With a yet undefined proportion of individuals suffering from long-term health problems following an acute COVID-19 infection, various studies have investigated post-acute COVID syndrome with a view to characterising the associated health sequalae. Despite this growing literature, the evidence in children and adolescents remains limited. In this issue of PLOS Medicine, Martin Roessler and colleagues present findings from a matched cohort study, including data from more than 145,000 adults and approximately 12,000 children and adolescents. They observed increased rates of newly diagnosed physical and mental health problems in individuals with a prior PCR confirmed diagnoses of COVID-19, compared to the control group, and these differed according to age. While children and adolescents appeared to be less affected than adults, these findings suggest that a broad spectrum of health problems may be relevant depending on age group.
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Perspective
Infection, immunity, and surveillance of COVID-19
PLOS Medicine: published November 10, 2022 | https://doi.org/10.1371/journal.pmed.1004132
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PLOS Medicine: published November 9, 2022 | https://doi.org/10.1371/journal.pmed.1004126
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