Since the emergence of SARS-CoV-2 infections at the end of 2019, COVID-19 has imposed a severe burden of illness and mortality on the world’s population. Amid uncertain national and international efforts to contain the spread of infection through non-pharmacological means such as restrictions on lifestyles and travel, intensive clinical research has been carried out to develop treatments for patients with COVID-19, alongside urgent programs to create vaccines able to prevent further infections. In a research article in PLOS Medicine, Min Seo Kim and co-workers report a systematic review and network meta-analysis of evidence from randomized trials and observational studies on pharmacological treatments for COVID-19.
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Research Articles
Mortality and major disease risk among migrants of the 1991–2001 Balkan wars to Sweden: A register-based cohort study
PLOS Medicine: published December 1, 2020 | https://doi.org/10.1371/journal.pmed.1003392
Effects of vitamin B12 supplementation on neurodevelopment and growth in Nepalese Infants: A randomized controlled trial
PLOS Medicine: published December 1, 2020 | https://doi.org/10.1371/journal.pmed.1003430
Intake of dietary fats and fatty acids and the incidence of type 2 diabetes: A systematic review and dose-response meta-analysis of prospective observational studies
PLOS Medicine: published December 2, 2020 | https://doi.org/10.1371/journal.pmed.1003347
Trade-offs between cost and accuracy in active case finding for tuberculosis: A dynamic modelling analysis
PLOS Medicine: published December 2, 2020 | https://doi.org/10.1371/journal.pmed.1003456
Dose-dependent oral glucocorticoid cardiovascular risks in people with immune-mediated inflammatory diseases: A population-based cohort study
PLOS Medicine: published December 3, 2020 | https://doi.org/10.1371/journal.pmed.1003432
Evaluating the relationship between alcohol consumption, tobacco use, and cardiovascular disease: A multivariable Mendelian randomization study
PLOS Medicine: published December 4, 2020 | https://doi.org/10.1371/journal.pmed.1003410
Bariatric surgery for patients with type 2 diabetes mellitus requiring insulin: Clinical outcome and cost-effectiveness analyses
PLOS Medicine: published December 7, 2020 | https://doi.org/10.1371/journal.pmed.1003228
Antenatal corticosteroid administration and early school age child development: A regression discontinuity study in British Columbia, Canada
PLOS Medicine: published December 7, 2020 | https://doi.org/10.1371/journal.pmed.1003435
Duration of obesity exposure between ages 10 and 40 years and its relationship with cardiometabolic disease risk factors: A cohort study
PLOS Medicine: published December 8, 2020 | https://doi.org/10.1371/journal.pmed.1003387
Induction of labour at 41 weeks or expectant management until 42 weeks: A systematic review and an individual participant data meta-analysis of randomised trials
PLOS Medicine: published December 8, 2020 | https://doi.org/10.1371/journal.pmed.1003436
Sweetened beverages and risk of frailty among older women in the Nurses’ Health Study: A cohort study
PLOS Medicine: published December 8, 2020 | https://doi.org/10.1371/journal.pmed.1003453
Associations among circulating sphingolipids, β-cell function, and risk of developing type 2 diabetes: A population-based cohort study in China
PLOS Medicine: published December 9, 2020 | https://doi.org/10.1371/journal.pmed.1003451
A combination of urinary biomarker panel and PancRISK score for earlier detection of pancreatic cancer: A case–control study
PLOS Medicine: published December 10, 2020 | https://doi.org/10.1371/journal.pmed.1003489
The potential impact of urine-LAM diagnostics on tuberculosis incidence and mortality: A modelling analysis
PLOS Medicine: published December 11, 2020 | https://doi.org/10.1371/journal.pmed.1003466
Hospitalizations among adults with chronic kidney disease in the United States: A cohort study
PLOS Medicine: published December 11, 2020 | https://doi.org/10.1371/journal.pmed.1003470
Thresholds of glycemia, insulin therapy, and risk for severe retinopathy in premature infants: A cohort study
PLOS Medicine: published December 11, 2020 | https://doi.org/10.1371/journal.pmed.1003477
Impact of scaling up dolutegravir on antiretroviral resistance in South Africa: A modeling study
PLOS Medicine: published December 14, 2020 | https://doi.org/10.1371/journal.pmed.1003397
Genetic associations with temporal shifts in obesity and severe obesity during the obesity epidemic in Norway: A longitudinal population-based cohort (the HUNT Study)
PLOS Medicine: published December 14, 2020 | https://doi.org/10.1371/journal.pmed.1003452
Cardiovascular health metrics from mid- to late-life and risk of dementia: A population-based cohort study in Finland
PLOS Medicine: published December 15, 2020 | https://doi.org/10.1371/journal.pmed.1003474
Long-term health outcomes of people with reduced kidney function in the UK: A modelling study using population health data
PLOS Medicine: published December 16, 2020 | https://doi.org/10.1371/journal.pmed.1003478
Impact of food supplements on early child development in children with moderate acute malnutrition: A randomised 2 x 2 x 3 factorial trial in Burkina Faso
PLOS Medicine: published December 23, 2020 | https://doi.org/10.1371/journal.pmed.1003442
Association of macro-level determinants with adolescent overweight and suicidal ideation with planning: A cross-sectional study of 21 Latin American and Caribbean Countries
PLOS Medicine: published December 29, 2020 | https://doi.org/10.1371/journal.pmed.1003443
Assessing the risk of ketoacidosis due to sodium-glucose cotransporter (SGLT)-2 inhibitors in patients with type 1 diabetes: A meta-analysis and meta-regression
PLOS Medicine: published December 29, 2020 | https://doi.org/10.1371/journal.pmed.1003461
Corrections
Correction: Impact of self-imposed prevention measures and short-term government-imposed social distancing on mitigating and delaying a COVID-19 epidemic: A modelling study
PLOS Medicine: published December 4, 2020 | https://doi.org/10.1371/journal.pmed.1003499
Related Articles
Correction: Interventions for treatment of COVID-19: A living systematic review with meta-analyses and trial sequential analyses (The LIVING Project)
PLOS Medicine: published December 29, 2020 | https://doi.org/10.1371/journal.pmed.1003517