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PLoS Medicine Issue Image | Vol. 19(8) September 2022

Existing evidence supports associations between higher lipoprotein levels and risk of atherosclerosis and coronary artery disease, conditions which are in turn associated with an increase in the risk of atrial fibrillation. However, seemingly discordant evidence also suggests higher levels of blood lipids are associated with reduced risk of atrial fibrillation. In a Perspective, Dimitrios Sagris, Stephanie Harrison, and Gregory Lip discuss an accompanying research article from Mozhu Ding and colleagues that presents new evidence concerning this paradoxical relationship between circulating lipids and risk of future atrial fibrillation.

Image Credit: Towfiqu barbhuiya, Unsplash

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Existing evidence supports associations between higher lipoprotein levels and risk of atherosclerosis and coronary artery disease, conditions which are in turn associated with an increase in the risk of atrial fibrillation. However, seemingly discordant evidence also suggests higher levels of blood lipids are associated with reduced risk of atrial fibrillation. In a Perspective, Dimitrios Sagris, Stephanie Harrison, and Gregory Lip discuss an accompanying research article from Mozhu Ding and colleagues that presents new evidence concerning this paradoxical relationship between circulating lipids and risk of future atrial fibrillation.

Image Credit: Towfiqu barbhuiya, Unsplash

https://doi.org/10.1371/image.pmed.v19.i08.g001