Artemether-lumefantrine dosing for malaria treatment in young children and pregnant women: A pharmacokinetic-pharmacodynamic meta-analysis

• Frank Kloprogge,

  Roles Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft

  Affiliations WorldWide Antimalarial Resistance Network, Bangkok, Thailand, Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, United Kingdom, Institute for Global Health, University College London, London, United Kingdom

  http://orcid.org/0000-0001-7213-4559

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• Lesley Workman,

  Roles Data curation, Project administration, Validation, Writing – review & editing

  Affiliations WorldWide Antimalarial Resistance Network, Cape Town, South Africa, Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa

  http://orcid.org/0000-0002-3433-6106

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• Steffen Borrmann,

  Roles Investigation, Writing – review & editing

  Affiliations Kenya Medical Research Institute–Wellcome Trust Research Programme, Kilifi, Kenya, Institute for Tropical Medicine, Eberhard Karls University of Tübingen, Tübingen, Germany

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• Mamadou Tékété,

  Roles Investigation, Writing – review & editing

  Affiliations Institute for Tropical Medicine, Eberhard Karls University of Tübingen, Tübingen, Germany, Malaria Research and Training Center, Department of Epidemiology of Parasitic Diseases, Faculty of Pharmacy, University of Science, Techniques and Technologies of Bamako, Bamako, Mali

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• Gilbert Lefèvre,

  Roles Investigation, Writing – review & editing

  Affiliation Novartis, Basel, Switzerland

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• Kamal Hamed,

  Roles Investigation, Writing – review & editing

  Affiliation Novartis Pharmaceuticals, East Hanover, New Jersey, United States of America

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• Patrice Piola,

  Roles Investigation, Writing – review & editing

  Affiliation Institut Pasteur du Cambodge, Phnom Penh, Cambodia

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• Johan Ursing,

  Roles Investigation, Writing – review & editing

  Affiliations Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden, Department of Infectious Diseases, Danderyds Hospital, Stockholm, Sweden, Bandim Health Project, Bissau, Guinea-Bissau

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• Poul Erik Kofoed,

  Roles Investigation, Writing – review & editing

  Affiliations Bandim Health Project, Bissau, Guinea-Bissau, Department of Paediatrics, Kolding Hospital, Kolding, Denmark

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• Andreas Mårtensson,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Women’s and Children’s Health, International Maternal and Child Health, Uppsala University, Uppsala, Sweden

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• Billy Ngasala,

  Roles Investigation, Writing – review & editing

  Affiliation Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania

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• Anders Björkman,

  Roles Investigation, Writing – review & editing

  Affiliation Karolinska Institutet, Stockholm, Sweden

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• Michael Ashton,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Pharmacology, University of Gothenburg, Gothenburg, Sweden

  http://orcid.org/0000-0001-9122-8294

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• Sofia Friberg Hietala,

  Roles Investigation, Writing – review & editing

  Affiliations Department of Pharmacology, University of Gothenburg, Gothenburg, Sweden, Pharmetheus, Uppsala, Sweden

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• Francesca Aweeka,

  Roles Investigation, Writing – review & editing

  Affiliation UCSF School of Pharmacy, San Francisco, California, United States of America

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• Sunil Parikh,

  Roles Investigation, Writing – review & editing

  Affiliation Yale School of Public Health, New Haven, Connecticut, United States of America

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• Leah Mwai,

  Roles Investigation, Writing – review & editing

  Affiliations Kenya Medical Research Institute–Wellcome Trust Research Programme, Kilifi, Kenya, Institute for Tropical Medicine and Joanna Briggs Institute Affiliate Centre for Evidence Based Health Care Evidence Synthesis and Translation Unit, Afya Research Africa, Nairobi, Kenya, International Development Research Centre, Ottawa, Ontario, Canada

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• Timothy M. E. Davis,

  Roles Investigation, Writing – review & editing

  Affiliation Medical School, Faculty of Health and Medical Sciences, The University of Western Australia, Perth, Western Australia, Australia

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• Harin Karunajeewa,

  Roles Investigation, Writing – review & editing

  Affiliation Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia

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• Sam Salman,

  Roles Investigation, Writing – review & editing

  Affiliation Medical School, Faculty of Health and Medical Sciences, The University of Western Australia, Perth, Western Australia, Australia

  http://orcid.org/0000-0002-8276-6784

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• Francesco Checchi,

  Roles Investigation, Writing – review & editing

  Affiliations Epicentre, Paris, France, Department of Infectious Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, United Kingdom

  http://orcid.org/0000-0001-9030-5382

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• Carole Fogg,

  Roles Investigation, Writing – review & editing

  Affiliations Epicentre, Paris, France, Faculty of Science, University of Portsmouth, Portsmouth, United Kingdom

  http://orcid.org/0000-0002-3000-6185

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• Paul N. Newton,

  Roles Investigation, Writing – review & editing

  Affiliations Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, United Kingdom, Lao–Oxford–Mahosot Hospital–Wellcome Trust Research Unit, Vientiane, Laos

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• Mayfong Mayxay,

  Roles Investigation, Writing – review & editing

  Affiliations Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, United Kingdom, Lao–Oxford–Mahosot Hospital–Wellcome Trust Research Unit, Vientiane, Laos, Faculty of Postgraduate Studies, University of Health Sciences, Vientiane, Laos

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• Philippe Deloron,

  Roles Investigation, Writing – review & editing

  Affiliation UMR216 Institut de Recherche pour le Développement, Faculté de Pharmacie, Université Paris Descartes, Paris, France

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• Jean François Faucher,

  Roles Investigation, Writing – review & editing

  Affiliation Centre Hospitalier Universitaire, UMR Inserm 1094 NET, Limoges, France

  http://orcid.org/0000-0002-1629-1194

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• François Nosten,

  Roles Investigation, Writing – review & editing

  Affiliations Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, United Kingdom, Shoklo Malaria Research Unit, Mae Sot, Thailand

  http://orcid.org/0000-0002-7951-0745

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• Elizabeth A. Ashley,

  Roles Investigation, Writing – review & editing

  Affiliations Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, United Kingdom, Myanmar Oxford Clinical Research Unit, Yangon, Myanmar

  http://orcid.org/0000-0002-7620-4822

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• Rose McGready,

  Roles Investigation, Writing – review & editing

  Affiliations Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, United Kingdom, Shoklo Malaria Research Unit, Mae Sot, Thailand

  http://orcid.org/0000-0003-1621-3257

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• Michele van Vugt,

  Roles Investigation, Writing – review & editing

  Affiliations Shoklo Malaria Research Unit, Mae Sot, Thailand, Amsterdam Medical Centre, Amsterdam, The Netherlands

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• Stephane Proux,

  Roles Investigation, Writing – review & editing

  Affiliations Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, United Kingdom, Shoklo Malaria Research Unit, Mae Sot, Thailand

  http://orcid.org/0000-0003-4201-5473

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• Ric N. Price,

  Roles Investigation, Writing – review & editing

  Affiliations Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, United Kingdom, WorldWide Antimalarial Resistance Network, Darwin, Northern Territory, Australia, Global and Tropical Health Division, Menzies School of Health Research, Darwin, Northern Territory, Australia, Charles Darwin University, Darwin, Northern Territory, Australia

  http://orcid.org/0000-0003-2000-2874

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• Juntra Karbwang,

  Roles Investigation, Writing – review & editing

  Affiliation Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan

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• Farkad Ezzet,

  Roles Investigation, Writing – review & editing

  Affiliation Novartis Pharmaceuticals, East Hanover, New Jersey, United States of America

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• Rajesh Bakshi,

  Roles Investigation, Writing – review & editing

  Affiliation Novartis, Basel, Switzerland

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• Kasia Stepniewska,

  Roles Investigation, Writing – review & editing

  Affiliations Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, United Kingdom, WorldWide Antimalarial Resistance Network, Oxford, United Kingdom

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• Nicholas J. White,

  Roles Conceptualization, Investigation, Project administration, Writing – review & editing

  Affiliations Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, United Kingdom, Mahidol–Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand

  http://orcid.org/0000-0002-1897-1978

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• Philippe J. Guerin,

  Roles Conceptualization, Funding acquisition, Investigation, Project administration, Writing – review & editing

  Affiliations Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, United Kingdom, WorldWide Antimalarial Resistance Network, Oxford, United Kingdom

  http://orcid.org/0000-0002-6008-2963

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• Karen I. Barnes,

  Roles Conceptualization, Investigation, Project administration, Writing – review & editing

  Affiliations WorldWide Antimalarial Resistance Network, Cape Town, South Africa, Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa

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•  [ ... ],
• Joel Tarning

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Validation, Visualization, Writing – review & editing

  * E-mail: joel@tropmedres.ac

  Affiliations WorldWide Antimalarial Resistance Network, Bangkok, Thailand, Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, United Kingdom, Mahidol–Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand

  http://orcid.org/0000-0003-4566-4030

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