Case-area targeted interventions (CATIs) – whereby teams deliver a mixture of health and water, sanitation, and hygiene (WASH) interventions to cholera case households and neighboring households within a pre-determined radius – have become an increasingly common strategy to respond to cholera outbreaks. In this issue, Jennifer OKeeffe and colleagues prospectively study the impact of CATIs in Northeast Nigeria during the 2021 cholera outbreak to better understand how to successfully deploy and scale up CATIs as a core response to future outbreaks.
Image Credit: Kelly/Pexels
Research Articles
Physical activity across midlife and health-related quality of life in Australian women: A target trial emulation using a longitudinal cohort
PLOS Medicine: published May 2, 2024 | https://doi.org/10.1371/journal.pmed.1004384
Impact and cost-effectiveness of the 6-month BPaLM regimen for rifampicin-resistant tuberculosis in Moldova: A mathematical modeling analysis
PLOS Medicine: published May 3, 2024 | https://doi.org/10.1371/journal.pmed.1004401
Prolonged mass azithromycin distributions and macrolide resistance determinants among preschool children in Niger: A sub-study of a cluster-randomized trial (MORDOR)
PLOS Medicine: published May 6, 2024 | https://doi.org/10.1371/journal.pmed.1004386
Sexual behaviour and incidence of sexually transmitted infections among men who have sex with men (MSM) using daily and event-driven pre-exposure prophylaxis (PrEP): Four-year follow-up of the Amsterdam PrEP (AMPrEP) demonstration project cohort
PLOS Medicine: published May 8, 2024 | https://doi.org/10.1371/journal.pmed.1004328
Measuring protective efficacy and quantifying the impact of drug resistance: A novel malaria chemoprevention trial design and methodology
PLOS Medicine: published May 9, 2024 | https://doi.org/10.1371/journal.pmed.1004376
The cyclical cascade of HIV care: Temporal care engagement trends within a population-wide cohort
PLOS Medicine: published May 10, 2024 | https://doi.org/10.1371/journal.pmed.1004407
Case-area targeted interventions during a large-scale cholera epidemic: A prospective cohort study in Northeast Nigeria
PLOS Medicine: published May 10, 2024 | https://doi.org/10.1371/journal.pmed.1004404
Deworming and micronutrient status by community open defecation prevalence: An observational study using nationally representative data from India, 2016–2018
PLOS Medicine: published May 10, 2024 | https://doi.org/10.1371/journal.pmed.1004402
Predicted impact of banning nonessential, energy-dense food and beverages in schools in Mexico: A microsimulation study
PLOS Medicine: published May 10, 2024 | https://doi.org/10.1371/journal.pmed.1004394
Cetuximab plus FOLFOXIRI versus cetuximab plus FOLFOX as conversion regimen in RAS/BRAF wild-type patients with initially unresectable colorectal liver metastases (TRICE trial): A randomized controlled trial
PLOS Medicine: published May 10, 2024 | https://doi.org/10.1371/journal.pmed.1004389
User-defined outcomes of the Danish cardiovascular screening (DANCAVAS) trial: A post hoc analyses of a population-based, randomised controlled trial
PLOS Medicine: published May 13, 2024 | https://doi.org/10.1371/journal.pmed.1004403
Global, regional, and national burden of heatwave-related mortality from 1990 to 2019: A three-stage modelling study
PLOS Medicine: published May 14, 2024 | https://doi.org/10.1371/journal.pmed.1004364
Radiation enhancement using focussed ultrasound-stimulated microbubbles for breast cancer: A Phase 1 clinical trial
PLOS Medicine: published May 17, 2024 | https://doi.org/10.1371/journal.pmed.1004408
Aetiology of vaginal discharge, urethral discharge, and genital ulcer in sub-Saharan Africa: A systematic review and meta-regression
PLOS Medicine: published May 20, 2024 | https://doi.org/10.1371/journal.pmed.1004385
Barriers to engagement in the care cascade for tuberculosis disease in India: A systematic review of quantitative studies
PLOS Medicine: published May 28, 2024 | https://doi.org/10.1371/journal.pmed.1004409
Factors influencing the participation of pregnant and lactating women in clinical trials: A mixed-methods systematic review
PLOS Medicine: published May 30, 2024 | https://doi.org/10.1371/journal.pmed.1004405
Incidence of self-reported tuberculosis treatment with community-wide universal testing and treatment for HIV and tuberculosis screening in Zambia and South Africa: A planned analysis of the HPTN 071 (PopART) cluster-randomised trial
PLOS Medicine: published May 31, 2024 | https://doi.org/10.1371/journal.pmed.1004393