lim, Nonglak Supakorndej, Prasit Supakorndej, Alan R. Wolfe, Giselle M. Knudsen, Steven Chen, Chris Wilson, Kean-Hooi Ang, Michelle Arkin, Jiri Gut, Chris Franklin, Chris Marcellino, James H. McKerrow, Anjan Debnath, Judy A. Sakanari

PLOS Neglected Tropical Diseases: published February 20, 2015 | https://doi.org/10.1371/journal.pntd.0003534

High Prevalence of Tropheryma whipplei in Lao Kindergarten Children

Alpha Kabinet Keita, Audrey Dubot-Pérès, Koukeo Phommasone, Bountoy Sibounheuang, Manivanh Vongsouvath, Mayfong Mayxay, Didier Raoult, Paul N. Newton, Florence Fenollar

PLOS Neglected Tropical Diseases: published February 20, 2015 | https://doi.org/10.1371/journal.pntd.0003538

Genetic Diversity and Population Structure of Trypanosoma brucei in Uganda: Implications for the Epidemiology of Sleeping Sickness and Nagana

Richard Echodu, Mark Sistrom, Rosemary Bateta, Grace Murilla, Loyce Okedi, Serap Aksoy, Chineme Enyioha, John Enyaru, Elizabeth Opiyo, Wendy Gibson, Adalgisa Caccone

PLOS Neglected Tropical Diseases: published February 19, 2015 | https://doi.org/10.1371/journal.pntd.0003353

Analysis of Nematode Motion Using an Improved Light-Scatter Based System

Chuck S. Nutting, Rob R. Eversole, Kevin Blair, Sabine Specht, Thomas B. Nutman, Amy D. Klion, Samuel Wanji, Michel Boussinesq, Charles D. Mackenzie

PLOS Neglected Tropical Diseases: published February 19, 2015 | https://doi.org/10.1371/journal.pntd.0003523

Toxoplasmosis and Epilepsy — Systematic Review and Meta Analysis

Edgard B. Ngoungou, Devender Bhalla, Amandine Nzoghe, Marie-Laure Dardé, Pierre-Marie Preux

PLOS Neglected Tropical Diseases: published February 19, 2015 | https://doi.org/10.1371/journal.pntd.0003525

Regulation of Leishmania (L.) amazonensis Protein Expression by Host T Cell Dependent Responses: Differential Expression of Oligopeptidase B, Tryparedoxin Peroxidase and HSP70 Isoforms in Amastigotes Isolated from BALB/c and BALB/c Nude Mice

Priscila Camillo Teixeira, Leonardo Garcia Velasquez, Ana Paula Lepique, Eloiza de Rezende, José Matheus Camargo Bonatto, Marcello Andre Barcinski, Edecio Cunha-Neto, Beatriz Simonsen Stolf

PLOS Neglected Tropical Diseases: published February 18, 2015 | https://doi.org/10.1371/journal.pntd.0003411

The Spatiotemporal Expansion of Human Rabies and Its Probable Explanation in Mainland China, 2004-2013

Hong-Wu Yao, Yang Yang, Kun Liu, Xin-Lou Li, Shu-Qing Zuo, Ruo-Xi Sun, Li-Qun Fang, Wu-Chun Cao

PLOS Neglected Tropical Diseases: published February 18, 2015 | https://doi.org/10.1371/journal.pntd.0003502

Intrachromosomal Amplification, Locus Deletion and Point Mutation in the Aquaglyceroporin AQP1 Gene in Antimony Resistant Leishmania (Viannia) guyanensis

Rubens Monte-Neto, Marie-Claude N. Laffitte, Philippe Leprohon, Priscila Reis, Frédéric Frézard, Marc Ouellette

PLOS Neglected Tropical Diseases: published February 13, 2015 | https://doi.org/10.1371/journal.pntd.0003476

Tribendimidine: Mode of Action and nAChR Subtype Selectivity in Ascaris and Oesophagostomum

Alan P. Robertson, Sreekanth Puttachary, Samuel K. Buxton, Richard J. Martin

PLOS Neglected Tropical Diseases: published February 13, 2015 | https://doi.org/10.1371/journal.pntd.0003495

Anopheles Midgut Epithelium Evades Human Complement Activity by Capturing Factor H from the Blood Meal

Ayman Khattab, Marta Barroso, Tiera Miettinen, Seppo Meri

PLOS Neglected Tropical Diseases: published February 13, 2015 | https://doi.org/10.1371/journal.pntd.0003513

Immunodiagnosis of Paracoccidioidomycosis due to Paracoccidioides brasiliensis Using a Latex Test: Detection of Specific Antibody Anti-gp43 and Specific Antigen gp43

Priscila Oliveira dos Santos, Anderson Messias Rodrigues, Geisa Ferreira Fernandes, Silvia Helena Marques da Silva, Eva Burger, Zoilo Pires de Camargo

PLOS Neglected Tropical Diseases: published February 13, 2015 | https://doi.org/10.1371/journal.pntd.0003516

Households as Foci for Dengue Transmission in Highly Urban Vietnam

Katherine L. Anders, Le Hong Nga, Nguyen Thi Van Thuy, Tran Van Ngoc, Cao Thi Tam, Luong Thi Hue Tai, Nguyen Thanh Truong, Huynh Thi Le Duyen, Vu Tuan Trung, Duong Thi Hue Kien, Marcel Wolbers, Bridget Wills, Nguyen Van Vinh Chau, Nguyen Dac Tho, Cameron P. Simmons

PLOS Neglected Tropical Diseases: published February 13, 2015 | https://doi.org/10.1371/journal.pntd.0003528

Prevalence of Chagas Disease in Latin-American Migrants Living in Europe: A Systematic Review and Meta-analysis

Ana Requena-Méndez, Edelweiss Aldasoro, Elisa de Lazzari, Elisa Sicuri, Michael Brown, David A. J. Moore, Joaquim Gascon, Jose Muñoz

PLOS Neglected Tropical Diseases: published February 13, 2015 | https://doi.org/10.1371/journal.pntd.0003540

Generation of Luciferase-Expressing Leishmania infantum chagasi and Assessment of Miltefosine Efficacy in Infected Hamsters through Bioimaging

Juliana Q. Reimão, Jordana C. Oliveira, Cristiana T. Trinconi, Paulo C. Cotrim, Adriano C. Coelho, Silvia R. B. Uliana

PLOS Neglected Tropical Diseases: published February 13, 2015 | https://doi.org/10.1371/journal.pntd.0003556

Genetically Modifying the Insect Gut Microbiota to Control Chagas Disease Vectors through Systemic RNAi

Mabel L. Taracena, Pedro L. Oliveira, Olivia Almendares, Claudia Umaña, Carl Lowenberger, Ellen M. Dotson, Gabriela O. Paiva-Silva, Pamela M. Pennington

PLOS Neglected Tropical Diseases: published February 12, 2015 | https://doi.org/10.1371/journal.pntd.0003358

CD8+ T Lymphocyte Expansion, Proliferation and Activation in Dengue Fever

Andréia Manso de Matos, Karina Inacio Carvalho, Daniela Santoro Rosa, Lucy Santos Villas-Boas, Wanessa Cardoso da Silva, Célia Luiza de Lima Rodrigues, Olímpia Massae Nakasone Peel Furtado Oliveira, José Eduardo Levi, Evaldo Stanislau Affonso Araújo, Claudio Sergio Pannuti, Expedito José Albuquerque Luna, Esper George Kallas

PLOS Neglected Tropical Diseases: published February 12, 2015 | https://doi.org/10.1371/journal.pntd.0003520

Low-level Laser Therapy to the Mouse Femur Enhances the Fungicidal Response of Neutrophils against Paracoccidioides brasiliensis

Eva Burger, Ana Carolina S. C. Mendes, Giulia M. A. C. Bani, Maísa R. P. L. Brigagão, Gérsika B. Santos, Luiz Cosme C. Malaquias, Jorge Kleber Chavasco, Liana M. Verinaud, Zoilo P. de Camargo, Michael R. Hamblin, Felipe F. Sperandio

PLOS Neglected Tropical Diseases: published February 12, 2015 | https://doi.org/10.1371/journal.pntd.0003541

Trypanosoma cruzi Infection Is a Potent Risk Factor for Non-alcoholic Steatohepatitis Enhancing Local and Systemic Inflammation Associated with Strong Oxidative Stress and Metabolic Disorders

Luisina I. Onofrio, Alfredo R. Arocena, Augusto F. Paroli, María E. Cabalén, Marta C. Andrada, Roxana C. Cano, Susana Gea

PLOS Neglected Tropical Diseases: published February 10, 2015 | https://doi.org/10.1371/journal.pntd.0003464

Surveillance of Aedes aegypti: Comparison of House Index with Four Alternative Traps

Claudia T. Codeço, Arthur W. S. Lima, Simone C. Araújo, José Bento P. Lima, Rafael Maciel-de-Freitas, Nildimar A. Honório, Allan K. R. Galardo, Ima A. Braga, Giovanini E. Coelho, Denise Valle

PLOS Neglected Tropical Diseases: published February 10, 2015 | https://doi.org/10.1371/journal.pntd.0003475

Identification of the Mycobacterium ulcerans Protein MUL_3720 as a Promising Target for the Development of a Diagnostic Test for Buruli Ulcer

Anita Dreyer, Katharina Röltgen, Jean Pierre Dangy, Marie Thérèse Ruf, Nicole Scherr, Miriam Bolz, Nicholas Jay Tobias, Charles Moes, Andrea Vettiger, Timothy Paul Stinear, Gerd Pluschke

PLOS Neglected Tropical Diseases: published February 10, 2015 | https://doi.org/10.1371/journal.pntd.0003477

Accuracy of Five Serologic Tests for the Follow up of Strongyloides stercoralis Infection

Dora Buonfrate, Marco Sequi, Rojelio Mejia, Ruben O. Cimino, Alejandro J. Krolewiecki, Marco Albonico, Monica Degani, Stefano Tais, Andrea Angheben, Ana Requena-Mendez, José Muñoz, Thomas B. Nutman, Zeno Bisoffi

PLOS Neglected Tropical Diseases: published February 10, 2015 | https://doi.org/10.1371/journal.pntd.0003491

Neutralizing Dengue Antibody in Pregnant Thai Women and Cord Blood

Kriangsak Khamim, Weerawan Hattasingh, Ananda Nisalak, Jaranit Kaewkungwal, Stefan Fernandez, Butsaya Thaisomboonsuk, Krisana Pengsaa, Usa Thisyakorn

PLOS Neglected Tropical Diseases: published February 6, 2015 | https://doi.org/10.1371/journal.pntd.0003396

Genetic Diversity of Staphylococcus aureus in Buruli Ulcer

Nana Ama Amissah, Corinna Glasner, Anthony Ablordey, Caitlin S. Tetteh, Nana Konama Kotey, Isaac Prah, Tjip S. van der Werf, John W. Rossen, Jan Maarten van Dijl, Ymkje Stienstra

PLOS Neglected Tropical Diseases: published February 6, 2015 | https://doi.org/10.1371/journal.pntd.0003421

High Rates of O’Nyong Nyong and Chikungunya Virus Transmission in Coastal Kenya

A. Desiree LaBeaud, Tamara Banda, Julie Brichard, Eric M. Muchiri, Peter L. Mungai, Francis M. Mutuku, Erin Borland, Ginny Gildengorin, Sarah Pfeil, Crystal Y. Teng, Kristin Long, Mark Heise, Ann M. Powers, Uriel Kitron, Charles H. King

PLOS Neglected Tropical Diseases: published February 6, 2015 | https://doi.org/10.1371/journal.pntd.0003436

Description of a Nanobody-based Competitive Immunoassay to Detect Tsetse Fly Exposure

Guy Caljon, Shahid Hussain, Lieve Vermeiren, Jan Van Den Abbeele

PLOS Neglected Tropical Diseases: published February 6, 2015 | https://doi.org/10.1371/journal.pntd.0003456

Comparison of Vector Competence of Aedes mediovittatus and Aedes aegypti for Dengue Virus: Implications for Dengue Control in the Caribbean

B. Katherine Poole-Smith, Ryan R. Hemme, Mark Delorey, Gilberto Felix, Andrea L. Gonzalez, Manuel Amador, Elizabeth A. Hunsperger, Roberto Barrera

PLOS Neglected Tropical Diseases: published February 6, 2015 | https://doi.org/10.1371/journal.pntd.0003462

Spatio-temporal Transmission and Environmental Determinants of Schistosomiasis Japonica in Anhui Province, China

Yi Hu, Rui Li, Robert Bergquist, Henry Lynn, Fenghua Gao, Qizhi Wang, Shiqing Zhang, Liqian Sun, Zhijie Zhang, Qingwu Jiang

PLOS Neglected Tropical Diseases: published February 6, 2015 | https://doi.org/10.1371/journal.pntd.0003470

Detection of Rickettsia spp in Ticks by MALDI-TOF MS

Amina Yssouf, Lionel Almeras, Jérôme Terras, Cristina Socolovschi, Didier Raoult, Philippe Parola

PLOS Neglected Tropical Diseases: published February 6, 2015 | https://doi.org/10.1371/journal.pntd.0003473

The Emergence of Resistance to the Benzimidazole Anthlemintics in Parasitic Nematodes of Livestock Is Characterised by Multiple Independent Hard and Soft Selective Sweeps

Elizabeth Redman, Fiona Whitelaw, Andrew Tait, Charlotte Burgess, Yvonne Bartley, Philip John Skuce, Frank Jackson, John Stuart Gilleard

PLOS Neglected Tropical Diseases: published February 6, 2015 | https://doi.org/10.1371/journal.pntd.0003494

Mycobacterium Ulcerans Treatment – Can Antibiotic Duration Be Reduced in Selected Patients?

Raquel Cowan, Eugene Athan, N. Deborah Friedman, Andrew J. Hughes, Anthony McDonald, Peter Callan, Janet Fyfe, Daniel P. O’Brien

PLOS Neglected Tropical Diseases: published February 6, 2015 | https://doi.org/10.1371/journal.pntd.0003503

IL-33/ST2 Correlates with Severity of Haemorrhagic Fever with Renal Syndrome and Regulates the Inflammatory Response in Hantaan Virus-Infected Endothelial Cells

Yusi Zhang, Chunmei Zhang, Ran Zhuang, Ying Ma, Yun Zhang, Jing Yi, Angang Yang, Boquan Jin

PLOS Neglected Tropical Diseases: published February 6, 2015 | https://doi.org/10.1371/journal.pntd.0003514

Chemotherapy of Second Stage Human African Trypanosomiasis: Comparison between the Parenteral Diamidine DB829 and Its Oral Prodrug DB868 in Vervet Monkeys

John K. Thuita, Kristina K. Wolf, Grace A. Murilla, Arlene S. Bridges, David W. Boykin, James N. Mutuku, Qiang Liu, Susan K. Jones, Charles O. Gem, Shelley Ching, Richard R. Tidwell, Michael Z. Wang, Mary F. Paine, Reto Brun

PLOS Neglected Tropical Diseases: published February 5, 2015 | https://doi.org/10.1371/journal.pntd.0003409

Population Structure of the Chagas Disease Vector Triatoma infestans in an Urban Environment

Camilo E. Khatchikian, Erica A. Foley, Corentin M. Barbu, Josephine Hwang, Jenny Ancca-Juárez, Katty Borrini-Mayori, Victor R. Quıspe-Machaca, Cesar Naquira, Dustin Brisson, Michael Z. Levy, The Chagas Disease Working Group in Arequipa

PLOS Neglected Tropical Diseases: published February 3, 2015 | https://doi.org/10.1371/journal.pntd.0003425

Review on Dog Rabies Vaccination Coverage in Africa: A Question of Dog Accessibility or Cost Recovery?

Tariku Jibat, Henk Hogeveen, Monique C. M. Mourits

PLOS Neglected Tropical Diseases: published February 3, 2015 | https://doi.org/10.1371/journal.pntd.0003447

Severity of Old World Cutaneous Leishmaniasis Is Influenced by Previous Exposure to Sandfly Bites in Saudi Arabia

Karina Mondragon-Shem, Waleed S. Al-Salem, Louise Kelly-Hope, Maha Abdeladhim, Mohammed H. Al-Zahrani, Jesus G. Valenzuela, Alvaro Acosta-Serrano

PLOS Neglected Tropical Diseases: published February 3, 2015 | https://doi.org/10.1371/journal.pntd.0003449

Platelet Activating Factor Contributes to Vascular Leak in Acute Dengue Infection

Chandima Jeewandara, Laksiri Gomes, N. Wickramasinghe, Danuta Gutowska-Owsiak, Dominic Waithe, S. A. Paranavitane, N. L. A. Shyamali, Graham S. Ogg, Gathsaurie Neelika Malavige

PLOS Neglected Tropical Diseases: published February 3, 2015 | https://doi.org/10.1371/journal.pntd.0003459

Describing the Breakbone Fever: IDODEN, an Ontology for Dengue Fever

Elvira Mitraka, Pantelis Topalis, Vicky Dritsou, Emmanuel Dialynas, Christos Louis

PLOS Neglected Tropical Diseases: published February 3, 2015 | https://doi.org/10.1371/journal.pntd.0003479

Evidence of Reversible Bradycardia and Arrhythmias Caused by Immunogenic Proteins Secreted by T. cruzi in Isolated Rat Hearts

Héctor O. Rodríguez-Angulo, Jhoan Toro-Mendoza, Juan A. Marques, Juan L. Concepción, Rafael Bonfante-Cabarcas, Yoliver Higuerey, Luz E. Thomas, Leandro Balzano-Nogueira, José R. López, Alfredo Mijares

PLOS Neglected Tropical Diseases: published February 3, 2015 | https://doi.org/10.1371/journal.pntd.0003512

High Prevalence of the Liver Fluke Amphimerus sp. in Domestic Cats and Dogs in an Area for Human Amphimeriasis in Ecuador

Manuel Calvopiña, William Cevallos, Richard Atherton, Matthew Saunders, Alexander Small, Hideo Kumazawa, Hiromu Sugiyama

PLOS Neglected Tropical Diseases: published February 3, 2015 | https://doi.org/10.1371/journal.pntd.0003526

High Prevalence of Schistosoma japonicum and Fasciola gigantica in Bovines from Northern Samar, the Philippines

Catherine A. Gordon, Luz P. Acosta, Geoffrey N. Gobert, Mario Jiz, Remigio M. Olveda, Allen G. Ross, Darren J. Gray, Gail M. Williams, Donald Harn, Yuesheng Li, Donald P. McManus

PLOS Neglected Tropical Diseases: published February 2, 2015 | https://doi.org/10.1371/journal.pntd.0003108

African Adders: Partial Characterization of Snake Venoms from Three Bitis Species of Medical Importance and Their Neutralization by Experimental Equine Antivenoms

Danielle Paixão-Cavalcante, Alexandre K. Kuniyoshi, Fernanda C. V. Portaro, Wilmar Dias da Silva, Denise V. Tambourgi

PLOS Neglected Tropical Diseases: published February 2, 2015 | https://doi.org/10.1371/journal.pntd.0003419

Accuracy of Individual Rapid Tests for Serodiagnosis of Gambiense Sleeping Sickness in West Africa

Vincent Jamonneau, Oumou Camara, Hamidou Ilboudo, Moana Peylhard, Mathurin Koffi, Hassane Sakande, Louis N’Dri, Djénéba Sanou, Emilie Dama, Mamadou Camara, Veerle Lejon

PLOS Neglected Tropical Diseases: published February 2, 2015 | https://doi.org/10.1371/journal.pntd.0003480

Vaccination with Leishmania infantum Acidic Ribosomal P0 but Not with Nucleosomal Histones Proteins Controls Leishmania infantum Infection in Hamsters

Lais Pereira, Melissa Abbehusen, Clarissa Teixeira, Jurema Cunha, Ivan P. Nascimento, Kyioshi Fukutani, Washington dos-Santos, Aldina Barral, Camila Indiani de Oliveira, Manoel Barral-Netto, Manoel Soto, Cláudia Ida Brodskyn

PLOS Neglected Tropical Diseases: published February 2, 2015 | https://doi.org/10.1371/journal.pntd.0003490

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A bite to remember.

Editorials

Viewpoints

From Innovation to Application

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