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Open Access
Peer-reviewed
Research Article
Evaluating the relationship between circulating lipoprotein lipids and apolipoproteins with risk of coronary heart disease: A multivariable Mendelian randomisation analysis
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Tom G. Richardson ,
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – review & editing
* E-mail: tom.g.richardson@bristol.ac.uk (TGR); pa-ieudirector@bristol.ac.uk (GDS)
Affiliations Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom, Population Health Sciences, Bristol Medical School, University of Bristol, Barley House, Oakfield Grove, Bristol, United Kingdom
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Eleanor Sanderson,
Roles Conceptualization, Investigation, Methodology, Software, Writing – review & editing
Affiliations Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom, Population Health Sciences, Bristol Medical School, University of Bristol, Barley House, Oakfield Grove, Bristol, United Kingdom
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Tom M. Palmer,
Roles Investigation, Methodology, Writing – review & editing
Affiliations Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom, Population Health Sciences, Bristol Medical School, University of Bristol, Barley House, Oakfield Grove, Bristol, United Kingdom
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Mika Ala-Korpela,
Roles Investigation, Writing – review & editing
Affiliations Systems Epidemiology, Baker Heart and Diabetes Institute, Melbourne, Australia, Computational Medicine, Faculty of Medicine, University of Oulu and Biocenter Oulu, Oulu, Finland, NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, Kuopio, Finland, Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Faculty of Medicine, Nursing and Health Sciences, The Alfred Hospital, Monash University, Melbourne, Australia
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Brian A. Ference,
Roles Investigation, Writing – review & editing
Affiliations Centre for Naturally Randomized Trials, University of Cambridge, Cambridge, United Kingdom, MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom
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George Davey Smith ,
Roles Conceptualization, Data curation, Investigation, Methodology, Supervision, Writing – original draft, Writing – review & editing
* E-mail: tom.g.richardson@bristol.ac.uk (TGR); pa-ieudirector@bristol.ac.uk (GDS)
¶‡ These authors are joint senior authors on this work.
Affiliations Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom, Population Health Sciences, Bristol Medical School, University of Bristol, Barley House, Oakfield Grove, Bristol, United Kingdom
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Michael V. Holmes
Roles Conceptualization, Investigation, Methodology, Supervision, Visualization, Writing – original draft, Writing – review & editing
¶‡ These authors are joint senior authors on this work.
Affiliations Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom, Medical Research Council Population Health Research Unit, University of Oxford, Oxford, United Kingdom, Clinical Trial Service Unit & Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom
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Evaluating the relationship between circulating lipoprotein lipids and apolipoproteins with risk of coronary heart disease: A multivariable Mendelian randomisation analysis
- Tom G. Richardson,
- Eleanor Sanderson,
- Tom M. Palmer,
- Mika Ala-Korpela,
- Brian A. Ference,
- George Davey Smith,
- Michael V. Holmes
![PLOS](/resource/img/logo-plos.png)
- Published: March 23, 2020
- https://doi.org/10.1371/journal.pmed.1003062