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Open Access
Peer-reviewed
Research Article
Evaluating the impact of differentiated service delivery (DSD) on retention in care and HIV viral suppression in South Africa: A target trial emulation using routine healthcare data
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Amy N. Huber ,
Contributed equally to this work with: Amy N. Huber, Lise Jamieson
Roles Conceptualization, Data curation, Formal analysis, Project administration, Writing – original draft, Writing – review & editing
* E-mail: ahuber@heroza.org
Affiliation Health Economics and Epidemiology Research Office, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
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Lise Jamieson ,
Contributed equally to this work with: Amy N. Huber, Lise Jamieson
Roles Conceptualization, Data curation, Formal analysis, Methodology, Writing – original draft, Writing – review & editing
Affiliations Health Economics and Epidemiology Research Office, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa, South African Centre for Epidemiological Modelling and Analysis (SACEMA), Stellenbosch University, Stellenbosch, South Africa
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Matthew P. Fox,
Roles Conceptualization, Formal analysis, Methodology, Writing – original draft
Affiliations Health Economics and Epidemiology Research Office, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa, Department of Global Health, Boston University School of Public Health, Boston, Massachusetts, United States of America
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Musa Manganye,
Roles Validation, Writing – review & editing
Affiliation National Department of Health, South African Government, Pretoria, South Africa
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Lufuno Malala,
Roles Validation, Writing – review & editing
Affiliation National Department of Health, South African Government, Pretoria, South Africa
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Thato Chidarikire,
Roles Validation, Writing – review & editing
Affiliation World Health Organization, Geneva, Switzerland
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Nthabiseng Khoza,
Roles Validation, Writing – review & editing
Affiliation National Department of Health, South African Government, Pretoria, South Africa
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Brooke E. Nichols,
Roles Conceptualization, Writing – review & editing
Affiliations Department of Global Health, Boston University School of Public Health, Boston, Massachusetts, United States of America, Department of Global Health, Amsterdam Institute for Global Health and Development, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands
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Sydney Rosen,
Roles Conceptualization, Funding acquisition, Writing – original draft, Writing – review & editing
Affiliations Health Economics and Epidemiology Research Office, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa, Department of Global Health, Boston University School of Public Health, Boston, Massachusetts, United States of America
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Sophie Pascoe
Roles Funding acquisition, Project administration, Writing – review & editing
Affiliation Health Economics and Epidemiology Research Office, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
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Evaluating the impact of differentiated service delivery (DSD) on retention in care and HIV viral suppression in South Africa: A target trial emulation using routine healthcare data
- Amy N. Huber,
- Lise Jamieson,
- Matthew P. Fox,
- Musa Manganye,
- Lufuno Malala,
- Thato Chidarikire,
- Nthabiseng Khoza,
- Brooke E. Nichols,
- Sydney Rosen,
- Sophie Pascoe
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- Published: August 26, 2025
- https://doi.org/10.1371/journal.pmed.1004489