Depression presents a major cause of disability globally, but there is a paucity of data available from low- and middle-income countries in the context of HIV. This research gap is important to address given that there were 38.4 million people living with HIV worldwide in 2021 according to statistics from the World Health Organisation. Perhaps more sobering still, almost half of those living with HIV are women of childbearing age, and perinatal women living with HIV have a greater risk of depression compared to other women. In a commentary in this issue of PLOS Medicine, Mark Tomlinson and Mary Jane Rotheram-Borus discuss a new peer-facilitated psychological group intervention for perinatal women living with HIV and receiving antiretroviral therapy. They also provide detailed insight into key areas of design and evaluation with a view to driving forward the field of perinatal mental health interventions.
Image Credit: Annie Spratt, Unsplash
Perspective
When less is more: The way forward for mental health interventions during the perinatal period
PLOS Medicine: published December 13, 2022 | https://doi.org/10.1371/journal.pmed.1004138
Research Articles
Associations of genetically predicted fatty acid levels across the phenome: A mendelian randomisation study
PLOS Medicine: published December 29, 2022 | https://doi.org/10.1371/journal.pmed.1004141
The effect of population-based blood pressure screening on long-term cardiometabolic morbidity and mortality in Germany: A regression discontinuity analysis
PLOS Medicine: published December 27, 2022 | https://doi.org/10.1371/journal.pmed.1004151
Infection and transmission risks of COVID-19 in schools and their contribution to population infections in Germany: A retrospective observational study using nationwide and regional health and education agency notification data
PLOS Medicine: published December 20, 2022 | https://doi.org/10.1371/journal.pmed.1003913
Estimated economic burden of genital herpes and HIV attributable to herpes simplex virus type 2 infections in 90 low- and middle-income countries: A modeling study
PLOS Medicine: published December 15, 2022 | https://doi.org/10.1371/journal.pmed.1003938
Understanding ethnic inequalities in mental healthcare in the UK: A meta-ethnography
PLOS Medicine: published December 13, 2022 | https://doi.org/10.1371/journal.pmed.1004139
A peer-facilitated psychological group intervention for perinatal women living with HIV and depression in Tanzania-Healthy Options: A cluster-randomized controlled trial
PLOS Medicine: published December 13, 2022 | https://doi.org/10.1371/journal.pmed.1004112
Association between antidementia medication use and mortality in people diagnosed with dementia with Lewy bodies in the UK: A retrospective cohort study
PLOS Medicine: published December 6, 2022 | https://doi.org/10.1371/journal.pmed.1004124
Addressing the diagnostic gap in hypertension through possible interventions and scale-up: A microsimulation study
PLOS Medicine: published December 6, 2022 | https://doi.org/10.1371/journal.pmed.1004111
Care cascades for hypertension and diabetes: Cross-sectional evaluation of rural districts in Tanzania
PLOS Medicine: published December 5, 2022 | https://doi.org/10.1371/journal.pmed.1004140
Association between primary or booster COVID-19 mRNA vaccination and Omicron lineage BA.1 SARS-CoV-2 infection in people with a prior SARS-CoV-2 infection: A test-negative case–control analysis
PLOS Medicine: published December 1, 2022 | https://doi.org/10.1371/journal.pmed.1004136
Discontinuation and tapering of prescribed opioids and risk of overdose among people on long-term opioid therapy for pain with and without opioid use disorder in British Columbia, Canada: A retrospective cohort study
PLOS Medicine: published December 1, 2022 | https://doi.org/10.1371/journal.pmed.1004123