About the Authors

Lesley E. Scott

lesley.scott@nhls.ac.za

Affiliation Department of Molecular Medicine and Hematology, University of the Witwatersrand, Johannesburg, South Africa

Kerrigan McCarthy

Affiliation Wits Reproductive Health and HIV Institute, University of the Witwatersrand, Johannesburg, South Africa

Natasha Gous

Affiliation Department of Molecular Medicine and Hematology, University of the Witwatersrand, Johannesburg, South Africa

Matilda Nduna

Affiliation National Health Laboratory Service, Johannesburg, South Africa

Annelies Van Rie

Affiliation Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

Ian Sanne

Affiliation Clinical HIV Research Unit, Department of Medicine, University of the Witwatersrand, and Right to Care, Johannesburg, South Africa

Willem F. Venter

Affiliation Wits Reproductive Health and HIV Institute, University of the Witwatersrand, Johannesburg, South Africa

Adrian Duse

Affiliations National Health Laboratory Service, Johannesburg, South Africa, Department of Clinical Microbiology and Infectious Diseases, University of the Witwatersrand, Johannesburg, South Africa

Wendy Stevens

Affiliations Department of Molecular Medicine and Hematology, University of the Witwatersrand, Johannesburg, South Africa, National Health Laboratory Service, Johannesburg, South Africa

Competing Interests

The Academic Editor, Madhukar Pai, declares that he consults for the Bill & Melinda Gates Foundation (BMGF). The BMGF supported the Foundation for Innovative New Diagnostics (FIND), which was involved in the development of the Xpert MTB/RIF assay. He also co-chairs the Stop TB Partnership's New Diagnostics Working Group that was involved in the WHO endorsement of the Xpert assay. The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: LS KM WS IS FV AD. Performed the experiments: NG LS. Analyzed the data: LS KM AVR NG. Contributed reagents/materials/analysis tools: WS IS FV. Wrote the paper: LS KM AVR NG WS. ICMJE criteria for authorship read and met: LS KM NG MN AVR IS FV AD WS. Agree with the manuscript's results and conclusions: LS KM NG MN AVR IS FV AD WS. Enrolled patients: MN. Wrote the first draft of the paper: LS KM NG WS. Clinic management where study conducted: FV IS. Managed infection control necessary for study to be performed and assistance with RIF resistance data interpretation: AD.