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Table of Contents

January 2006

Cover

Matter Out of Place.
Issue Image

Gerrell Crichton uses digital imaging, video installation, and public performance to explore subjects such as purity, perverse memory, and little disasters. Originally from the East Coast, she has lived in San Francisco for many years and teaches Intermedia Art at the University of California Santa Cruz. Crichton's work has been exhibited nationally and internationally since 1993 in Norway, England, Australia, New Zealand, and the United States. She has received grants and awards from many sources, including the Creative Work Fund, the KunsthØgskolen in Bergen, Norway, the Astraea Foundation, Art Matters, the San Francisco Arts Commission, the MacDowell Colony, and the Virginia Center for the Creative Arts. The Matter Out of Place project has been supported by grants from the University of California Arts Research Institute and the University of California Santa Cruz Academic Senate.

Image Credit: Gerrell Crichton (egc8 [at] earthlink.net)

Editorial

What Are the Priorities in Malaria Research?

PLOS Medicine: published January 31, 2006 | https://doi.org/10.1371/journal.pmed.0030083

Essay

The Science and Politics of Colorectal Cancer Screening

Geir Hoff, Michael Bretthauer

PLOS Medicine: published January 3, 2006 | https://doi.org/10.1371/journal.pmed.0030036

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Perspectives

Is Antiretroviral Therapy Cost-Effective in South Africa?

R. Scott Braithwaite, Joel Tsevat

PLOS Medicine: published January 31, 2006 | https://doi.org/10.1371/journal.pmed.0030060

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Trends in Cholera Epidemiology

Claudia T Codeço, Flavio C Coelho

PLOS Medicine: published January 31, 2006 | https://doi.org/10.1371/journal.pmed.0030042

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New Approaches to Vaccine Adjuvants: Inhibiting the Inhibitor

Barney S Graham

PLOS Medicine: published January 3, 2006 | https://doi.org/10.1371/journal.pmed.0030057

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Glioblastoma Multiforme—Treating a Deadly Tumor with Both Strands of RNA

Robert J Weil

PLOS Medicine: published December 6, 2005 | https://doi.org/10.1371/journal.pmed.0030031

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Health in Action

Preventing Fetal Alcohol Spectrum Disorder in Aboriginal Communities: A Methods Development Project

Paul Masotti, M. Anne George, Karen Szala-Meneok, A. Michel Morton, Christine Loock, Marilyn Van Bibber, Jennifer Ranford, Michael Fleming, Stuart MacLeod

PLOS Medicine: published January 10, 2006 | https://doi.org/10.1371/journal.pmed.0030008

Policy Forums

The New International Health Regulations and the Federalism Dilemma

Kumanan Wilson, Christopher McDougall, Ross Upshur

PLOS Medicine: published December 20, 2005 | https://doi.org/10.1371/journal.pmed.0030001

Perspectives on the Efficacy of Antidepressants for Child and Adolescent Depression

Amir Raz

PLOS Medicine: published December 20, 2005 | https://doi.org/10.1371/journal.pmed.0030009

Student Forum

The “PharmFree” Campaign: Educating Medical Students about Industry Influence

Yavar Moghimi

PLOS Medicine: published January 31, 2006 | https://doi.org/10.1371/journal.pmed.0030030

Learning Forum

A 40-Year-Old Woman Who Developed Jaundice during Therapy for Thyrotoxicosis

Chukwuma Ogbonna Ekpebegh, Naomi Sharlene Levitt

PLOS Medicine: published January 31, 2006 | https://doi.org/10.1371/journal.pmed.0030012

Case Report

A Pediatric Genetic Disorder Diagnosed in Adulthood

Joseph A Church

PLOS Medicine: published January 31, 2006 | https://doi.org/10.1371/journal.pmed.0030015

Research Articles

Cost-Effectiveness of Highly Active Antiretroviral Therapy in South Africa

Motasim Badri, Gary Maartens, Sundhiya Mandalia, Linda-Gail Bekker, John R Penrod, Robert W Platt, Robin Wood, Eduard J Beck

PLOS Medicine: published December 6, 2005 | https://doi.org/10.1371/journal.pmed.0030004

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Limits to Forecasting Precision for Outbreaks of Directly Transmitted Diseases

John M Drake

PLOS Medicine: published November 22, 2005 | https://doi.org/10.1371/journal.pmed.0030003

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  1. The Difficulties of Predicting the Outbreak Sizes of Epidemics

Hyperinfectivity: A Critical Element in the Ability of V. cholerae to Cause Epidemics?

David M Hartley, J. Glenn Morris Jr, David L Smith

PLOS Medicine: published December 6, 2005 | https://doi.org/10.1371/journal.pmed.0030007

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  2. Adjusting Cholera Models to Recent Experimental Data
  3. Hyperinfectivity in Cholera: A New Mechanism for an Old Epidemiological Model?

Maternal–Fetal Microtransfusions and HIV-1 Mother-to-Child Transmission in Malawi

Jesse J Kwiek, Victor Mwapasa, Danny A Milner Jr, Alisa P Alker, William C Miller, Eyob Tadesse, Malcolm E Molyneux, Stephen J Rogerson, Steven R Meshnick

PLOS Medicine: published November 22, 2005 | https://doi.org/10.1371/journal.pmed.0030010

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An Alternative and Effective HIV Vaccination Approach Based on Inhibition of Antigen Presentation Attenuators in Dendritic Cells

Xiao-Tong Song, Kevin Evel-Kabler, Lisa Rollins, Melissa Aldrich, Feng Gao, Xue F Huang, Si-Yi Chen

PLOS Medicine: published January 3, 2006 | https://doi.org/10.1371/journal.pmed.0030011

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  2. Taking an Alternative Approach to HIV Vaccination

Antibodies against Human Cytomegalovirus in the Pathogenesis of Systemic Sclerosis: A Gene Array Approach

Claudio Lunardi, Marzia Dolcino, Dimitri Peterlana, Caterina Bason, Riccardo Navone, Nicola Tamassia, Ruggero Beri, Roberto Corrocher, Antonio Puccetti

PLOS Medicine: published December 6, 2005 | https://doi.org/10.1371/journal.pmed.0030002

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CFH Y402H Confers Similar Risk of Soft Drusen and Both Forms of Advanced AMD

Kristinn P Magnusson, Shan Duan, Haraldur Sigurdsson, Hjorvar Petursson, Zhenglin Yang, Yu Zhao, Paul S Bernstein, Jian Ge, Fridbert Jonasson, Einar Stefansson, Gudleif Helgadottir, Norman A Zabriskie, Thorlakur Jonsson, Asgeir Björnsson, Theodora Thorlacius, Palmi V Jonsson, Gudmar Thorleifsson, Augustine Kong, Hreinn Stefansson, Kang Zhang, Kari Stefansson, Jeffrey R Gulcher

PLOS Medicine: published November 29, 2005 | https://doi.org/10.1371/journal.pmed.0030005

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Gene Expression Profiling Predicts Survival in Conventional Renal Cell Carcinoma

Hongjuan Zhao, Börje Ljungberg, Kjell Grankvist, Torgny Rasmuson, Robert Tibshirani, James D Brooks

PLOS Medicine: published December 6, 2005 | https://doi.org/10.1371/journal.pmed.0030013

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EGF Receptor-Targeted Synthetic Double-Stranded RNA Eliminates Glioblastoma, Breast Cancer, and Adenocarcinoma Tumors in Mice

Alexei Shir, Manfred Ogris, Ernst Wagner, Alexander Levitzki

PLOS Medicine: published December 6, 2005 | https://doi.org/10.1371/journal.pmed.0030006

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Correspondence

The Protective Effect of Male Circumcision as a Faith Lift for the Troubled Paradigm of HIV Epidemiology in Sub-Saharan Africa

John J Potterat, Devon D Brewer, Stephen Q Muth, Stuart Brody

PLOS Medicine: published January 31, 2006 | https://doi.org/10.1371/journal.pmed.0030064

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Estimated Protection Too Conservative

James D Shelton

PLOS Medicine: published January 31, 2006 | https://doi.org/10.1371/journal.pmed.0030065

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Two Groups Not on All Fours

Hugh Young

PLOS Medicine: published January 31, 2006 | https://doi.org/10.1371/journal.pmed.0030075

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Rubbery Figures?

Michael Glass

PLOS Medicine: published January 31, 2006 | https://doi.org/10.1371/journal.pmed.0030070

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The Money Issue

Mpho Selemogo

PLOS Medicine: published January 31, 2006 | https://doi.org/10.1371/journal.pmed.0030073

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Authors' Reply

Bertran Auvert, Joëlle Sobngwi-Tambekou, Dirk Taljaard, Emmanuel Lagarde, Adrian Puren

PLOS Medicine: published January 31, 2006 | https://doi.org/10.1371/journal.pmed.0030067

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Male Circumcision and HIV Control in Africa

Michel Garenne

PLOS Medicine: published January 31, 2006 | https://doi.org/10.1371/journal.pmed.0030078

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PfHRP2 Measures Schizogony, Not Mechanical Blockage

Ian Clark

PLOS Medicine: published January 31, 2006 | https://doi.org/10.1371/journal.pmed.0030068

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  2. Estimation of the Total Parasite Biomass in Acute Falciparum Malaria from Plasma PfHRP2

Authors' Reply: Response to Ian Clark

Arjen Dondorp, Nick White, Nick Day

PLOS Medicine: published January 31, 2006 | https://doi.org/10.1371/journal.pmed.0030069

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  2. PfHRP2 Measures Schizogony, Not Mechanical Blockage

Major Potential Confounder Not Addressed

Jennifer Vines

PLOS Medicine: published January 31, 2006 | https://doi.org/10.1371/journal.pmed.0030063

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On Evidence in Support of Male Circumcision in HIV Prevention: What Next?

Adamson Sinjani Muula

PLOS Medicine: published January 31, 2006 | https://doi.org/10.1371/journal.pmed.0030066

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Rush to Judgment

Richard Winkel

PLOS Medicine: published January 31, 2006 | https://doi.org/10.1371/journal.pmed.0030071

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Male Circumcision Increases Risk for Females

Jonathan Sykes

PLOS Medicine: published January 31, 2006 | https://doi.org/10.1371/journal.pmed.0030072

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Male Circumcision and HIV in Africa

Taiwo Lawoyin, O. A Kehinde

PLOS Medicine: published January 31, 2006 | https://doi.org/10.1371/journal.pmed.0030074

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