Cover
Mycobacterium ulcerans infection in an adult common ringtail possum (Pseudocheirus peregrinus).
Buruli ulcer is a skin disease caused by Mycobacterium ulcerans, with endemicity predominantly in sub-Saharan Africa and southeastern Australia. Transmission and the environmental reservoir(s) of the bacterium remain elusive. Investigations have detected Mycobacterium ulcerans DNA in a variety of Australian environmental samples, including faeces of native possums (pictured) with and without clinical evidence of infection. O'Brien et al.
Image Credit: Janet Fyfe and Christina McCowan
Editorial
Aboriginal Populations and Their Neglected Tropical Diseases
PLOS Neglected Tropical Diseases: published January 30, 2014 | https://doi.org/10.1371/journal.pntd.0002286
Viewpoints
TDR: (Back) Making a Difference
PLOS Neglected Tropical Diseases: published January 9, 2014 | https://doi.org/10.1371/journal.pntd.0002531
Symposium
A 21-Year-Old Student with Fever and Profound Jaundice
PLOS Neglected Tropical Diseases: published January 9, 2014 | https://doi.org/10.1371/journal.pntd.0002534
Reviews
Estimating the Burden of Japanese Encephalitis Virus and Other Encephalitides in Countries of the Mekong Region
PLOS Neglected Tropical Diseases: published January 30, 2014 | https://doi.org/10.1371/journal.pntd.0002533
Hard Tick Factors Implicated in Pathogen Transmission
PLOS Neglected Tropical Diseases: published January 30, 2014 | https://doi.org/10.1371/journal.pntd.0002566
Research Articles
A Scoping Review and Prevalence Analysis of Soil-Transmitted Helminth Infections in Honduras
PLOS Neglected Tropical Diseases: published January 23, 2014 | https://doi.org/10.1371/journal.pntd.0002653
The Changing Epidemiology of Murray Valley Encephalitis in Australia: The 2011 Outbreak and a Review of the Literature
PLOS Neglected Tropical Diseases: published January 23, 2014 | https://doi.org/10.1371/journal.pntd.0002656
Strong Association between Serological Status and Probability of Progression to Clinical Visceral Leishmaniasis in Prospective Cohort Studies in India and Nepal
PLOS Neglected Tropical Diseases: published January 23, 2014 | https://doi.org/10.1371/journal.pntd.0002657
L925I Mutation in the Para-Type Sodium Channel Is Associated with Pyrethroid Resistance in Triatoma infestans from the Gran Chaco Region
PLOS Neglected Tropical Diseases: published January 23, 2014 | https://doi.org/10.1371/journal.pntd.0002659
Safety and Efficacy of Single Dose versus Multiple Doses of AmBisome® for Treatment of Visceral Leishmaniasis in Eastern Africa: A Randomised Trial
PLOS Neglected Tropical Diseases: published January 16, 2014 | https://doi.org/10.1371/journal.pntd.0002613
Regional Differences of Leptospirosis in Sri Lanka: Observations from a Flood-Associated Outbreak in 2011
PLOS Neglected Tropical Diseases: published January 16, 2014 | https://doi.org/10.1371/journal.pntd.0002626
Increase in TGF-β Secreting CD4+CD25+ FOXP3+ T Regulatory Cells in Anergic Lepromatous Leprosy Patients
PLOS Neglected Tropical Diseases: published January 16, 2014 | https://doi.org/10.1371/journal.pntd.0002639
Clinical Associations of Human T-Lymphotropic Virus Type 1 Infection in an Indigenous Australian Population
PLOS Neglected Tropical Diseases: published January 16, 2014 | https://doi.org/10.1371/journal.pntd.0002643
Aptamer Based, Non-PCR, Non-Serological Detection of Chagas Disease Biomarkers in Trypanosoma cruzi Infected Mice
PLOS Neglected Tropical Diseases: published January 16, 2014 | https://doi.org/10.1371/journal.pntd.0002650
Heterogeneities in Leishmania infantum Infection: Using Skin Parasite Burdens to Identify Highly Infectious Dogs
PLOS Neglected Tropical Diseases: published January 9, 2014 | https://doi.org/10.1371/journal.pntd.0002583
An Insight into the Transcriptome of the Digestive Tract of the Bloodsucking Bug, Rhodnius prolixus
PLOS Neglected Tropical Diseases: published January 9, 2014 | https://doi.org/10.1371/journal.pntd.0002594
Standardising Visual Control Devices for Tsetse Flies: Central and West African Species Glossina palpalis palpalis
PLOS Neglected Tropical Diseases: published January 9, 2014 | https://doi.org/10.1371/journal.pntd.0002601
Bioassay-Guided Fractionation of Extracts from Codiaeum variegatum against Entamoeba histolytica Discovers Compounds That Modify Expression of Ceramide Biosynthesis Related Genes
PLOS Neglected Tropical Diseases: published January 9, 2014 | https://doi.org/10.1371/journal.pntd.0002607
Orally Active Antischistosomal Early Leads Identified from the Open Access Malaria Box
PLOS Neglected Tropical Diseases: published January 9, 2014 | https://doi.org/10.1371/journal.pntd.0002610
Animal Reservoir, Natural and Socioeconomic Variations and the Transmission of Hemorrhagic Fever with Renal Syndrome in Chenzhou, China, 2006–2010
PLOS Neglected Tropical Diseases: published January 9, 2014 | https://doi.org/10.1371/journal.pntd.0002615
Next Generation Sequencing Reveals Regulation of Distinct Aedes microRNAs during Chikungunya Virus Development
PLOS Neglected Tropical Diseases: published January 9, 2014 | https://doi.org/10.1371/journal.pntd.0002616
Repeated Exposure to Lutzomyia intermedia Sand Fly Saliva Induces Local Expression of Interferon-Inducible Genes Both at the Site of Injection in Mice and in Human Blood
PLOS Neglected Tropical Diseases: published January 9, 2014 | https://doi.org/10.1371/journal.pntd.0002627
Cofactor-Independent Phosphoglycerate Mutase from Nematodes Has Limited Druggability, as Revealed by Two High-Throughput Screens
PLOS Neglected Tropical Diseases: published January 9, 2014 | https://doi.org/10.1371/journal.pntd.0002628
Functional Characterization of Peroxiredoxins from the Human Protozoan Parasite Giardia intestinalis
PLOS Neglected Tropical Diseases: published January 9, 2014 | https://doi.org/10.1371/journal.pntd.0002631
Molecular Evolution of Zika Virus during Its Emergence in the 20th Century
PLOS Neglected Tropical Diseases: published January 9, 2014 | https://doi.org/10.1371/journal.pntd.0002636
Production of CXC and CC Chemokines by Human Antigen-Presenting Cells in Response to Lassa Virus or Closely Related Immunogenic Viruses, and in Cynomolgus Monkeys with Lassa Fever
PLOS Neglected Tropical Diseases: published January 9, 2014 | https://doi.org/10.1371/journal.pntd.0002637
Diagnostic Accuracy of Five Serologic Tests for Strongyloides stercoralis Infection
PLOS Neglected Tropical Diseases: published January 9, 2014 | https://doi.org/10.1371/journal.pntd.0002640
Nodule Worm Infection in Humans and Wild Primates in Uganda: Cryptic Species in a Newly Identified Region of Human Transmission
PLOS Neglected Tropical Diseases: published January 9, 2014 | https://doi.org/10.1371/journal.pntd.0002641
Predicting the Impact of Vaccination on the Transmission Dynamics of Typhoid in South Asia: A Mathematical Modeling Study
PLOS Neglected Tropical Diseases: published January 9, 2014 | https://doi.org/10.1371/journal.pntd.0002642
Characterization of a Gene Family Encoding SEA (Sea-urchin Sperm Protein, Enterokinase and Agrin)-Domain Proteins with Lectin-Like and Heme-Binding Properties from Schistosoma japonicum
PLOS Neglected Tropical Diseases: published January 9, 2014 | https://doi.org/10.1371/journal.pntd.0002644
LmaPA2G4, a Homolog of Human Ebp1, Is an Essential Gene and Inhibits Cell Proliferation in L. major
PLOS Neglected Tropical Diseases: published January 9, 2014 | https://doi.org/10.1371/journal.pntd.0002646
Molecular Epidemiology of Crimean-Congo Hemorrhagic Fever Virus in Kosovo
PLOS Neglected Tropical Diseases: published January 9, 2014 | https://doi.org/10.1371/journal.pntd.0002647
Risk Factors for Visceral Leishmaniasis Relapse in Immunocompetent Patients following Treatment with 20 mg/kg Liposomal Amphotericin B (Ambisome) in Bihar, India
PLOS Neglected Tropical Diseases: published January 2, 2014 | https://doi.org/10.1371/journal.pntd.0002536
Related Articles
Recombinant Antigens from Phlebotomus perniciosus Saliva as Markers of Canine Exposure to Visceral Leishmaniases Vector
PLOS Neglected Tropical Diseases: published January 2, 2014 | https://doi.org/10.1371/journal.pntd.0002597
Five-Year Field Results and Long-Term Effectiveness of 20 mg/kg Liposomal Amphotericin B (Ambisome) for Visceral Leishmaniasis in Bihar, India
PLOS Neglected Tropical Diseases: published January 2, 2014 | https://doi.org/10.1371/journal.pntd.0002603
Related Articles
Analysis of the Vaccine Potential of Plasmid DNA Encoding Nine Mycolactone Polyketide Synthase Domains in Mycobacterium ulcerans Infected Mice
PLOS Neglected Tropical Diseases: published January 2, 2014 | https://doi.org/10.1371/journal.pntd.0002604
Household-Level Expenditure on Protective Measures Against Mosquitoes on the Island of La Réunion, France
PLOS Neglected Tropical Diseases: published January 2, 2014 | https://doi.org/10.1371/journal.pntd.0002609
Post Kala-Azar Dermal Leishmaniasis following Treatment with 20 mg/kg Liposomal Amphotericin B (Ambisome) for Primary Visceral Leishmaniasis in Bihar, India
PLOS Neglected Tropical Diseases: published January 2, 2014 | https://doi.org/10.1371/journal.pntd.0002611
Related Articles
Clinical Features and Risk Factors of Oedematous Mycobacterium ulcerans Lesions in an Australian Population: Beware Cellulitis in an Endemic Area
PLOS Neglected Tropical Diseases: published January 2, 2014 | https://doi.org/10.1371/journal.pntd.0002612
Phytol, a Diterpene Alcohol from Chlorophyll, as a Drug against Neglected Tropical Disease Schistosomiasis Mansoni
PLOS Neglected Tropical Diseases: published January 2, 2014 | https://doi.org/10.1371/journal.pntd.0002617
Accelerated Detection of Mycolactone Production and Response to Antibiotic Treatment in a Mouse Model of Mycobacterium ulcerans Disease
PLOS Neglected Tropical Diseases: published January 2, 2014 | https://doi.org/10.1371/journal.pntd.0002618
Reinfection of Dogs with Fish-Borne Zoonotic Trematodes in Northern Vietnam following a Single Treatment with Praziquantel
PLOS Neglected Tropical Diseases: published January 2, 2014 | https://doi.org/10.1371/journal.pntd.0002625
EmTIP, a T-Cell Immunomodulatory Protein Secreted by the Tapeworm Echinococcus multilocularis Is Important for Early Metacestode Development
PLOS Neglected Tropical Diseases: published January 2, 2014 | https://doi.org/10.1371/journal.pntd.0002632
The Trypanosoma cruzi Satellite DNA OligoC-TesT and Trypanosoma cruzi Kinetoplast DNA OligoC-TesT for Diagnosis of Chagas Disease: A Multi-cohort Comparative Evaluation Study
PLOS Neglected Tropical Diseases: published January 2, 2014 | https://doi.org/10.1371/journal.pntd.0002633
The Burden of Parasitic Zoonoses in Nepal: A Systematic Review
PLOS Neglected Tropical Diseases: published January 2, 2014 | https://doi.org/10.1371/journal.pntd.0002634
Scrub Typhus Is an Under-recognized Cause of Acute Febrile Illness with Acute Kidney Injury in India
PLOS Neglected Tropical Diseases: published January 30, 2014 | https://doi.org/10.1371/journal.pntd.0002605
Risk Factors for Disseminated Histoplasmosis in a Cohort of HIV-Infected Patients in French Guiana
PLOS Neglected Tropical Diseases: published January 30, 2014 | https://doi.org/10.1371/journal.pntd.0002638
Related Articles
Assembly of the Genome of the Disease Vector Aedes aegypti onto a Genetic Linkage Map Allows Mapping of Genes Affecting Disease Transmission
PLOS Neglected Tropical Diseases: published January 30, 2014 | https://doi.org/10.1371/journal.pntd.0002652
Parasite-Antigen Driven Expansion of IL-5− and IL-5+ Th2 Human Subpopulations in Lymphatic Filariasis and Their Differential Dependence on IL-10 and TGFβ
PLOS Neglected Tropical Diseases: published January 30, 2014 | https://doi.org/10.1371/journal.pntd.0002658
First Detection of Mycobacterium ulcerans DNA in Environmental Samples from South America
PLOS Neglected Tropical Diseases: published January 30, 2014 | https://doi.org/10.1371/journal.pntd.0002660
Leptospira Interrogans Induces Fibrosis in the Mouse Kidney through Inos-Dependent, TLR- and NLR-Independent Signaling Pathways
PLOS Neglected Tropical Diseases: published January 30, 2014 | https://doi.org/10.1371/journal.pntd.0002664
Related Articles
Clinical, Microbiological and Pathological Findings of Mycobacterium ulcerans Infection in Three Australian Possum Species
PLOS Neglected Tropical Diseases: published January 30, 2014 | https://doi.org/10.1371/journal.pntd.0002666
Potential Wildlife Sentinels for Monitoring the Endemic Spread of Human Buruli Ulcer in South-East Australia
PLOS Neglected Tropical Diseases: published January 30, 2014 | https://doi.org/10.1371/journal.pntd.0002668
CRISPR Is an Optimal Target for the Design of Specific PCR Assays for Salmonella enterica Serotypes Typhi and Paratyphi A
PLOS Neglected Tropical Diseases: published January 30, 2014 | https://doi.org/10.1371/journal.pntd.0002671
Leptospira interrogans Binds to Cadherins
PLOS Neglected Tropical Diseases: published January 30, 2014 | https://doi.org/10.1371/journal.pntd.0002672
A Cytoplasmic New Catalytic Subunit of Calcineurin in Trypanosoma cruzi and Its Molecular and Functional Characterization
PLOS Neglected Tropical Diseases: published January 30, 2014 | https://doi.org/10.1371/journal.pntd.0002676