Genotypic Diversity Is Associated with Clinical Outcome and Phenotype in Cryptococcal Meningitis across Southern Africa

• Mathew A. Beale,

  Affiliations Institute of Infection and Immunity, St. George’s University London, London, United Kingdom, Department of Infectious Disease Epidemiology, Imperial College School of Public Health, London, United Kingdom

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• Wilber Sabiiti,

  Affiliations Institute of Infection and Immunity, St. George’s University London, London, United Kingdom, School of Medicine University of St. Andrews, St. Andrews, United Kingdom

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• Emma J. Robertson,

  Affiliation Institute of Infection and Immunity, St. George’s University London, London, United Kingdom

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• Karen M. Fuentes-Cabrejo,

  Affiliation Institute of Infection and Immunity, St. George’s University London, London, United Kingdom

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• Simon J. O’Hanlon,

  Affiliation Department of Infectious Disease Epidemiology, Imperial College School of Public Health, London, United Kingdom

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• Joseph N. Jarvis,

  Affiliations Botswana-UPenn Partnership, Gaborone, Botswana, Division of Infectious Diseases, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America, Department of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom

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• Angela Loyse,

  Affiliation Institute of Infection and Immunity, St. George’s University London, London, United Kingdom

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• Graeme Meintjes,

  Affiliations Division of Infectious Diseases and HIV Medicine, Department of Medicine, University of Cape Town, Cape Town, South Africa, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa

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• Thomas S. Harrison,

  Affiliation Institute of Infection and Immunity, St. George’s University London, London, United Kingdom

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• Robin C. May,

  Affiliations Institute of Microbiology and Infection and the School of Biosciences, University of Birmingham, Birmingham, United Kingdom, National Institute for Health Research (NIHR) Surgical Reconstruction and Microbiology Research Centre, University Hospitals of Birmingham National Health Service (NHS) Foundation Trust, Queen Elizabeth Hospital Birmingham, Birmingham, United Kingdom

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• Matthew C. Fisher ,

  * E-mail: matthew.fisher@imperial.ac.uk (MCF); tbicanic@sgul.ac.uk (TB)

  ¶‡ These authors are joint senior authors on this work.

  Affiliation Department of Infectious Disease Epidemiology, Imperial College School of Public Health, London, United Kingdom

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• Tihana Bicanic

  * E-mail: matthew.fisher@imperial.ac.uk (MCF); tbicanic@sgul.ac.uk (TB)

  ¶‡ These authors are joint senior authors on this work.

  Affiliation Institute of Infection and Immunity, St. George’s University London, London, United Kingdom

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