Lung Cancer Occurrence in Never-Smokers: An Analysis of 13 Cohorts and 22 Cancer Registry Studies

Michael J Thun; Lindsay M Hannan; Lucile L Adams-Campbell; Paolo Boffetta; Julie E Buring; Diane Feskanich; W. Dana Flanders; Sun Ha Jee; Kota Katanoda; Laurence N Kolonel; I-Min Lee; Tomomi Marugame; Julie R Palmer; Elio Riboli; Tomotaka Sobue; Erika Avila-Tang; Lynne R Wilkens; Jon M Samet

doi:10.1371/journal.pmed.0050185

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Peer-reviewed

Research Article

Lung Cancer Occurrence in Never-Smokers: An Analysis of 13 Cohorts and 22 Cancer Registry Studies

Michael J Thun ,

*To whom correspondence should be addressed. E-mail: mthun@cancer.org

Affiliation American Cancer Society, Atlanta, Georgia, United States of America
⨯
Lindsay M Hannan,

Affiliation American Cancer Society, Atlanta, Georgia, United States of America
⨯
Lucile L Adams-Campbell,

Affiliation Howard University Cancer Center, Washington, D. C., United States of America
⨯
Paolo Boffetta,

Affiliation International Agency for Research on Cancer (IARC), Lyon, France
⨯
Julie E Buring,

Affiliation Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Diane Feskanich,

Affiliation Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America
⨯
W. Dana Flanders,

Affiliations American Cancer Society, Atlanta, Georgia, United States of America , Rollins School of Public Health, Emory University, Atlanta, Georgia, United States of America
⨯
Sun Ha Jee,

Affiliation Institute for Health Promotion, Graduate School of Public Health, Yonsei University, Seoul, Korea
⨯
Kota Katanoda,

Affiliation Cancer Information Services and Surveillance Division, Center for Cancer Control and Information Services, National Cancer Center, Tokyo, Japan
⨯
Laurence N Kolonel,

Affiliation Cancer Research Center of Hawaii, University of Hawaii, Honolulu, Hawaii, United States of America
⨯
I-Min Lee,

Affiliation Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Tomomi Marugame,

Affiliation Cancer Information Services and Surveillance Division, Center for Cancer Control and Information Services, National Cancer Center, Tokyo, Japan
⨯
Julie R Palmer,

Affiliation Slone Epidemiology Center, Boston University, Boston, Massachusetts, United States of America
⨯
Elio Riboli,

Affiliation International Agency for Research on Cancer (IARC), Lyon, France
⨯
Tomotaka Sobue,

Affiliation Cancer Information Services and Surveillance Division, Center for Cancer Control and Information Services, National Cancer Center, Tokyo, Japan
⨯
Erika Avila-Tang,

Affiliation Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America
⨯
Lynne R Wilkens,

Affiliation Cancer Research Center of Hawaii, University of Hawaii, Honolulu, Hawaii, United States of America
⨯
[ ... ],
Jon M Samet

Affiliation Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America
⨯
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Lung Cancer Occurrence in Never-Smokers: An Analysis of 13 Cohorts and 22 Cancer Registry Studies

Michael J Thun,
Lindsay M Hannan,
Lucile L Adams-Campbell,
Paolo Boffetta,
Julie E Buring,
Diane Feskanich,
W. Dana Flanders,
Sun Ha Jee,
Kota Katanoda,
Laurence N Kolonel

Published: September 9, 2008
https://doi.org/10.1371/journal.pmed.0050185

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RE: hpv infection

Posted by plosmedicine on 31 Mar 2009 at 00:30 GMT

Author: Michael Thun
Position: Vice President of Epidemiology & Surveillance Research
Institution: American Cancer Society
E-mail: mthun@cancer.org
Submitted Date: September 17, 2008
Published Date: September 19, 2008
This comment was originally posted as a “Reader Response” on the publication date indicated above. All Reader Responses are now available as comments.

Although the hypothesis that HPV may affect lung cancer risk is intriguing, as of now there is very limited evidence to support it.

No competing interests declared.

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Lung Cancer Occurrence in Never-Smokers: An Analysis of 13 Cohorts and 22 Cancer Registry Studies

Lung Cancer Occurrence in Never-Smokers: An Analysis of 13 Cohorts and 22 Cancer Registry Studies

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RE: hpv infection

Posted by plosmedicine on 31 Mar 2009 at 00:30 GMT