About the Authors

Joshua A. Bell

Roles Conceptualization, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

j.bell@bristol.ac.uk

Affiliation Medical Research Council Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom

David Carslake

Roles Conceptualization, Investigation, Methodology, Supervision, Writing – review & editing

Affiliation Medical Research Council Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom

Kaitlin H. Wade

Roles Investigation, Methodology, Writing – review & editing

Affiliation Medical Research Council Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom

Rebecca C. Richmond

Roles Investigation, Methodology, Writing – review & editing

Affiliation Medical Research Council Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom

Ryan J. Langdon

Roles Investigation, Writing – review & editing

Affiliation Medical Research Council Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom

Emma E. Vincent

Roles Investigation, Writing – review & editing

Affiliations Medical Research Council Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom, School of Cellular and Molecular Medicine, University of Bristol, Bristol, United Kingdom

Michael V. Holmes

Roles Investigation, Methodology, Writing – review & editing

Affiliations Medical Research Council Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom, Clinical Trial Service Unit & Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom, Medical Research Council Population Health Research Unit, University of Oxford, Oxford, United Kingdom, National Institute for Health Research Oxford Biomedical Research Centre, Oxford University Hospital, Oxford, United Kingdom

Nicholas J. Timpson

Roles Investigation, Methodology, Writing – review & editing

Affiliation Medical Research Council Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom

George Davey Smith

Roles Conceptualization, Investigation, Methodology, Supervision, Writing – review & editing

Affiliation Medical Research Council Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom

Competing Interests

I have read the journal's policy and the authors of this manuscript have the following competing interests: GDS is a member of the Editorial Board of PLOS Medicine. MVH has collaborated with Boehringer Ingelheim in research, and in accordance with the policy of The Clinical Trial Service Unit and Epidemiological Studies Unit (University of Oxford), did not accept any personal payment. There are no further interests to declare.