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Comprehensive reporting of clinical trial design, conduct and analyses is crucial for the accurate interpretation of trial results. In this issue, the CONSORT 2025 statement and SPIRIT 2025 statement provide updated guidance on reporting randomised clinical trials and protocols to improve reporting quality and facilitate more transparent communication of clinical trial data and design. This accompanying Editorial, written on behalf of the PLOS Medicine editors, delves into the power that improving clinical trial reporting can ultimately confer to trial design and reproducibility.
Image Credit: Laura James
Citation: (2025) PLoS Medicine Issue Image | Vol. 22(4) May 2025. PLoS Med 22(4): ev22.i04. https://doi.org/10.1371/image.pmed.v22.i04
Published: May 7, 2025
Copyright: © 2025 . This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Comprehensive reporting of clinical trial design, conduct and analyses is crucial for the accurate interpretation of trial results. In this issue, the CONSORT 2025 statement and SPIRIT 2025 statement provide updated guidance on reporting randomised clinical trials and protocols to improve reporting quality and facilitate more transparent communication of clinical trial data and design. This accompanying Editorial, written on behalf of the PLOS Medicine editors, delves into the power that improving clinical trial reporting can ultimately confer to trial design and reproducibility.
Image Credit: Laura James