In recent decades, responses to HIV/AIDS and other important and large-scale threats to health have often employed intensive "vertical" approaches to prevention, diagnosis and treatment of specific diseases. Despite substantial progress, much remains to be done to achieve and sustain ambitions set out in global projects that include the Sustainable Development Goals. As part of this framework, a transition is occurring to provision of integrated disease responses within the context of strengthened health systems in developing countries. In a Policy Forum, Jan Hontelez and co-authors discuss the use of different levels of evidence and diverse implementation strategies to inform HIV programme integration.
Image Credit: Scott Graham, Unsplash
Perspective
COVID-19 in Africa: Catalyzing change for sustainable development
PLOS Medicine: published November 29, 2021 | https://doi.org/10.1371/journal.pmed.1003869
Policy Forums
Evidence-based policymaking when evidence is incomplete: The case of HIV programme integration
PLOS Medicine: published November 9, 2021 | https://doi.org/10.1371/journal.pmed.1003835
Related Articles
Lay testing cadres and point-of-care diagnostic tests for HIV and other diseases: An essential combination in health service delivery
PLOS Medicine: published November 24, 2021 | https://doi.org/10.1371/journal.pmed.1003867
Research Articles
Remission, relapse, and risk of major cardiovascular events after metabolic surgery in persons with hypertension: A Swedish nationwide registry-based cohort study
PLOS Medicine: published November 1, 2021 | https://doi.org/10.1371/journal.pmed.1003817
Opioid prescribing among new users for non-cancer pain in the USA, Canada, UK, and Taiwan: A population-based cohort study
PLOS Medicine: published November 1, 2021 | https://doi.org/10.1371/journal.pmed.1003829
Alcohol abstinence and mortality in a general population sample of adults in Germany: A cohort study
PLOS Medicine: published November 2, 2021 | https://doi.org/10.1371/journal.pmed.1003819
Liveable residential space, residential density, and hypertension in Hong Kong: A population-based cohort study
PLOS Medicine: published November 2, 2021 | https://doi.org/10.1371/journal.pmed.1003824
Epidemiology of type 2 diabetes remission in Scotland in 2019: A cross-sectional population-based study
PLOS Medicine: published November 2, 2021 | https://doi.org/10.1371/journal.pmed.1003828
Vaccination uptake amongst older adults from minority ethnic backgrounds: A systematic review
PLOS Medicine: published November 4, 2021 | https://doi.org/10.1371/journal.pmed.1003826
SARS-CoV-2 vaccine uptake in a multi-ethnic UK healthcare workforce: A cross-sectional study
PLOS Medicine: published November 5, 2021 | https://doi.org/10.1371/journal.pmed.1003823
Drug-induced orthostatic hypotension: A systematic review and meta-analysis of randomised controlled trials
PLOS Medicine: published November 9, 2021 | https://doi.org/10.1371/journal.pmed.1003821
Integrating HIV services and other health services: A systematic review and meta-analysis
PLOS Medicine: published November 9, 2021 | https://doi.org/10.1371/journal.pmed.1003836
Related Articles
Community control strategies for scabies: A cluster randomised noninferiority trial
PLOS Medicine: published November 10, 2021 | https://doi.org/10.1371/journal.pmed.1003849
Grade repetition and bullying victimization in adolescents: A global cross-sectional study of the Program for International Student Assessment (PISA) data from 2018
PLOS Medicine: published November 11, 2021 | https://doi.org/10.1371/journal.pmed.1003846
An intervention to improve teacher well-being support and training to support students in UK high schools (the WISE study): A cluster randomised controlled trial
PLOS Medicine: published November 11, 2021 | https://doi.org/10.1371/journal.pmed.1003847
Small area variations and factors associated with blood pressure and body-mass index in adult women in Accra, Ghana: Bayesian spatial analysis of a representative population survey and census data
PLOS Medicine: published November 11, 2021 | https://doi.org/10.1371/journal.pmed.1003850
Educational and health outcomes of schoolchildren in local authority care in Scotland: A retrospective record linkage study
PLOS Medicine: published November 12, 2021 | https://doi.org/10.1371/journal.pmed.1003832
Consumption of coffee and tea and risk of developing stroke, dementia, and poststroke dementia: A cohort study in the UK Biobank
PLOS Medicine: published November 16, 2021 | https://doi.org/10.1371/journal.pmed.1003830
Exposure to duloxetine during pregnancy and risk of congenital malformations and stillbirth: A nationwide cohort study in Denmark and Sweden
PLOS Medicine: published November 22, 2021 | https://doi.org/10.1371/journal.pmed.1003851
Adverse pregnancy outcomes in women with diabetes-related microvascular disease and risks of disease progression in pregnancy: A systematic review and meta-analysis
PLOS Medicine: published November 22, 2021 | https://doi.org/10.1371/journal.pmed.1003856
Prevalence and determinants of healthcare avoidance during the COVID-19 pandemic: A population-based cross-sectional study
PLOS Medicine: published November 23, 2021 | https://doi.org/10.1371/journal.pmed.1003854
Cash transfers for HIV prevention: A systematic review
PLOS Medicine: published November 29, 2021 | https://doi.org/10.1371/journal.pmed.1003866
Disease-related income and economic productivity loss in New Zealand: A longitudinal analysis of linked individual-level data
PLOS Medicine: published November 30, 2021 | https://doi.org/10.1371/journal.pmed.1003848
Obstetrical outcomes and maternal morbidities associated with COVID-19 in pregnant women in France: A national retrospective cohort study
PLOS Medicine: published November 30, 2021 | https://doi.org/10.1371/journal.pmed.1003857
Correction
Correction: Ambient and household PM2.5 pollution and adverse perinatal outcomes: A meta-regression and analysis of attributable global burden for 204 countries and territories
PLOS Medicine: published November 2, 2021 | https://doi.org/10.1371/journal.pmed.1003852