Brain-based measures of nociception during general anesthesia with remifentanil: A randomized controlled trial

• Keerthana Deepti Karunakaran ,

  Contributed equally to this work with: Keerthana Deepti Karunakaran, Barry D. Kussman

  Roles Data curation, Formal analysis, Investigation, Methodology, Software, Writing – original draft, Writing – review & editing

  Affiliation The Center for Pain and the Brain, Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

  https://orcid.org/0000-0001-6448-9341

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• Barry D. Kussman ,

  Contributed equally to this work with: Keerthana Deepti Karunakaran, Barry D. Kussman

  Roles Conceptualization, Data curation, Investigation, Methodology, Resources, Supervision, Writing – review & editing

  Affiliation Division of Cardiac Anesthesia, Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

  https://orcid.org/0000-0002-3024-5792

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• Ke Peng,

  Roles Data curation, Methodology, Writing – review & editing

  Affiliations The Center for Pain and the Brain, Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America, Département en Neuroscience, Centre de Recherche du CHUM, l’Université de Montréal Montreal, Québec, Canada

  https://orcid.org/0000-0003-1732-0492

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• Lino Becerra,

  Roles Conceptualization, Investigation, Resources, Supervision, Writing – review & editing

  Affiliation The Center for Pain and the Brain, Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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• Robert Labadie,

  Roles Data curation, Formal analysis, Writing – review & editing

  Affiliation The Center for Pain and the Brain, Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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• Rachel Bernier,

  Roles Data curation, Project administration, Writing – review & editing

  Affiliation Division of Cardiac Anesthesia, Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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• Delany Berry,

  Roles Data curation, Formal analysis, Resources, Writing – review & editing

  Affiliation The Center for Pain and the Brain, Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

  https://orcid.org/0000-0002-6556-2800

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• Stephen Green,

  Roles Formal analysis, Methodology, Writing – review & editing

  Affiliation The Center for Pain and the Brain, Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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• David Zurakowski,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliation Division of Biostatistics, Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

  https://orcid.org/0000-0003-3610-6942

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• Mark E. Alexander,

  Roles Conceptualization, Data curation, Project administration, Writing – review & editing

  Affiliation Department of Cardiology, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

  https://orcid.org/0000-0002-7540-3504

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• David Borsook

  Roles Conceptualization, Funding acquisition, Investigation, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: dborsook@mgh.harvard.edu

  Affiliations The Center for Pain and the Brain, Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Psychiatry and Radiology, Massachusetts General Hospital, Boston, Massachusetts, United States of America

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