Methaemoglobin as a surrogate marker of primaquine antihypnozoite activity in Plasmodium vivax malaria: A systematic review and individual patient data meta-analysis

• Ihsan Fadilah ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Project administration, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: ifadilah@oucru.org (IF); jwatowatson@gmail.com (JAW)

  Affiliations Oxford University Clinical Research Unit Indonesia, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia, Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom

  https://orcid.org/0000-0001-9507-6427

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• Robert J. Commons,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Resources, Supervision, Writing – original draft, Writing – review & editing

  Affiliations Menzies School of Health Research, Charles Darwin University, Darwin, Australia, WorldWide Antimalarial Resistance Network, Asia-Pacific Regional Hub–Australia, Melbourne, Australia, General and Subspecialty Medicine, Grampians Health, Ballarat, Australia

  https://orcid.org/0000-0002-3359-5632

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• Nguyen Hoang Chau,

  Roles Resources, Writing – review & editing

  Affiliation Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam

  https://orcid.org/0000-0002-7826-3850

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• Cindy S. Chu,

  Roles Resources, Writing – review & editing

  Affiliations Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom, Shoklo Malaria Research Unit, Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Mae Sot, Thailand

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• Nicholas P. J. Day,

  Roles Resources, Writing – review & editing

  Affiliations Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom, Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand

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• Gavin C. K. W. Koh,

  Roles Resources, Writing – review & editing

  Affiliation Formerly Senior Director, Global Health, GlaxoSmithKline, Brentford, United Kingdom

  https://orcid.org/0000-0002-7336-1566

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• Justin A. Green,

  Roles Resources, Writing – review & editing

  Affiliation Department of Infectious Diseases, Northwick Park Hospital, Harrow, United Kingdom

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• Marcus VG Lacerda,

  Roles Resources, Writing – review & editing

  Affiliations Fundação de Medicina Tropical Dr Heitor Vieira Dourado, Manaus, Brazil, Instituto Leônidas e Maria Deane, Fiocruz, Manaus, Brazil, University of Texas Medical Branch, Galveston, Texas, United States of America

  https://orcid.org/0000-0003-3374-9985

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• Alejandro Llanos-Cuentas,

  Roles Resources, Writing – review & editing

  Affiliation Universidad Peruana Cayetano Heredia, Instituto de Medicina Tropical Alexander von Humboldt, Unit of Leishmaniasis and Malaria, Lima, Peru

  https://orcid.org/0000-0002-7567-5534

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• Erni J. Nelwan,

  Roles Resources, Writing – review & editing

  Affiliations Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Division of Tropical Medicine and Infectious Disease, Department of Internal Medicine, Cipto Mangunkusumo Hospital, Jakarta, Indonesia

  https://orcid.org/0000-0003-4064-5412

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• Francois Nosten,

  Roles Resources, Writing – review & editing

  Affiliations Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom, Shoklo Malaria Research Unit, Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Mae Sot, Thailand

  https://orcid.org/0000-0002-7951-0745

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• Ayodhia Pitaloka Pasaribu,

  Roles Resources, Writing – review & editing

  Affiliations Department of Pediatrics, Medical Faculty, Universitas Sumatera Utara, Medan, Indonesia, Tridarma Healthcare Empowerment Foundation, Medan, Indonesia

  https://orcid.org/0000-0002-3830-8073

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• Inge Sutanto,

  Roles Resources, Writing – review & editing

  Affiliation Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia

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• Walter R. J. Taylor,

  Roles Resources, Writing – review & editing

  Affiliations Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom, Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand

  https://orcid.org/0000-0001-6236-0464

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• Kamala Thriemer,

  Roles Resources, Writing – review & editing

  Affiliation Menzies School of Health Research, Charles Darwin University, Darwin, Australia

  https://orcid.org/0000-0001-7536-7497

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• Ric N. Price,

  Roles Conceptualization, Resources, Supervision, Writing – original draft, Writing – review & editing

  Affiliations Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom, Menzies School of Health Research, Charles Darwin University, Darwin, Australia, WorldWide Antimalarial Resistance Network, Asia-Pacific Regional Hub–Australia, Melbourne, Australia, Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand

  https://orcid.org/0000-0003-2000-2874

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• Nicholas J. White,

  Roles Conceptualization, Funding acquisition, Methodology, Resources, Supervision, Writing – original draft, Writing – review & editing

  Affiliations Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom, Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand

  https://orcid.org/0000-0002-1897-1978

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• J. Kevin Baird,

  Roles Conceptualization, Funding acquisition, Methodology, Resources, Supervision, Writing – original draft, Writing – review & editing

  Affiliations Oxford University Clinical Research Unit Indonesia, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia, Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom

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•  [ ... ],
• James A. Watson

  Roles Conceptualization, Formal analysis, Methodology, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: ifadilah@oucru.org (IF); jwatowatson@gmail.com (JAW)

  Affiliations Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom, Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam, Infectious Diseases Data Observatory, Oxford, United Kingdom

  https://orcid.org/0000-0001-5524-0325

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