Cover
Enterotoxigenic Escherichia coli (ETEC) engaging the apical surface of intestinal epithelial cells.
The enterotoxigenic E. coli (ETEC) are a common cause of diarrheal illness in developing countries where these organisms cause hundreds of thousands of deaths annually. Antigenic variability among known ETEC vaccine targets has prompted searches for additional conserved antigens that could be used to prevent ETEC infections. In this issue, Harris et al. explore the use of a highly conserved class of surface proteins known as autotransporters as potential ETEC vaccine constituents. This composite image shows host cell membrane (green), cellular actin (red), and nucleic acid (bacteria and cellular nuclei, blue).
Image Credit: James M. Fleckenstein, Thomas Wong, Michael Whitt (University of Tennessee Health Sciences Center)
Editorial
An Interfaith Dialogue on the Neglected Tropical Diseases
PLOS Neglected Tropical Diseases: published December 20, 2011 | https://doi.org/10.1371/journal.pntd.0001240
Photo Quiz
Generalized Serpiginous Eruption during Immunosuppressive Treatment for Leprosy Reactive Neuritis
PLOS Neglected Tropical Diseases: published December 27, 2011 | https://doi.org/10.1371/journal.pntd.0001357
Reviews
The Use of Artemether-Lumefantrine for the Treatment of Uncomplicated Plasmodium vivax Malaria
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Individuals with Le(a+b−) Blood Group Have Increased Susceptibility to Symptomatic Vibrio cholerae O1 Infection
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Dengue Virus Type 4 Phylogenetics in Brazil 2011: Looking beyond the Veil
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In Vitro and In Vivo Efficacy of Monepantel (AAD 1566) against Laboratory Models of Human Intestinal Nematode Infections
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Genetic Engineering of Trypanosoma (Dutonella) vivax and In Vitro Differentiation under Axenic Conditions
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