Sulfated Polysaccharide, Curdlan Sulfate, Efficiently Prevents Entry/Fusion and Restricts Antibody-Dependent Enhancement of Dengue Virus Infection In Vitro: A Possible Candidate for Clinical Application

• Koji Ichiyama ,

  Contributed equally to this work with: Koji Ichiyama, Sindhoora Bhargavi Gopala Reddy

  Affiliations Translational ID Lab, Department of Microbiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore, Department of Human Sciences, Musashino University, Tokyo, Japan

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• Sindhoora Bhargavi Gopala Reddy ,

  Contributed equally to this work with: Koji Ichiyama, Sindhoora Bhargavi Gopala Reddy

  Affiliations Translational ID Lab, Department of Microbiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore, Department of Biotechnology, Sri Jayachamarajendra College of Engineering, Mysore, Karnataka, India

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• Li Feng Zhang,

  Affiliation Translational ID Lab, Department of Microbiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore

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• Wei Xin Chin,

  Affiliation Translational ID Lab, Department of Microbiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore

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• Tegshi Muschin,

  Affiliation Department of Bio and Environmental Chemistry, Kitami Institute of Technology, Kitami, Japan

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• Lars Heinig,

  Affiliation Translational ID Lab, Department of Microbiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore

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• Youichi Suzuki,

  Affiliation Translational ID Lab, Department of Microbiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore

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• Haraprasad Nanjundappa,

  Affiliation Department of Biotechnology, Sri Jayachamarajendra College of Engineering, Mysore, Karnataka, India

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• Yoshiyuki Yoshinaka,

  Affiliation Department of Molecular Virology, Tokyo Medical and Dental University, Tokyo, Japan

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• Akihide Ryo,

  Affiliation Department of Microbiology, Yokohama City University School of Medicine, Yokohama, Japan

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• Nobuo Nomura,

  Affiliation Department of Human Sciences, Musashino University, Tokyo, Japan

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• Eng Eong Ooi,

  Affiliation Program in Emerging Infectious Diseases, Duke-NUS Graduate Medical School, Singapore, Singapore

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• Subhash G. Vasudevan,

  Affiliation Program in Emerging Infectious Diseases, Duke-NUS Graduate Medical School, Singapore, Singapore

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• Takashi Yoshida,

  Affiliation Department of Bio and Environmental Chemistry, Kitami Institute of Technology, Kitami, Japan

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• Naoki Yamamoto

  * E-mail: micny@nus.edu.sg

  Affiliation Translational ID Lab, Department of Microbiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore

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