Preprints are scientific papers that have been made available for general scrutiny prior to or alongside formal peer review and publication. Although preprinting has been a common mechanism for scientific critique and debate in some disciplines for many years, broader use and acceptance has been held back by concerns about the potential for loss of scientific priority and perceived risks of propagating misinformation. However, preprints hold great promise for accelerating scientific progress and discovery, and this potential has been realized during the COVID-19 pandemic for preprints in health and medical research. In an Editorial, Marcel LaFlamme and Raffaella Bosurgi discuss PLOS Medicine's evolving policy on preprint deposition.
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Editorial
Facilitating preprint sharing in the health sciences
PLOS Medicine: published June 21, 2022 | https://doi.org/10.1371/journal.pmed.1004051
Perspectives
Detecting fetal growth restriction with customised assessment: Is the jury still out?
PLOS Medicine: published June 21, 2022 | https://doi.org/10.1371/journal.pmed.1004028
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Addressing the impacts of COVID-19 on refugee health
PLOS Medicine: published June 27, 2022 | https://doi.org/10.1371/journal.pmed.1004050
Policy Forum
Cancer systems epidemiology: Overcoming misconceptions and integrating systems approaches into cancer research
PLOS Medicine: published June 17, 2022 | https://doi.org/10.1371/journal.pmed.1004027
Research Articles
Exposure to road traffic noise and cognitive development in schoolchildren in Barcelona, Spain: A population-based cohort study
PLOS Medicine: published June 2, 2022 | https://doi.org/10.1371/journal.pmed.1004001
Incidence of nonvalvular atrial fibrillation and oral anticoagulant prescribing in England, 2009 to 2019: A cohort study
PLOS Medicine: published June 7, 2022 | https://doi.org/10.1371/journal.pmed.1004003
Radiotherapy to the prostate for men with metastatic prostate cancer in the UK and Switzerland: Long-term results from the STAMPEDE randomised controlled trial
PLOS Medicine: published June 7, 2022 | https://doi.org/10.1371/journal.pmed.1003998
Scaling up target regimens for tuberculosis preventive treatment in Brazil and South Africa: An analysis of costs and cost-effectiveness
PLOS Medicine: published June 13, 2022 | https://doi.org/10.1371/journal.pmed.1004032
Integration of a multicomponent intervention for hypertension into primary healthcare services in Singapore—A cluster randomized controlled trial
PLOS Medicine: published June 13, 2022 | https://doi.org/10.1371/journal.pmed.1004026
Analysis of mortality metrics associated with a comprehensive range of disorders in Denmark, 2000 to 2018: A population-based cohort study
PLOS Medicine: published June 16, 2022 | https://doi.org/10.1371/journal.pmed.1004023
School racial segregation and long-term cardiovascular health among Black adults in the US: A quasi-experimental study
PLOS Medicine: published June 21, 2022 | https://doi.org/10.1371/journal.pmed.1004031
Safety evaluation of the single-dose Ad26.COV2.S vaccine among healthcare workers in the Sisonke study in South Africa: A phase 3b implementation trial
PLOS Medicine: published June 21, 2022 | https://doi.org/10.1371/journal.pmed.1004024
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Adverse events of special interest and mortality following vaccination with mRNA (BNT162b2) and inactivated (CoronaVac) SARS-CoV-2 vaccines in Hong Kong: A retrospective study
PLOS Medicine: published June 21, 2022 | https://doi.org/10.1371/journal.pmed.1004018
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Evaluation of the Growth Assessment Protocol (GAP) for antenatal detection of small for gestational age: The DESiGN cluster randomised trial
PLOS Medicine: published June 21, 2022 | https://doi.org/10.1371/journal.pmed.1004004
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Physiologically based cord clamping for infants ≥32+0 weeks gestation: A randomised clinical trial and reference percentiles for heart rate and oxygen saturation for infants ≥35+0 weeks gestation
PLOS Medicine: published June 23, 2022 | https://doi.org/10.1371/journal.pmed.1004029
Effects of a WHO-guided digital health intervention for depression in Syrian refugees in Lebanon: A randomized controlled trial
PLOS Medicine: published June 23, 2022 | https://doi.org/10.1371/journal.pmed.1004025
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Corrections
Correction: Association of physical activity intensity and bout length with mortality: An observational study of 79,503 UK Biobank participants
PLOS Medicine: published June 1, 2022 | https://doi.org/10.1371/journal.pmed.1004020
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Correction: School performance in Danish children exposed to maternal type 1 diabetes in utero: A nationwide retrospective cohort study
PLOS Medicine: published June 3, 2022 | https://doi.org/10.1371/journal.pmed.1004021