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Open Access
Peer-reviewed
Research Article
Blood-based epigenome-wide analyses of 19 common disease states: A longitudinal, population-based linked cohort study of 18,413 Scottish individuals
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Robert F. Hillary,
Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Software, Visualization, Writing – original draft, Writing – review & editing
Affiliation Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom
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Daniel L. McCartney,
Roles Data curation, Formal analysis, Methodology, Software, Writing – review & editing
Affiliation Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom
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Hannah M. Smith,
Roles Software, Writing – review & editing
Affiliation Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom
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Elena Bernabeu,
Roles Formal analysis, Methodology, Writing – review & editing
Affiliation Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom
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Danni A. Gadd,
Roles Formal analysis, Methodology, Writing – review & editing
Affiliation Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom
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Aleksandra D. Chybowska,
Roles Software, Writing – review & editing
Affiliation Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom
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Yipeng Cheng,
Roles Software, Writing – review & editing
Affiliation Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom
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Lee Murphy,
Roles Data curation, Writing – review & editing
Affiliation Edinburgh Clinical Research Facility, University of Edinburgh, Edinburgh, United Kingdom
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Nicola Wrobel,
Roles Data curation, Writing – review & editing
Affiliation Edinburgh Clinical Research Facility, University of Edinburgh, Edinburgh, United Kingdom
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Archie Campbell,
Roles Data curation, Writing – review & editing
Affiliation Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom
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Rosie M. Walker,
Roles Data curation, Writing – review & editing
Affiliations Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom, School of Psychology, University of Exeter, Exeter, United Kingdom
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Caroline Hayward,
Roles Data curation, Funding acquisition, Writing – review & editing
Affiliations Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom, Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom
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Kathryn L. Evans,
Roles Data curation, Funding acquisition, Writing – review & editing
Affiliation Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom
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Andrew M. McIntosh,
Roles Data curation, Funding acquisition, Writing – review & editing
Affiliations Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom, Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, United Kingdom
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Riccardo E. Marioni
Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing
* E-mail: riccardo.marioni@ed.ac.uk
Affiliation Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom
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Blood-based epigenome-wide analyses of 19 common disease states: A longitudinal, population-based linked cohort study of 18,413 Scottish individuals
- Robert F. Hillary,
- Daniel L. McCartney,
- Hannah M. Smith,
- Elena Bernabeu,
- Danni A. Gadd,
- Aleksandra D. Chybowska,
- Yipeng Cheng,
- Lee Murphy,
- Nicola Wrobel,
- Archie Campbell
- Published: July 6, 2023
- https://doi.org/10.1371/journal.pmed.1004247