Diabetes already affects more than 400 million adults globally, and this burden is projected to increase to more than 600 million adults by the year 2040. Non-diabetic hyperglycaemia, also known as pre-diabetes, refers to increased blood glucose levels that are not high enough to be classed as diabetic, and individuals with pre-diabetes are an important target group for prevention of type 2 diabetes. In this issue, Rathi Ravindrarajah et al present findings from the NHS Healthier You Diabetes Programme, which included data from over 700,000 adults with pre-diabetes, 100,000 of whom were referred to the programme and offered healthy lifestyle advice to reduce risk of progression to type 2 diabetes. Multivariable survival analyses suggest that the risk was 20% lower in those referred to the programme, supporting the case for a rapid rollout of the programme across England as well as the introduction of similar programmes elsewhere in the UK.
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Research Articles
Neonatal and maternal adverse outcomes and exposure to nonsteroidal anti-inflammatory drugs during early pregnancy in South Korea: A nationwide cohort study
PLOS Medicine: published February 27, 2023 | https://doi.org/10.1371/journal.pmed.1004183
Evaluation of conditional cash transfers and mHealth audio messaging in reduction of risk factors for childhood malnutrition in internally displaced persons camps in Somalia: A 2 × 2 factorial cluster-randomised controlled trial
PLOS Medicine: published February 27, 2023 | https://doi.org/10.1371/journal.pmed.1004180
Referral to the NHS Diabetes Prevention Programme and conversion from nondiabetic hyperglycaemia to type 2 diabetes mellitus in England: A matched cohort analysis
PLOS Medicine: published February 27, 2023 | https://doi.org/10.1371/journal.pmed.1004177
Comparison of new psychiatric diagnoses among Finnish children and adolescents before and during the COVID-19 pandemic: A nationwide register-based study
PLOS Medicine: published February 27, 2023 | https://doi.org/10.1371/journal.pmed.1004072
Causes of death in children with congenital Zika syndrome in Brazil, 2015 to 2018: A nationwide record linkage study
PLOS Medicine: published February 24, 2023 | https://doi.org/10.1371/journal.pmed.1004181
Long-term risk of inflammatory bowel disease after endoscopic biopsy with normal mucosa: A population-based, sibling-controlled cohort study in Sweden
PLOS Medicine: published February 23, 2023 | https://doi.org/10.1371/journal.pmed.1004185
Health worker compliance with severe malaria treatment guidelines in the context of implementing pre-referral rectal artesunate in the Democratic Republic of the Congo, Nigeria, and Uganda: An operational study
PLOS Medicine: published February 21, 2023 | https://doi.org/10.1371/journal.pmed.1004189
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PLOS Medicine: published February 21, 2023 | https://doi.org/10.1371/journal.pmed.1004127
High PrEP uptake and objective longitudinal adherence among HIV-exposed women with personal or partner plans for pregnancy in rural Uganda: A cohort study
PLOS Medicine: published February 16, 2023 | https://doi.org/10.1371/journal.pmed.1004088
Suicidal ideation following self-reported COVID-19-like symptoms or serology-confirmed SARS-CoV-2 infection in France: A propensity score weighted analysis from a cohort study
PLOS Medicine: published February 14, 2023 | https://doi.org/10.1371/journal.pmed.1004171
Fortified balanced energy–protein supplementation during pregnancy and lactation and infant growth in rural Burkina Faso: A 2 × 2 factorial individually randomized controlled trial
PLOS Medicine: published February 6, 2023 | https://doi.org/10.1371/journal.pmed.1004186
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