Cardiovascular and Renal Outcomes of Renin–Angiotensin System Blockade in Adult Patients with Diabetes Mellitus: A Systematic Review with Network Meta-Analyses

• Ferrán Catalá-López ,

  * E-mail: ferran_catala@hotmail.com

  Affiliations Department of Medicine, University of Valencia/INCLIVA Health Research Institute, Valencia, Spain, Division of Pharmacoepidemiology and Pharmacovigilance, Spanish Agency of Medicines and Medical Devices (AEMPS), Madrid, Spain, Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada, Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain

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• Diego Macías Saint-Gerons,

  Affiliation Division of Pharmacoepidemiology and Pharmacovigilance, Spanish Agency of Medicines and Medical Devices (AEMPS), Madrid, Spain

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• Diana González-Bermejo,

  Affiliation Division of Pharmacoepidemiology and Pharmacovigilance, Spanish Agency of Medicines and Medical Devices (AEMPS), Madrid, Spain

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• Giuseppe M. Rosano,

  Affiliation Centre for Clinical and Basic Research, Department of Medical Sciences, Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele Pisana, Rome, Italy

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• Barry R. Davis,

  Affiliation The University of Texas School of Public Health, Houston, Texas, United States of America

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• Manuel Ridao,

  Affiliations Instituto Aragonés de Ciencias de la Salud, Red de Investigación en Servicios de Salud en Enfermedades Crónicas (REDISSEC), Zaragoza, Spain, Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO–Salud Pública), Valencia, Spain

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• Abel Zaragoza,

  Affiliation Division of Pharmacoepidemiology and Pharmacovigilance, Spanish Agency of Medicines and Medical Devices (AEMPS), Madrid, Spain

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• Dolores Montero-Corominas,

  Affiliation Division of Pharmacoepidemiology and Pharmacovigilance, Spanish Agency of Medicines and Medical Devices (AEMPS), Madrid, Spain

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• Aurelio Tobías,

  Affiliation Spanish Council for Scientific Research (CSIC), Barcelona, Spain

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• César de la Fuente-Honrubia,

  Affiliations Division of Pharmacoepidemiology and Pharmacovigilance, Spanish Agency of Medicines and Medical Devices (AEMPS), Madrid, Spain, Area of Budgetary Stability, Ministry of Finance and Public Administrations, Madrid, Spain

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• Rafael Tabarés-Seisdedos,

  Affiliations Department of Medicine, University of Valencia/INCLIVA Health Research Institute, Valencia, Spain, Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain

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• Brian Hutton

  Affiliations Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada, School of Epidemiology, Public Health and Preventive Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada

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