Figures
Fig 3 panel B contains a mislabeled axis. The label ‘Pre—HIV negative’ should be ‘Post—HIV negative.’ Please see the correct Fig 3 below.
(A) Cellular immune response to wild-type spike by ELISpot assay (Pre, n = 23; Post, n = 45): IFN-γ SFCs after subtraction of MOG. Statistics performed using Mann–Whitney U test: p = 0.002. Negative responses: Pre, 8; Post, 5. (B) Cellular immune response to wild-type and Delta spike in AIM assay (n = 14): percentage of CD4+ CD137+ OX40+ T-cells after subtraction of DMSO. Dotted line shows the LLoD at 0.001%. Statistics between pre- and post-vaccination for WT in PLWH performed using Wilcoxon matched-pairs signed rank test (p = 0.005); pre- and post-vaccination for Delta: ns. Statistics between PLWH and controls with Mann–Whitney U test: not significant. (C) Cellular immune response to wild-type and Delta spike in AIM assay (n = 14): percentage of CD8+ CD137+ CD69+ T-cells after subtraction of DMSO. Dotted line shows the LLoD at 0.001%. Statistics performed using Wilcoxon matched-pairs signed rank test (p = 0.008); pre- and post-vaccination for Delta: ns. Statistics between PLWH and controls with Mann–Whitney U test: not significant. Green circles: mRNA vaccines; blue squares: vector-based vaccines. Pre: before vaccination; Post: 4–6 weeks after second vaccination. AIM, activation-induced marker; BAU, binding antibody units; cART, combination antiretroviral therapy; DMSO, dimethyl sulfoxide; ELISpot, enzyme-linked immune absorbent spot; GMC, geometric mean concentration; INF-γ, interferon-γ; LLoD, lower limit of detection; MOG, myelin oligodendrocyte glycoprotein; PBMC, peripheral blood mononuclear cell; PLWH, people living with HIV; SFC, spot-forming cell; WT, wild type.
Reference
- 1. Hensley KS, Jongkees MJ, Geers D, GeurtsvanKessel CH, Mueller YM, Dalm VASH, et al. (2022) Immunogenicity and reactogenicity of SARS-CoV-2 vaccines in people living with HIV in the Netherlands: A nationwide prospective cohort study. PLoS Med 19(10): e1003979. https://doi.org/10.1371/journal.pmed.1003979 pmid:36301821
Citation: Hensley KS, Jongkees MJ, Geers D, GeurtsvanKessel CH, Mueller YM, Dalm VASH, et al. (2023) Correction: Immunogenicity and reactogenicity of SARS-CoV-2 vaccines in people living with HIV in the Netherlands: A nationwide prospective cohort study. PLoS Med 20(1): e1004159. https://doi.org/10.1371/journal.pmed.1004159
Published: January 6, 2023
Copyright: © 2023 Hensley et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.