Predicting knee osteoarthritis progression using neural network with longitudinal MRI radiomics, and biochemical biomarkers: A modeling study

• Ting Wang ,

  Roles Data curation, Methodology, Writing – original draft

  ¶☯ These authors were dual first authors and contributed equally to this work.

  Affiliations Department of Orthopaedics, The Third People’s Hospital of Chengdu, Affiliated Hospital of Southwest Jiaotong University & The Second Affiliated Hospital of Chengdu, Chongqing Medical University, Chengdu, Sichuan, China, Medical Research Center, The Third People’s Hospital of Chengdu, Affiliated Hospital of Southwest Jiaotong University & The Second Affiliated Hospital of Chengdu, Chongqing Medical University, Chengdu, Sichuan, China

  https://orcid.org/0000-0002-1309-0194

  ⨯
• Hao Liu ,

  Roles Methodology

  ¶☯ These authors were dual first authors and contributed equally to this work.

  Affiliation Department of Orthopaedics, The Third People’s Hospital of Chengdu, Affiliated Hospital of Southwest Jiaotong University & The Second Affiliated Hospital of Chengdu, Chongqing Medical University, Chengdu, Sichuan, China

  https://orcid.org/0009-0006-1273-4468

  ⨯
• Wenbo Zhao,

  Roles Methodology

  Affiliation Department of Orthopaedics, The Third People’s Hospital of Chengdu, Affiliated Hospital of Southwest Jiaotong University & The Second Affiliated Hospital of Chengdu, Chongqing Medical University, Chengdu, Sichuan, China

  ⨯
• Peihua Cao,

  Roles Formal analysis, Methodology

  Affiliation Clinical Research Centre, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China

  ⨯
• Jia Li,

  Roles Formal analysis, Methodology

  Affiliation Division of Orthopaedic Surgery, Department of Orthopaedics, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China

  https://orcid.org/0000-0003-3572-3690

  ⨯
• Tianyu Chen,

  Roles Conceptualization, Methodology, Software

  Affiliation Department of Orthopaedics, The Third Affiliated Hospital of Southern Medical University, Guangzhou, Guangdong, China

  ⨯
• Guangfeng Ruan,

  Roles Methodology, Software

  Affiliation Clinical Research Centre, Guangzhou First People’s Hospital, School of Medicine, South China University of Technology, Guangdong, Guangzhou, China

  ⨯
• Yan Zhang,

  Roles Methodology, Validation

  Affiliation Clinical Research Centre, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China

  https://orcid.org/0000-0001-9126-4922

  ⨯
• Xiaoshuai Wang,

  Roles Formal analysis, Methodology

  Affiliation Clinical Research Centre, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China

  https://orcid.org/0000-0002-3895-1384

  ⨯
• Qin Dang,

  Roles Investigation, Methodology

  Affiliations Clinical Research Centre, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China, Department of Orthopaedics, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China

  ⨯
• Mengdi Zhang,

  Roles Methodology, Software

  Affiliations Clinical Research Centre, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China, Department of Orthopaedics, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China

  ⨯
• Alexander Tack,

  Roles Methodology, Software

  Affiliation Zuse Institute Berlin, Berlin, Germany

  ⨯
• David Hunter,

  Roles Writing – review & editing

  Affiliations Clinical Research Centre, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China, Department of Rheumatology, Royal North Shore Hospital and Sydney Musculoskeletal Health, Kolling Institute, University of Sydney, Sydney, New South Wales, Australia

  https://orcid.org/0000-0003-3197-752X

  ⨯
• Changhai Ding ,

  Roles Conceptualization, Data curation, Funding acquisition, Supervision, Writing – review & editing

  * E-mail: lisheng-fa@qq.com (SL); changhai.ding@utas.edu.au (CD)

  Affiliations Clinical Research Centre, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China, Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia

  https://orcid.org/0000-0002-9479-730X

  ⨯
• Shengfa Li

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – review & editing

  * E-mail: lisheng-fa@qq.com (SL); changhai.ding@utas.edu.au (CD)

  Affiliation Department of Orthopaedics, The Third People’s Hospital of Chengdu, Affiliated Hospital of Southwest Jiaotong University & The Second Affiliated Hospital of Chengdu, Chongqing Medical University, Chengdu, Sichuan, China

  https://orcid.org/0009-0005-6801-7102

  ⨯