Most organisms segregate their duplicated genome copies on bipolar microtubular spindles. E. histolytica nuclei often accumulate multiple copies of the genome. This micrograph shows multi-polar microtubular spindles where genome segregation likely occurs in E. histolytica cells (see Mukherjee et al., doi:10.1371/journal.pntd.0000409).
Image Credit: Shubhra Majumder, Bose Institute
Editorial
One World Health: Neglected Tropical Diseases in a Flat World
PLOS Neglected Tropical Diseases: published April 28, 2009 | https://doi.org/10.1371/journal.pntd.0000405
Viewpoints
Conducting Research in Disease Outbreaks
PLOS Neglected Tropical Diseases: published April 28, 2009 | https://doi.org/10.1371/journal.pntd.0000335
Introduction of Dengue Virus 4 (DENV-4) Genotype I into Brazil from Asia?
PLOS Neglected Tropical Diseases: published April 28, 2009 | https://doi.org/10.1371/journal.pntd.0000390
Review
Use of Mapping and Spatial and Space-Time Modeling Approaches in Operational Control of Aedes aegypti and Dengue
PLOS Neglected Tropical Diseases: published April 28, 2009 | https://doi.org/10.1371/journal.pntd.0000411
Research Articles
Development and Evaluation of Two Simple, Rapid Immunochromatographic Tests for the Detection of Yersinia pestis Antibodies in Humans and Reservoirs
PLOS Neglected Tropical Diseases: published April 28, 2009 | https://doi.org/10.1371/journal.pntd.0000421
Dengue Virus Serotype 2 from a Sylvatic Lineage Isolated from a Patient with Dengue Hemorrhagic Fever
PLOS Neglected Tropical Diseases: published April 28, 2009 | https://doi.org/10.1371/journal.pntd.0000423
Echinococcus granulosus Infection and Options for Control of Cystic Echinococcosis in Tibetan Communities of Western Sichuan Province, China
PLOS Neglected Tropical Diseases: published April 28, 2009 | https://doi.org/10.1371/journal.pntd.0000426
Effects of a Five-Year Citywide Intervention Program To Control Aedes aegypti and Prevent Dengue Outbreaks in Northern Argentina
PLOS Neglected Tropical Diseases: published April 28, 2009 | https://doi.org/10.1371/journal.pntd.0000427
Marriage, Sex, and Hydrocele: An Ethnographic Study on the Effect of Filarial Hydrocele on Conjugal Life and Marriageability from Orissa, India
PLOS Neglected Tropical Diseases: published April 21, 2009 | https://doi.org/10.1371/journal.pntd.0000414
A Kernel for Open Source Drug Discovery in Tropical Diseases
PLOS Neglected Tropical Diseases: published April 21, 2009 | https://doi.org/10.1371/journal.pntd.0000418
Accurate Real-Time PCR Strategy for Monitoring Bloodstream Parasitic Loads in Chagas Disease Patients
PLOS Neglected Tropical Diseases: published April 21, 2009 | https://doi.org/10.1371/journal.pntd.0000419
Filarial Lymphedema Is Characterized by Antigen-Specific Th1 and Th17 Proinflammatory Responses and a Lack of Regulatory T Cells
PLOS Neglected Tropical Diseases: published April 21, 2009 | https://doi.org/10.1371/journal.pntd.0000420
Diagnosing Schistosomiasis by Detection of Cell-Free Parasite DNA in Human Plasma
PLOS Neglected Tropical Diseases: published April 21, 2009 | https://doi.org/10.1371/journal.pntd.0000422
Gene Flow, Subspecies Composition, and Dengue Virus-2 Susceptibility among Aedes aegypti Collections in Senegal
PLOS Neglected Tropical Diseases: published April 14, 2009 | https://doi.org/10.1371/journal.pntd.0000408
Proteomic Comparison of Entamoeba histolytica and Entamoeba dispar and the Role of E. histolytica Alcohol Dehydrogenase 3 in Virulence
PLOS Neglected Tropical Diseases: published April 14, 2009 | https://doi.org/10.1371/journal.pntd.0000415
Optimization of Control Strategies for Non-Domiciliated Triatoma dimidiata, Chagas Disease Vector in the Yucatán Peninsula, Mexico
PLOS Neglected Tropical Diseases: published April 14, 2009 | https://doi.org/10.1371/journal.pntd.0000416
Phenotypic and Functional Characterization of Human Memory T Cell Responses to Burkholderia pseudomallei
PLOS Neglected Tropical Diseases: published April 7, 2009 | https://doi.org/10.1371/journal.pntd.0000407
Inter-Cellular Variation in DNA Content of Entamoeba histolytica Originates from Temporal and Spatial Uncoupling of Cytokinesis from the Nuclear Cycle
PLOS Neglected Tropical Diseases: published April 7, 2009 | https://doi.org/10.1371/journal.pntd.0000409
Brugia malayi Excreted/Secreted Proteins at the Host/Parasite Interface: Stage- and Gender-Specific Proteomic Profiling
PLOS Neglected Tropical Diseases: published April 7, 2009 | https://doi.org/10.1371/journal.pntd.0000410