Immunization with Hexon Modified Adenoviral Vectors Integrated with gp83 Epitope Provides Protection against Trypanosoma cruzi Infection

Anitra L. Farrow; Girish Rachakonda; Linlin Gu; Valentina Krendelchtchikova; Pius N. Nde; Siddharth Pratap; Maria F. Lima; Fernando Villalta; Qiana L. Matthews

doi:10.1371/journal.pntd.0003089

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Open Access

Peer-reviewed

Research Article

Immunization with Hexon Modified Adenoviral Vectors Integrated with gp83 Epitope Provides Protection against Trypanosoma cruzi Infection

Anitra L. Farrow ,

Contributed equally to this work with: Anitra L. Farrow, Girish Rachakonda

Affiliation Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
⨯
Girish Rachakonda ,

Contributed equally to this work with: Anitra L. Farrow, Girish Rachakonda

Affiliation Department of Microbiology and Immunology, School of Medicine, Meharry Medical College, Nashville, Tennessee, United States of America
⨯
Linlin Gu,

Affiliation Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
⨯
Valentina Krendelchtchikova,

Affiliation Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
⨯
Pius N. Nde,

Affiliation Department of Microbiology and Immunology, School of Medicine, Meharry Medical College, Nashville, Tennessee, United States of America
⨯
Siddharth Pratap,

Affiliation Department of Microbiology and Immunology, School of Medicine, Meharry Medical College, Nashville, Tennessee, United States of America
⨯
Maria F. Lima,

Affiliation Department of Microbiology and Immunology, School of Medicine, Meharry Medical College, Nashville, Tennessee, United States of America
⨯
Fernando Villalta ,

* E-mail: fvillalta@mmc.edu (FV); qlm@uab.edu (QLM)

Affiliation Department of Microbiology and Immunology, School of Medicine, Meharry Medical College, Nashville, Tennessee, United States of America
⨯
Qiana L. Matthews

* E-mail: fvillalta@mmc.edu (FV); qlm@uab.edu (QLM)

Affiliations Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, Alabama, United States of America, Center for AIDS Research, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
⨯

Immunization with Hexon Modified Adenoviral Vectors Integrated with gp83 Epitope Provides Protection against Trypanosoma cruzi Infection

Anitra L. Farrow,
Girish Rachakonda,
Linlin Gu,
Valentina Krendelchtchikova,
Pius N. Nde,
Siddharth Pratap,
Maria F. Lima,
Fernando Villalta,
Qiana L. Matthews

Published: August 21, 2014
https://doi.org/10.1371/journal.pntd.0003089

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