Biomarker Profiling by Nuclear Magnetic Resonance Spectroscopy for the Prediction of All-Cause Mortality: An Observational Study of 17,345 Persons

• Krista Fischer ,

  Contributed equally to this work with: Krista Fischer, Johannes Kettunen, Peter Würtz

  * E-mail: krista.fischer@ut.ee (KF); peter.wurtz@computationalmedicine.fi (PW)

  Affiliation The Estonian Genome Center, University of Tartu, Tartu, Estonia

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• Johannes Kettunen ,

  Contributed equally to this work with: Krista Fischer, Johannes Kettunen, Peter Würtz

  Affiliations Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland, Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland, Computational Medicine, Institute of Health Sciences, University of Oulu and Oulu University Hospital, Oulu, Finland

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• Peter Würtz ,

  Contributed equally to this work with: Krista Fischer, Johannes Kettunen, Peter Würtz

  * E-mail: krista.fischer@ut.ee (KF); peter.wurtz@computationalmedicine.fi (PW)

  Affiliations Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland, Computational Medicine, Institute of Health Sciences, University of Oulu and Oulu University Hospital, Oulu, Finland

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• Toomas Haller,

  Affiliation The Estonian Genome Center, University of Tartu, Tartu, Estonia

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• Aki S. Havulinna,

  Affiliation Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland

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• Antti J. Kangas,

  Affiliation Computational Medicine, Institute of Health Sciences, University of Oulu and Oulu University Hospital, Oulu, Finland

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• Pasi Soininen,

  Affiliations Computational Medicine, Institute of Health Sciences, University of Oulu and Oulu University Hospital, Oulu, Finland, NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, Kuopio, Finland

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• Tõnu Esko,

  Affiliations The Estonian Genome Center, University of Tartu, Tartu, Estonia, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America, Division of Genetics, Children's Hospital, Boston, Massachusetts, United States of America, Division of Endocrinology, Children's Hospital, Boston, Massachusetts, United States of America, Program in Genomics, Children's Hospital, Boston, Massachusetts, United States of America, Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America

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• Mari-Liis Tammesoo,

  Affiliation The Estonian Genome Center, University of Tartu, Tartu, Estonia

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• Reedik Mägi,

  Affiliation The Estonian Genome Center, University of Tartu, Tartu, Estonia

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• Steven Smit,

  Affiliation The Estonian Genome Center, University of Tartu, Tartu, Estonia

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• Aarno Palotie,

  Affiliations Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America, Wellcome Trust Sanger Institute, Hinxton, United Kingdom

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• Samuli Ripatti,

  Affiliations Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland, Wellcome Trust Sanger Institute, Hinxton, United Kingdom

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• Veikko Salomaa,

  Affiliation Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland

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• Mika Ala-Korpela ,

  ¶These authors are joint senior authors on this work.

  Affiliations Computational Medicine, Institute of Health Sciences, University of Oulu and Oulu University Hospital, Oulu, Finland, NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, Kuopio, Finland, Computational Medicine, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom

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• Markus Perola ,

  ¶These authors are joint senior authors on this work.

  Affiliations The Estonian Genome Center, University of Tartu, Tartu, Estonia, Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland

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•  [ ... ],
• Andres Metspalu

  ¶These authors are joint senior authors on this work.

  Affiliations The Estonian Genome Center, University of Tartu, Tartu, Estonia, Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia

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