High-dose versus standard-dose vitamin D supplementation in older adults with COVID-19 (COVIT-TRIAL): A multicenter, open-label, randomized controlled superiority trial

• Cédric Annweiler ,

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft

  * E-mail: Cedric.Annweiler@chu-angers.fr

  Affiliation Department of Geriatric Medicine and Memory Clinic, Research Centre on Autonomy and Longevity, University Hospital, Angers, France; UNIV Angers, UPRES EA 4638, University of Angers, Angers, France

  https://orcid.org/0000-0002-7199-8109

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• Mélinda Beaudenon,

  Roles Methodology, Resources, Validation, Writing – review & editing

  Affiliation Department of Geriatric Medicine and Memory Clinic, Research Centre on Autonomy and Longevity, University Hospital, Angers, France; UNIV Angers, UPRES EA 4638, University of Angers, Angers, France

  https://orcid.org/0000-0002-2898-0325

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• Jennifer Gautier,

  Roles Data curation, Formal analysis, Methodology, Resources, Validation, Visualization, Writing – review & editing

  Affiliation Department of Geriatric Medicine and Memory Clinic, Research Centre on Autonomy and Longevity, University Hospital, Angers, France; UNIV Angers, UPRES EA 4638, University of Angers, Angers, France

  https://orcid.org/0000-0003-0200-9378

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• Justine Gonsard,

  Roles Methodology, Resources, Writing – review & editing

  Affiliation Delegation for Clinical Research and Innovation, Angers University Hospital, Angers, France

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• Sophie Boucher,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Department of ENT Head and Neck Surgery, University Hospital, Angers, France; MitoLab Team Mitochondrial Medecine Research Centre, MitoVasc Intitute, UNIV Angers, CNRS UMR6015, INSERM U1083, University of Angers, Angers, France

  https://orcid.org/0000-0002-7559-0901

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• Guillaume Chapelet,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Department of Geriatric Medicine and Memory Clinic, Research Centre, University Hospital, Nantes, France; Inserm UMR1235, Nantes Université, Nantes, France

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• Astrid Darsonval,

  Roles Methodology, Resources, Writing – review & editing

  Affiliation Department of Pharmacy, Angers University Hospital, Angers, France

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• Bertrand Fougère,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Division of Geriatric Medicine, Tours University Hospital, Tours, France; Education, Ethics, Health (EA 7505), Tours University, Tours, France

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• Olivier Guérin,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Université Côte d’Azur, Centre Hospitalier Universitaire de Nice, Service de Médecine Gériatrique et Thérapeutique, Nice, France; Université Côte d’Azur, CNRS UMR 7284/INSERM U108, Institute for Research on Cancer and Aging Nice (IRCAN), Faculté de Médecine, Nice, France

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• Marjorie Houvet,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Department of Geriatric Medicine, General Hospital, Saumur, France

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• Pierre Ménager,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Department of Geriatric Medicine, General Hospital, Le Mans, France

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• Claire Roubaud-Baudron,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Pôle de Gérontologie Clinique, CHU Bordeaux, Bordeaux, France; INSERM 1053, Univ. Bordeaux, Bordeaux, France

  https://orcid.org/0000-0003-0870-0979

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• Achille Tchalla,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Unité de Recherche Clinique et d’Innovation (URCI) de Gérontologie, Pôle HU Gérontologie Clinique, CHU de Limoges, France; Université de Limoges, IFR GEIST, Laboratoire UR Vie-Santé (Aging and Digital health Lab) Faculté de Medicine de Limoges, Limoges, France

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• Jean-Claude Souberbielle,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliation Service des Explorations Fonctionnelles, Hôpital Necker-Enfants Malades, AP-HP, Paris, France

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• Jérémie Riou,

  Roles Data curation, Formal analysis, Resources, Validation, Visualization, Writing – review & editing

  Affiliation Delegation for Clinical Research and Innovation, Angers University Hospital, Angers, France

  https://orcid.org/0000-0002-7056-9257

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• Elsa Parot-Schinkel,

  Roles Methodology, Resources, Writing – review & editing

  Affiliation Delegation for Clinical Research and Innovation, Angers University Hospital, Angers, France

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• Thomas Célarier,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Department of Clinical Gerontology, University Hospital of Saint-Etienne, Saint-Etienne, France; Chaire Santé des Ainés, University of Jean Monnet, Saint-Etienne, France

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•  [ ... ],
• on behalf of the COVIT-TRIAL study group

  ¶Membership of the COVIT-TRIAL study group is provided in S1 Supplemental Appendix.

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