Circulating Mitochondrial DNA in Patients in the ICU as a Marker of Mortality: Derivation and Validation

• Kiichi Nakahira ,

  Contributed equally to this work with: Kiichi Nakahira, Sun-Young Kyung

  Affiliations Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Medicine, Weill Cornell Medical College, New York, New York, United States of America

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• Sun-Young Kyung ,

  Contributed equally to this work with: Kiichi Nakahira, Sun-Young Kyung

  Affiliations Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Internal Medicine, Gachon University Gil Hospital, Incheon, South Korea

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• Angela J. Rogers,

  Affiliations Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America, Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Stanford University, Stanford, California, United States of America

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• Lee Gazourian,

  Affiliation Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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• Sojung Youn,

  Affiliation Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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• Anthony F. Massaro,

  Affiliation Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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• Carolina Quintana,

  Affiliation Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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• Juan C. Osorio,

  Affiliation Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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• Zhaoxi Wang,

  Affiliation Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, United States of America

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• Yang Zhao,

  Affiliation Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, United States of America

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• Laurie A. Lawler,

  Affiliation Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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• Jason D. Christie,

  Affiliation Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

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• Nuala J. Meyer,

  Affiliation Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

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• Finnian R. Mc. Causland,

  Affiliation Renal Division, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America

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• Sushrut S. Waikar,

  Affiliation Renal Division, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America

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• Aaron B. Waxman,

  Affiliation Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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• Raymond T. Chung,

  Affiliation Division of Gastroenterology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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• Raphael Bueno,

  Affiliation Division of Thoracic Surgery, Department of Surgery, Brigham and Women's Hospital, Boston, Massachusetts, United States of America

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• Ivan O. Rosas,

  Affiliation Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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• Laura E. Fredenburgh,

  Affiliation Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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• Rebecca M. Baron,

  Affiliation Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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• David C. Christiani,

  Affiliations Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, United States of America, Pulmonary and Critical Care Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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• Gary M. Hunninghake ,

  ¶Joint senior author on this work with: Gary M. Hunninghake, Augustine M. K. Choi.

  Affiliation Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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•  [ ... ],
• Augustine M. K. Choi

  * E-mail: amc2056@med.cornell.edu

  ¶Joint senior author on this work with: Gary M. Hunninghake, Augustine M. K. Choi.

  Affiliations Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Medicine, Weill Cornell Medical College, New York, New York, United States of America, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea

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