Measuring protective efficacy and quantifying the impact of drug resistance: A novel malaria chemoprevention trial design and methodology

• Andria Mousa ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: Andria.Mousa@lshtm.ac.uk

  Affiliation Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom

  https://orcid.org/0000-0001-9406-7481

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• Gina Cuomo-Dannenburg,

  Roles Methodology, Resources, Software, Writing – review & editing

  Affiliation MRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom

  https://orcid.org/0000-0001-6821-0352

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• Hayley A. Thompson,

  Roles Methodology, Resources, Software, Writing – review & editing

  Affiliation Malaria and Neglected Tropical Diseases, PATH, Seattle, Washington, United States of America

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• R. Matthew Chico,

  Roles Conceptualization, Writing – review & editing

  Affiliation Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom

  https://orcid.org/0000-0003-1795-7100

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• Khalid B. Beshir,

  Roles Conceptualization, Writing – review & editing

  Affiliation Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom

  https://orcid.org/0000-0001-5108-8362

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• Colin J. Sutherland,

  Roles Conceptualization, Writing – review & editing

  Affiliation Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom

  https://orcid.org/0000-0003-1592-6407

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• David Schellenberg,

  Roles Conceptualization, Writing – review & editing

  Affiliation Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom

  https://orcid.org/0000-0001-8222-0186

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• Roly Gosling,

  Roles Conceptualization, Funding acquisition, Writing – review & editing

  Affiliations Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom, Malaria Elimination Initiative, Institute of Global Health, University of California, San Francisco, California, United States of America

  https://orcid.org/0000-0001-6291-0024

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• Michael Alifrangis,

  Roles Conceptualization, Writing – review & editing

  Affiliations Center for Medical Parasitology, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark, Department of Infectious Diseases, Copenhagen University Hospital, Copenhagen, Denmark

  https://orcid.org/0000-0002-3835-3333

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• Emma Filtenborg Hocke,

  Roles Conceptualization, Writing – review & editing

  Affiliations Center for Medical Parasitology, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark, Department of Infectious Diseases, Copenhagen University Hospital, Copenhagen, Denmark

  https://orcid.org/0000-0002-0040-7041

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• Helle Hansson,

  Roles Conceptualization, Writing – review & editing

  Affiliations Center for Medical Parasitology, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark, Department of Infectious Diseases, Copenhagen University Hospital, Copenhagen, Denmark

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• Ana Chopo-Pizarro,

  Roles Conceptualization, Writing – review & editing

  Affiliation Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom

  https://orcid.org/0000-0002-4330-4085

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• Wilfred F. Mbacham,

  Roles Conceptualization, Writing – review & editing

  Affiliations The Biotechnology Centre, University of Yaoundé, Yaoundé, Cameroon, The Fobang Institutes for Innovation in Science and Technology, Yaoundé, Cameroon, The Faculty of Northwest University, Faculty of Natural and Agricultural Sciences, Potchefstroom, South Africa

  https://orcid.org/0000-0002-3934-3233

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• Innocent M. Ali,

  Roles Conceptualization, Writing – review & editing

  Affiliations The Biotechnology Centre, University of Yaoundé, Yaoundé, Cameroon, Department of Biochemistry, Faculty of Science, University of Dschang, Dschang, Cameroon

  https://orcid.org/0000-0002-1112-6376

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• Mike Chaponda,

  Roles Conceptualization, Writing – review & editing

  Affiliation Department of Clinical Sciences, Tropical Diseases Research Centre, Ndola, Zambia

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• Cally Roper ,

  Contributed equally to this work with: Cally Roper, Lucy C. Okell

  Roles Conceptualization, Supervision, Writing – review & editing

  Affiliation Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom

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•  [ ... ],
• Lucy C. Okell

  Contributed equally to this work with: Cally Roper, Lucy C. Okell

  Roles Conceptualization, Methodology, Resources, Software, Supervision, Writing – review & editing

  Affiliation MRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom

  https://orcid.org/0000-0001-7202-6873

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